Designing T1DM associated peptides

This module is developed for generating all possible mutant of a peptide by mutating single residue at a time. This module also predict whether mutants is T1DM causing. In summary this module allows to identify best mutant that have highest potency for inducing type1 diabetes. Server allow user to sort mutants based on their score ( probability of T1DM causing peptides) so user can select best mutant. In addition it allows user to further generate all possible mutants of a mutants. In summary, this module allow user to design best T1DM inducing peptide by identifying most important mutation in users peptide. For more help please visit Help.

Type or paste peptide sequence(s) in FASTA format:
    


OR   Submit sequence file:

Select Prediction Method:       DPC based   Hybrid (DPC + BLAST)  

Choose Probability Threshold For Hybrid method:  

Physicochemical Properties to Be Displayed :
 Amphipathicity    Charge    Hydropathicity    Hydrophilicity    Hydrophobicity  
 Molecular weight    Net Hydrogen    pI    Side bulk    Steric hinderance