This webserver has been designed to help the scientific community in vaccine design and development. This server predict IL-6 inducing peptides.
This page provides help on different modules of server. Following are major modules in this server:
Predict: This module allows users to predict the IL-6 inducing peptide/epitope in a set of peptides or peptide library (virtual screening). User may submit large number of peptides and server will predict and rank them based on their potential to induce IL-6.
Design: It generate mutant of a query peptide and predict IL-6 inducing epitopes in mutants. This server allows users to identify minimum mutations required to increase its potency.
Protein Scan: This module allows user to identify regions in a protein, which are contributing in IL-6 induction, which may be further removed or altered. The other way round, here users can also search a protein sequence to find out novel IL-6 inducing peptides.
Motif Scan: This module allows users to scan or map IL-6 motifs in the query sequence, using MEME/MAST and MERCI programs.
BLAST Scan: This page allows users to search the query protein sequence against the database of known IL-6 inducers using similarity-based search method, i.e. BLAST.