This page gives details of CPPsite entry with ID 2576 |
Primary information | |
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CPPsite ID | 2576 |
PEPTIDE SEQUENCE | RGGRLSYSRRRFSTSTGR |
PEPTIDE NAME | Synb1-ELP-PKI |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
N-TERMINAL MODIFICATION | Free |
C-TERMINAL MODIFICATION | Free |
INVITRO/INVIVO | In vitro and in vivo |
CELL LINE | Green fluorescent protein (GFP)-ATXN1[82Q] expressing HEK cells |
In VIVO MODEL | 3-week-old WT mice |
CARGO | Peptide (PKA inhibitory peptide) |
PMID | 24903464 |
PATENT | Unknown |
LENGTH | 18 |
Secondary Structure | CCSSCCCCSSCCSSCTTC |
SMILES | N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |