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This page gives details of CPPsite entry with ID 1480
Primary information
CPPsite ID1480
PEPTIDE SEQUENCERGGRLSYSRRRFSTSTGR
PEPTIDE NAMESynB1
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYAntimicrobial
SUB CELLULAR LOCALIZATIONEndocytic vesicles
N-TERMINAL MODIFICATIONConjugation with NBD and TAMRA
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYLower than pAntp-(43–58) and SynB5
PROPOSED UPTAKE MECHANISMAdsorptive-mediated endocytic process
INVITRO/INVIVOIn vitro
CELL LINEK562 cells
CARGOFluorophore (NBD and TAMRA)
PMID12783857
PATENTUnknown
LENGTH18
Secondary StructureCCSSSCSCCCCTTSSSCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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