Designing of Celiac disease-inducing peptides

"Design Module" is developed for producing all possible alternate/mutants of a protein. The new peptide is formed by mutating a single residue at a time. It can also provide a prediction score, to identify the peptide can induce disease causing regions. Users can also sort the prediction score to find the highest scored/best mutant peptide, which can induce disease production. Further, the user can also generate several mutant peptides of the given sequence. It allows the user to design the best mutant with the highest score. Please visit Help page, for more information.

Type or paste peptide sequence(s) in FASTA format:


OR   Submit sequence file:

Select prediction method: Main (Disease Vs Random)   Alternate (Disease Vs Non-Disease)  
Choose Probability Threshold For Main Model:  

Physicochemical Properties to Be Displayed :

 Hydrophobicity    Steric hinderance    Side bulk    Hydropathicity    Amphipathicity   

 Hydrophilicity     Net Hydrogen     Charge     pI     Molecular weight