Help Page of NFKBIn

This webserver enables researchers working in the field of drug discovery using inhibitor designing against TNF alpha induced NF-KB inhibitor. This server scans chemical compounds as potential TNF alpha induced NF-KB inhibitors and non-inhibitors. Users can upload chemical compounds in SDF/SMILES/mol format files.

Predict: This module enables users to scan the chemical molecules as Tumor Necrosis Factor-a-specific NF-kB inhibitor or non-inhibitor. Here the users are allowed to paste or upload a file with multiple molecules in several file formats like; SMILES, SDF, and MOL.



Draw:This module allows users to draw the chemical structure of the compound using the Ketcher. Users have the choice to either build a new molecule or edit/modify an existing molecule. This module further predicts the drawn chemical compound as TNF-a induced NF-KB inhibitor.



Analog Design: This module facilites users to design analogs of their lead molecule. A user needs to submit a scaffold structure along with the building blocks and linker molecules. Using the submitted information, the web server uses the SmiLib package to design analogs. It also classifies the analogs generated as TNF-a induced NF-KB inhibitor.