| Primary information |
|---|
| ID | 1087 |
| Peptide Name | MHC-binding analog (Ac1-9[4Y]) |
| Sequence | ASQYRPSQR |
| Length | 9 |
| Chirality | L |
| N-terminal Modification | Acetylation |
| C-terminal Modification | None |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Nature | Synthetic |
| Source of Origin | Analog of Ac1-9 |
| Target | IL-10 and IL-3 |
| Mechanism of Action | peptide-induced regulatory cells suppress the response of naive T cells and leads to the generation of IL-10-secreting regulatory cells |
| In vitro/In vivo | Both |
| Cell Line | purified T cells |
| Inhibition Concentartion | NA |
| In vivo Model | Tg4 transgenic mouse |
| Assay | CD4 T cell Proliferation assays, Cytokine protein levels assays |
| Lethal Dose | NA |
| Combination Therapy | NA |
| Pubmed ID | 12538682 |
| Year of Publication | 2003 |
| 3-D Structure |  View in Jmol or Download Structure |
