NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
NPACT
Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound:
(R)-tylophorine
Targets
Gene Name
Gene ID
Cancer
Cell Lines
IC
50
ED
50
EC
50
GI
50
Remark
References
CYC3B
cyclin-A2-2
831001
Hepatoma
Hep G2
-
-
-
237±32 nM
In asynchronized HepG2 , cyclin A2 level was significantly lower with tylophorine treatment than with DMSO and dehydro-tylophorine treatment.
19501048
CYC3B
cyclin-A2-2
831001
Nasopharyngeal carcinoma cells
HONE-1
-
-
-
114±6 nM
In asynchronized HONE-1 , cyclin A2 level was significantly lower with tylophorine treatment than with DMSO and dehydro-tylophorine treatment.
19501048
CYC3B
cyclin-A2-2
831001
Carcinoma
NUGC-3
-
-
-
134±9 nM
In asynchronized NUGC-3 , cyclin A2 level was significantly lower with tylophorine treatment than with DMSO and dehydro-tylophorine treatment.
19501048
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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.