1086 | Ac1-9 | ASQKRPSQR | 9 | L | Acetylation | None | None | Linear | Protein Derived | From myelin basic protein | IL-10 and IL-2 | peptide-induced regulatory cells suppress the response of naive T cells and leads to the generation of IL-10-secreting regulatory cells | Both | purified T cells | NA | Tg4 transgenic mouse | CD4 T cell Proliferation assays, Cytokine protein levels assays | NA | NA | 12538682 | 2003 |
1087 | MHC-binding analog (Ac1-9[4Y]) | ASQYRPSQR | 9 | L | Acetylation | None | None | Linear | Synthetic | Analog of Ac1-9 | IL-10 and IL-3 | peptide-induced regulatory cells suppress the response of naive T cells and leads to the generation of IL-10-secreting regulatory cells | Both | purified T cells | NA | Tg4 transgenic mouse | CD4 T cell Proliferation assays, Cytokine protein levels assays | NA | NA | 12538682 | 2003 |
1438 | SEQ ID10 | rlllrlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1439 | SEQ ID11 | rvllrlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1440 | SEQ ID12 | rillrlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1441 | SEQ ID13 | rlvlrlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1442 | SEQ ID14 | rlilrlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1443 | SEQ ID15 | rllvrlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1444 | SEQ ID16 | rllirlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1445 | SEQ ID17 | rlllrvllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1446 | SEQ ID18 | rlllrillgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1447 | SEQ ID19 | rlllrlvlgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1448 | SEQ ID20 | rlllrlilgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1449 | SEQ ID21 | rlllrllvgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1450 | SEQ ID22 | rlllrlligy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1451 | SEQ ID23 | rwllrlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1452 | SEQ ID24 | rlwlrlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1453 | SEQ ID25 | rllwrlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1454 | SEQ ID26 | rlllrwllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1455 | SEQ ID27 | rlllrlwlgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1456 | SEQ ID28 | rlllrllwgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1457 | SEQ ID29 | ryllrlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1458 | SEQ ID30 | rlylrlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1459 | SEQ ID31 | rllyrlllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1460 | SEQ ID32 | rlllryllgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1461 | SEQ ID33 | rlllrlylgy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1462 | SEQ ID34 | rlllrllygy | 10 | D | Acetylation | Amidation | None | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1463 | SEQ ID35 | R-nL-nL-nL-R-nL-nL-nLGY | 10 | L | Acetylation | Amidation | nL = norleucine | Linear | Protein Derived | (HLA-B) α1-domain | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | Both | RAW264.7 macrophages cells | NA | CBA mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 6696545 B1 | 2004 |
1495 | SEQ ID15 | rlllrlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC70 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1496 | SEQ ID16 | rvllrlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC71 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1497 | SEQ ID17 | rillrlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC72 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1498 | SEQ ID18 | rlvlrlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC73 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1499 | SEQ ID19 | rlilrlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC74 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1500 | SEQ ID20 | rllvrlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC75 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1501 | SEQ ID21 | rllirlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC76 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1502 | SEQ ID22 | rlllrvllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC77 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1503 | SEQ ID23 | rlllrillGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC78 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1504 | SEQ ID24 | rlllrlvlGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC79 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1505 | SEQ ID25 | rlllrlilGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC80 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1506 | SEQ ID26 | rlllrllvGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC81 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1507 | SEQ ID27 | rlllrlliGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC82 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1508 | SEQ ID28 | rwllrlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC83 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1509 | SEQ ID29 | rlwlrlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC84 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1510 | SEQ ID30 | rllwrlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC85 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1511 | SEQ ID31 | rlllrwllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC86 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1512 | SEQ ID32 | rlllrlwlGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC87 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1513 | SEQ ID33 | rlllrllwGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC88 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1514 | SEQ ID34 | ryllrlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC89 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1515 | SEQ ID35 | rlylrlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC90 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |
1516 | SEQ ID36 | rllyrlllGy | 10 | Mix | Acetylation | Amidation | None | Linear | Synthetic | NA | NA | Inhibited T-cell proliferation, various inflammatory cytokines production. | In vivo | None | 2.5-10micromolar against binding to peptides to HSC91 | C57BL6/J, Balb/c and CBA/J mice | Enzyme-linked immunosorbent assay (ELISA) | NA | LPS | US 7267822 B2 | 2007 |