Welcome to the Help Page of HLA-DR4Pred2.0
HLA-DR4Pred2.0 Webserver
This webserver has been designed to help the scientific community in order to predict, scan, or design the HLA-Class II allele HLA-DRB1*04:01 binders using sequence information. There are five mojor modules available in the server such as: |
This page provides help on different modules of server. Following are major modules in this server:
PREDICT:
This module allows users to predict the HLA-DRB1*04:01 binding peptide in a set of peptides or peptide library (virtual screening). User may submit large number of peptides and server will predict and rank them based on their potential to bind HLA-DRB1*04:01.
SCAN:
This module allows user to identify regions in a protein, which can act as HLA-DRB1*04:01 binders, which may be further removed or altered. The other way round, here users can also search a protein sequence to find out novel HLA-DRB1*04:01 binding peptides.
It generate all the plausible mutants of the query peptide(s) and predict HLA-DRB1*04:01 binders in mutants. This server allows users to identify minimum mutations required to increase its potency.
This page allows users to search the query peptide sequence(s) against the database of known HLA-DRB1*04:01 binders using similarity-based search method, i.e. BLAST.
This page allow users to search for motifs derived using known HLA-DRB1*04:01 binders, in the query peptide sequence(s) using MERCI software.
