Browse result page of ImmunoSPdb

The total number entries retrieved from this search are 437
IDNameSequenceLengthChiralityN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicNatureSourceTargetMechanism of ActionIn vivo/ In vitroCell LineIC-50In vivo ModelAssay TypeLethal DoseCombination TherapyPubmed IDYear of Publication
1322NoneGLDLLTAEQGGICLALQEKCCF22LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T13NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1324HTLV-I VirusQNRRGLDLLFWEQGGLCLALQEQCRF26LNoneNoneNoneLinearProtein DerivedHuman T-cell Leukemia Virus envelope proteinsHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T15NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1326Feline VirusQNRRGLDILFLQEGGLCAALKEECCF26LNoneNoneNoneLinearProtein DerivedFeline virus envelope proteinsHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T17NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1329NoneQNRRGLDLLFLKEGGL16LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T20NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1330Formula (IVb) CS-1QNRRGLDLLFWEQGGL16LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T21NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1331Formula (IVc) CS-2QNRLALDYLLAAEGGV16LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T22NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1332Formula (IVd) CS-3QARILAVERYLLDQQL16LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T23NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1333Formula (Ive)-CS-SRV 17QNRRGLDLLTAEQGGI16LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T24NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1334NoneQNRLDYLLAAEGGVCGKFNLTNYC24LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T25NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1337NoneAQNRRGLDLLFLKEGGL17LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T28NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1338NoneLQARILAVERYLKDQQL17LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T29NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1347Formula 9[RKD-NH-CH2]26LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1348Formula 10RKD-NH-CH2-CH2-NH-DKR6LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1349Formula 11[RKDV-NH-CH2]28LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1350Formula 12[RLDV-NH-CH2]28LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1351Formula 13KSKL4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1352Formula 14SKL3LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1353Formula 15SSST4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1354Formula 16LET3LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1355Formula 17LTET4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1356Formula 18PKLT4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1357Formula 19KKTE4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1358Formula 20KHL3LNoneAmidationNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1364CB11PPTGPLGPKGQTGELGIAGFKGEQGPK26LNoneNoneNoneLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 57209551998
1367CB11PPTGPLGPKGQTGELGIAGFKGEQGPK26LNoneNoneNoneLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 57831881998
1370CB11PPTGPLGPKGQTGELGIAGFKGEQGPK26LNoneNoneNoneLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 58434451998
1371A2.94-112TLQRMYGCDVGSDWRFLRG19LNoneNoneNoneLinearProtein Derivedα2 domain of HLA-A2B-Lymphoblastoid cells (B-cell)Inhibit by binding to variable T cell receptorIn vitroAJY CTL cell lineNANoneHummoral Immune Response assayNANAUS 58885121999
1372A2.98-113MYGCDVGSDWRFLRGY16LNoneNoneNoneLinearProtein Derivedα2 domain of HLA-A2B-Lymphoblastoid cells (B-cell)Inhibit by binding to variable T cell receptorIn vitroAJY CTL cell lineNANoneHummoral Immune Response assayNANAUS 58885121999
1373A2.101-108CDVGSDWR8LNoneNoneNoneLinearProtein Derivedα2 domain of HLA-A2B-Lymphoblastoid cells (B-cell)Inhibit by binding to variable T cell receptorIn vitroJY cells (HKA-A2, B7, DR4,6)NANoneHummoral Immune Response assayNANAUS 58885121999
1374Nef2-19GGKWSKSSVIGWPAVRERMRR21LNoneNoneNoneLinearNaturalNL4.3 strain of HIV-1T -cellsDownregulates CD4 and IL-2In vitroMT-2 cellsNANoneElectroporation techniqueNAGSTUS 59626351999
1376SEQ ID3CIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC33LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1378SEQ ID5RSCIDTIPKSRCTAFECKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1379SEQ ID6RSCIDTIPKSRCTAFQCKKSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1380SEQ ID7RSCIDTIPKSRCTAFQCKHSMEYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1383SEQ ID10RSCATIPKSRCTAAQCKHSMKYRLSFCRKRCGTC34LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1384SEQ ID11RSCIDSTIPKSRCTAAQKHSMKYRASFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1385SEQ ID12RSCADTIPKSRCTAAQCKHSMKYRASFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1386SEQ ID13SSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1387SEQ ID14RSCIDTIPQSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1388SEQ ID15RSCIDTIPKSQCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1389SEQ ID16RSCIDTIPKSRCTAAQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1390SEQ ID17RSCIDTIPKSQCTAWQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1391SEQ ID18RSCIDTIPKSQCTAFQCAHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1393SEQ ID20RSCIDTIPKSRCTAFQCKHSMAYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1397SEQ ID24RSCIDTIPKSRCTAFQCRHSMRYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1398SEQ ID25RSCIDTIPKSRCTAFQCKHSMKFRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1401SEQ ID28RSCIDTIPKSRCTAFQCKHSMKYALSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1402SEQ ID29ASCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1403SEQ ID30RACIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1404SEQ ID31RSCADTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000