Welcome to Sequence Card of Peptide
Details of CPPsite entry with Sequence RGGRLSYSRRRFSTSTGR |
| Primary information | |
|---|---|
| PEPTIDE SEQUENCE | RGGRLSYSRRRFSTSTGR |
| CPPsite ID | 2576, 2577, 2578, 1480, |
| PEPTIDE NAME | Synb1-ELP-PKI, Synb1-ELP, Synb1-ELP-TRTK, SynB1 |
| CHIRALITY | L, L, L, L |
| LINEAR/CYCLIC | Linear, Linear, Linear, Linear |
| SOURCE | Synthetic, Synthetic, Synthetic, Protein derived |
| CATEGORY | NA, NA, NA, Antimicrobial |
| SUB CELLULAR LOCALIZATION | NA, Nucleus, Nucleus, Endocytic vesicles |
| N-TERMINAL MODIFICATION | Free, Free, Free, Conjugation with NBD and TAMRA |
| C-TERMINAL MODIFICATION | Free, Free, Free, Free |
| CHEMICAL MODIFICATION | NA, NA, NA, NA |
| UPTAKE EFFICIENCY | NA, NA, NA, Lower than pAntp-(43-58) and SynB5 |
| PROPOSED UPTAKE MECHANISM | NA, NA, NA, Adsorptive-mediated endocytic process |
| INVITRO/INVIVO | In vitro and in vivo, In vitro and in vivo, In vitro and in vivo, In vitro |
| CELL LINE | Green fluorescent protein (GFP)-ATXN1[82Q] expressing HEK cells, Green fluorescent protein (GFP)-ATXN1[82Q] expressing HEK cells, Green fluorescent protein (GFP)-ATXN1[82Q] expressing HEK cells, K562 cells |
| In VIVO MODEL | 3-week-old WT mice, 3-week-old WT mice, 3-week-old WT mice, NA |
| CARGO | Peptide (PKA inhibitory peptide), Fluorophore (Rhodamine), Peptide (S100B inhibitory peptide), Fluorophore (NBD and TAMRA) |
| PMID | 24903464, 24903464, 24903464, 12783857 |
| PATENT | Unknown, Unknown, Unknown, Unknown |
| Tertiary Structure (Technique) | 2576 (PEPstrMOD), 2577 (PEPstrMOD), 2578 (PEPstrMOD), 1480 (PEPstrMOD), |