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| ID | PMID | YEAR | Sequence | Name | Length | Linear/Cyclic | Chirality | Chem-MOD | C-ter MOD | N-ter MOD | Nature | Origin | Cell Line | Cancer Type | Assay | Activity | Testing Time | Tissue Affected | Patents |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| None | 2015 | LPSBD-2 | 20 | Linear | L | None | Free | Free | Anticancer | Synthetic | Hep3B | Liver Cancer | Cell Proliferation assay | ~40% cell survival at 60 µg/ml | 24-h | Liver | None | ||
| None | 2015 | LPSBD-2 | 20 | Linear | L | None | Free | Free | Anticancer | Synthetic | A-549 | Lung Cancer | Cell Proliferation assay | ~20% cell survival at 60 µg/ml | 24-h | Lung | None | ||
| None | 2015 | LPSBD-0 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | Hep3B | Liver Cancer | Cell Proliferation assay | ~40% cell survival at 60 µg/ml | 24-h | Liver | None | ||
| 25854366 | 2015 | BmKn-24 | 9 | Linear | L | None | Free | Free | Antimicrobial | Derivative of Bmkn-2 | HSC-4 | Tongue Squamous Cell Carcinoma | MTT assay | IC50 between 29-97 µg/ml | 24-h | Tongue | None | ||
| None | 2015 | LPSBD-0 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | A-549 | Lung Cancer | Cell Proliferation assay | ~20% cell survival at 60 µg/ml | 24-h | Lung | None | ||
| 25854366 | 2015 | Bmkn-21 | 12 | Linear | L | None | Free | Free | Antimicrobial | Derivative of Bmkn-2 | HSC-4 | Tongue Squamous Cell Carcinoma | MTT assay | IC50 between 29-97 µg/ml | 24-h | Tongue | None | ||
| 25854366 | 2015 | BmKn-23 | 10 | Linear | L | None | Free | Free | Antimicrobial | Derivative of Bmkn-2 | HSC-4 | Tongue Squamous Cell Carcinoma | MTT assay | IC50 between 29-97 µg/ml | 24-h | Tongue | None | ||
| 25854366 | 2015 | BmKn2 | 13 | Linear | L | None | Free | Free | Antimicrobial | Mesobuthus martensii Karsch | HSC-4 | Tongue Squamous Cell Carcinoma | MTT assay | IC50 = 29 µg/mL | 24-h | Tongue | None | ||
| 25854366 | 2015 | Bmkn-22 | 11 | Linear | L | None | Free | Free | Antimicrobial | Derivative of Bmkn-2 | HSC-4 | Tongue Squamous Cell Carcinoma | MTT assay | IC50 between 29-97 µg/ml | 24-h | Tongue | None | ||
| 25802281 | 2015 | TPP3 | 49 | Linear | L | None | Free | Free | Antifungal | pistils from tomato flowers | U-937 | Leukemia Cancer | LDH leakage assay | 35% cytotoxicity at 10 μM | Not Available | Blood | None | ||
| 26527862 | 2015 | TAT-DV1-BH3 | 49 | Linear | Mix | None | Free | Free | Anticancer | Synthetic polypeptide | MDA-MB-231 | Breast cancer | CCK-8 assay | Survival rate = 28.67±8.22% at 80 µM | 72-h | Breast | None | ||
| 26527862 | 2015 | TAT-DV1-BH3 | 49 | Linear | Mix | None | Free | Free | Anticancer | Synthetic polypeptide | MCF-7 | Breast cancer | CCK-8 assay | Survival rate = 36.97±4.22% at 80 µM | 72-h | Breast | None | ||
| 25802281 | 2015 | TPP3 | 49 | Linear | L | None | Free | Free | Antifungal | pistils from tomato flowers | U-937 | Leukemia Cancer | PI uptake assay | 69.6% cell death at 10 μM | Not Available | Blood | None | ||
| 25462264 | 2015 | B1-Glu | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562 | Leukemia cancer | MTT assay | IC50 = 36.6 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-Glu | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7 | Breast Cancer | MTT assay | IC50 = 38.9 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Asp | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7 | Breast Cancer | MTT assay | IC50 = 19.9 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Asp | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562 | Leukemia cancer | MTT assay | IC50 = 44.7 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-His | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562 | Leukemia cancer | MTT assay | IC50 = 10.5 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-His | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7 | Breast Cancer | MTT assay | IC50 = 5.0µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Arg | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7 | Breast Cancer | MTT assay | IC50 = 5.5 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Arg | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562 | Leukemia cancer | MTT assay | IC50 = 8.7 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-Lys | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562/ADM | Leukemia cancer | MTT assay | IC50 = 5.5 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-Lys | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562 | Leukemia cancer | MTT assay | IC50 = 5.5 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-Lys | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7/ADM | Breast Cancer | MTT assay | IC50 = 8.6 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Lys | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7 | Breast Cancer | MTT assay | IC50 = 8.3 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Thr | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562 | Leukemia cancer | MTT assay | IC50 = 17.0 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-Gln | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562 | Leukemia cancer | MTT assay | IC50 = 16.2 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-Thr | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7 | Breast Cancer | MTT assay | IC50 = 19.1 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Gln | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7 | Breast Cancer | MTT assay | IC50 = 14.5 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Gly | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562 | Leukemia cancer | MTT assay | IC50 = 14.8 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-Phe | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562 | Leukemia cancer | MTT assay | IC50 = 3.7 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-Gly | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7 | Breast Cancer | MTT assay | IC50 = 15.8 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Phe | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7 | Breast Cancer | MTT assay | IC50 = 1.3 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Leu | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562/ADM | Leukemia cancer | MTT assay | IC50 = 3.3 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-Leu | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7/ADM | Breast Cancer | MTT assay | IC50 = 4.4 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Leu | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562 | Leukemia cancer | MTT assay | IC50 = 1.1 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-Val | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562 | Leukemia cancer | MTT assay | IC50 = 5.0 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-Leu | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7 | Breast Cancer | MTT assay | IC50 = 3.6 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Val | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7 | Breast Cancer | MTT assay | IC50 = 4.9 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1-Ala14 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | K-562 | Leukemia cancer | MTT assay | IC50 = 8.6 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1-Ala14 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Synthetic analog of B1 | MCF-7 | Breast Cancer | MTT assay | IC50 = 8.9 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Cathelicidin-BF15 | MCF-7/ADM | Breast Cancer | MTT assay | IC50 = 24.1 µM | 24-h | Breast | None | ||
| 25462264 | 2015 | B1 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Cathelicidin-BF15 | K-562/ADM | Leukemia cancer | MTT assay | IC50 = 31.6 µM | 24-h | Blood | None | ||
| 25462264 | 2015 | B1 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Cathelicidin-BF15 | K-562 | Leukemia cancer | MTT assay | IC50 = 26.9 µM | 24-h | Blood | None | ||
| 27486068 | 2015 | Lipotetrapeptide-C16-PCatPCatPCatPCat-NH2 | 4 | Linear | L | Pcat = L-4R-aminoproline ; Phex = L-4R-hexyloxyproline | Amidation | Palmitic acid | Anticancer | Synthetic | DU-145 | Prostate Cancer | MTS assay | CC50 = 16.5 µM | 73-76h | Prostate | None | ||
| 27486068 | 2015 | Lipotetrapeptide-C16-PCatPCatPCatPCat-NH2 | 4 | Linear | L | Pcat = L-4R-aminoproline ; Phex = L-4R-hexyloxyproline | Amidation | Palmitic acid | Anticancer | Synthetic | MiaPaCa.2 | Pancreatic Cancer | MTS assay | CC50 = 23 µM | 73-76h | Pancreas | None | ||
| 25462264 | 2015 | B1 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Cathelicidin-BF15 | MCF-7 | Breast Cancer | MTT assay | IC50 = 21.9 µM | 24-h | Breast | None | ||
| 27486068 | 2015 | C16-Lipotetrapeptide | 4 | Linear | L | None | Amidation | Palmitic acid | Anticancer | Synthetic | DU-145 | Prostate Cancer | MTS assay | CC50 = 18 µM | 73-76h | Prostate | None | ||
| 27486068 | 2015 | Lipotetrapeptide-C16-PCatPCatPCatPCat-NH2 | 4 | Linear | L | Pcat = L-4R-aminoproline ; Phex = L-4R-hexyloxyproline | Amidation | Palmitic acid | Anticancer | Synthetic | MDA-MB-231 | Breast Cancer | MTS assay | CC50 = 12.5 µM | 73-76h | Breast | None | ||
| 27486068 | 2015 | Lipotetrapeptide-C16-PCatPCatPCatPCat-NH2 | 4 | Linear | L | Pcat = L-4R-aminoproline ; Phex = L-4R-hexyloxyproline | Amidation | Palmitic acid | Anticancer | Synthetic | JIMT-1 | Breast Cancer | MTS assay | CC50 = 17 µM | 73-76h | Breast | None | ||
| 27486068 | 2015 | C16-Liptotripeptide | 3 | Linear | L | None | Amidation | Palmitic acid | Anticancer | Synthetic | MiaPaCa.2 | Pancreatic Cancer | MTS assay | CC50 =16 µM | 73-76h | Pancreas | None | ||
| 27486068 | 2015 | C16-Lipotetrapeptide | 4 | Linear | L | None | Amidation | Palmitic acid | Anticancer | Synthetic | MDA-MB-231 | Breast Cancer | MTS assay | CC50 = 30 µM | 73-76h | Breast | None | ||
| 27486068 | 2015 | C16-Lipotetrapeptide | 4 | Linear | L | None | Amidation | Palmitic acid | Anticancer | Synthetic | JIMT-1 | Breast Cancer | MTS assay | CC50 = 30 µM | 73-76h | Breast | None | ||
| 27486068 | 2015 | C14-Liptotripeptide | 3 | Linear | L | None | Amidation | Myristic acid | Anticancer | Synthetic | DU-145 | Prostate Cancer | MTS assay | CC50 =10 µM | 73-76h | Prostate | None | ||
| 27486068 | 2015 | C16-Liptotripeptide | 3 | Linear | L | None | Amidation | Palmitic acid | Anticancer | Synthetic | JIMT-1 | Breast Cancer | MTS assay | CC50 = 10 µM | 73-76h | Breast | None | ||
| 27486068 | 2015 | C16-Liptotripeptide | 3 | Linear | L | None | Amidation | Palmitic acid | Anticancer | Synthetic | DU-145 | Prostate Cancer | MTS assay | CC50 = 9 µM | 73-76h | Prostate | None | ||
| 25447543 | 2015 | Human neutrophil peptide-1 (HNP-1) | 30 | Cyclic(C2-C30, C4-C19,C9-C29) | L | None | Free | Free | Antimicrobial | Homo sapiens | PC-3 | Prostate Cancer | Cytotoxicity assay (LIVE/DEAD® Viability/Cytotoxicity Assay Kit (L-3224)) | IC50 = 2.2 ± 0.3 μM | 4h | Prostate | None | ||
| 25633717 | 2015 | KEMTUB10 | 4 | Linear | L | None | fluorine atom in para-position on the phenyl ring | N-tubuvaline fragment replaced with stable benzyl group | Anti-cancer | Synthetic analogue of natural tubulysins | MDA-MB-453 | Breast Cancer | MTT assay | IC50 = 16.3 ± 5.6 pM | 72-h | Breast | None | ||
| 25633717 | 2015 | KEMTUB10 | 4 | Linear | L | None | fluorine atom in para-position on the phenyl ring | N-tubuvaline fragment replaced with stable benzyl group | Anti-cancer | Synthetic analogue of natural tubulysins | SK-BR-3 | Breast Cancer | MTT assay | IC50 = 12.2 ± 6 pM | 72-h | Breast | None | ||
| 25633717 | 2015 | KEMTUB10 | 4 | Linear | L | None | fluorine atom in para-position on the phenyl ring | N-tubuvaline fragment replaced with stable benzyl group | Anti-cancer | Synthetic analogue of natural tubulysins | MCF-7/DD | Breast Cancer | MTT assay | IC50 = 68.6 ± 30.1 pM | 72-h | Breast | None | ||
| 25633717 | 2015 | KEMTUB10 | 4 | Linear | L | None | fluorine atom in para-position on the phenyl ring | N-tubuvaline fragment replaced with stable benzyl group | Anti-cancer | Synthetic analogue of natural tubulysins | MDA-MB-231 | Breast Cancer | MTT assay | IC50 = 68 ± 18 pM | 72-h | Breast | None | ||
| 25633717 | 2015 | KEMTUB10 | 4 | Linear | L | None | fluorine atom in para-position on the phenyl ring | N-tubuvaline fragment replaced with stable benzyl group | Anti-cancer | Synthetic analogue of natural tubulysins | MCF-7 | Breast Cancer | MTT assay | IC50 = 30.1 ± 13.2 pM | 72-h | Breast | US 8,580,820; US (US 2011/200581). | ||
| 26482932 | 2015 | Cytotoxin-II | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | HL-60 | Leukemia Cancer | LDH leakage assay | IC50 = 23.01 μg/mL | 24-h | Blood | None | ||
| 26482932 | 2015 | Cytotoxin-II | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | DU-145 | Prostrate Cancer | LDH leakage assay | IC50 = 15.91 μg/mL | 24-h | Prostate | None | ||
| 26482932 | 2015 | Cytotoxin-II | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | HepG-2 | Liver Cancer | LDH leakage assay | IC50 = 28.99 μg/mL | 24-h | Liver | None | ||
| 26482932 | 2015 | Cytotoxin-II | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | MCF-7 | Breast Cancer | LDH leakage assay | IC50 = 23.9 μg/mL | 24-h | Breast | None | ||
| 26482932 | 2015 | Cytotoxin-II | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | HL-60 | Leukemia Cancer | MTT assay | IC50 < 20 μg/mL | 24-h | Blood | None | ||
| 26482932 | 2015 | Cytotoxin-II | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | DU-145 | Prostrate Cancer | MTT assay | IC50 ~ 15 μg/mL | 24-h | Prostate | None | ||
| 26482932 | 2015 | Cytotoxin-II | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | HepG-2 | Liver Cancer | MTT assay | IC50 ~ 20 μg/mL | 24-h | Liver | None | ||
| 26482932 | 2015 | Cytotoxin-II | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | MCF-7 | Breast Cancer | MTT assay | IC50 ~ 10 μg/mL | 24-h | Breast | None | ||
| 26482932 | 2015 | Cytotoxin-I | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | HL-60 | Leukemia Cancer | LDH leakage assay | IC50 = 38.3 μg/mL | 24-h | Blood | None | ||
| 26482932 | 2015 | Cytotoxin-I | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | DU-145 | Prostrate Cancer | LDH leakage assay | IC50 = 20.99 μg/mL | 24-h | Prostate | None | ||
| 26482932 | 2015 | Cytotoxin-I | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | HepG-2 | Liver Cancer | LDH leakage assay | IC50 = 35.84 μg/mL | 24-h | Liver | None | ||
| 26482932 | 2015 | Cytotoxin-I | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | MCF-7 | Breast Cancer | LDH leakage assay | IC50 = 45.71 μg/mL | 24-h | Breast | None | ||
| 26482932 | 2015 | Cytotoxin-I | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | HL-60 | Leukemia Cancer | MTT assay | IC50 < 40 μg/mL | 24-h | Blood | None | ||
| 26482932 | 2015 | Cytotoxin-I | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | DU-145 | Prostrate Cancer | MTT assay | IC50 ~ 20 μg/mL | 24-h | Prostate | None | ||
| 26482932 | 2015 | Cytotoxin-I | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | HepG-2 | Liver Cancer | MTT assay | IC50 ~ 40 μg/mL | 24-h | Liver | None | ||
| 26482932 | 2015 | Cytotoxin-I | 60 | Cyclic | L | None | Free | Free | Anticancer | Caspian cobra (Naja oxiana) venom | MCF-7 | Breast Cancer | MTT assay | IC50 < 20 μg/mL | 24-h | Breast | None | ||
| 25821084 | 2015 | Ep-AMP1 | 35 | Cyclic | L | None | Cyclized | Cyclized | Antibacterial and Anticancer | Echinopsis pachanoi | U-937/GTB | Lymphoma cancer | Fluorometric microculture cytotoxicity assay | IC50 > 100 µM | Not Available | Blood | None | ||
| 26322745 | 2015 | Cyclotide mela-6 | 29 | Cyclic | L | None | Cyclized | Cyclized | Antibacterial and Anticancer | Melicytus latifolius | HeLa | Cervical Cancer | Resazurin dye assay | CC50 = 11.42 ±1.00 µM | Not Available | Cervix | None | ||
| 26322745 | 2015 | Cyclotide mela-6 | 29 | Cyclic | L | None | Cyclized | Cyclized | Antibacterial and Anticancer | Melicytus latifolius | MM96L | Skin Cancer | Resazurin dye assay | CC50 = 1.58 ±0.48 µM | Not Available | Skin | None | ||
| 26399495 | 2015 | Mra30 | 30 | Cyclic | L | None | Cyclized | Cyclized | Antimicrobial and Anticancer | Viola tricolor, Melicytus ramiflorus, Viola philippica | BGC-823 | Gastric Cancer | Resazurin dye assay | IC50 = 1.75 ±0.05 µM | Not Available | Stomach | None | ||
| 26399495 | 2015 | Mra30 | 30 | Cyclic | L | None | Cyclized | Cyclized | Antimicrobial and Anticancer | Viola tricolor, Melicytus ramiflorus, Viola philippica | HeLa | Cervical Cancer | Resazurin dye assay | IC50 = 15.5 ±0.06 µM | Not Available | Cervix | None | ||
| 26399495 | 2015 | Mra30 | 30 | Cyclic | L | None | Cyclized | Cyclized | Antimicrobial and Anticancer | Viola tricolor, Melicytus ramiflorus, Viola philippica | MM96L | Skin Cancer | Resazurin dye assay | IC50 = 4.91 ±0.04 µM | Not Available | Skin | None | ||
| 26322745 | 2015 | Mela3 | 29 | Cyclic | L | None | Cyclized | Cyclized | Antibacterial and Anticancer | Melicytus latifolius | HeLa | Cervical Cancer | Resazurin dye assay | CC50 = 18.73 ±1.82 µM | Not Available | Cervix | None | ||
| 25974307 | 2015 | IturinA | 7 | Cyclic | L | None | Cyclized; C16 Fatty acid moiety | Cyclized | Lipopeptide | Bacillus megaterium | MDA-MB-468 | Breast Cancer | MTT assay | IC50 = 13.30 ± 0.97 μM | 48-h | Breast | None | ||
| 26322745 | 2015 | Mela3 | 29 | Cyclic | L | None | Cyclized | Cyclized | Antibacterial and Anticancer | Melicytus latifolius | MM96L | Skin Cancer | Resazurin dye assay | CC50 = 2.04 ±0.26 µM | Not Available | Skin | None | ||
| 25974307 | 2015 | IturinA | 7 | Cyclic | L | None | Cyclized; C16 Fatty acid moiety | Cyclized | Lipopeptide | Bacillus megaterium | MDA-MB-231 | Breast Cancer | MTT assay | IC50 = 7.98 ± 0.19 μM | 48-h | Breast | None | ||
| 25974307 | 2015 | IturinA | 7 | Cyclic | L | None | Cyclized; C16 Fatty acid moiety | Cyclized | Lipopeptide | Bacillus megaterium | MCF-7 | Breast Cancer | MTT assay | IC50 = 12.16 ± 0.24 μM | 48-h | Breast | None | ||
| 25974307 | 2015 | IturinA | 7 | Cyclic | L | None | Cyclized; C16 Fatty acid moiety | Cyclized | Lipopeptide | Bacillus megaterium | T-47D | Breast Cancer | MTT assay | IC50 = 26.29 ± 0.78 μM | 48-h | Breast | None | ||
| 26703631 | 2015 | Pardaxin | 33 | Linear | L | None | Free | Free | Antimicrobial | Pardachirus marmoratus | OSCC-SCC-4 | Oral cancer | MTT assay | Cell Viability <20% at 20μg/mL | 24-h | Not Available | None | ||
| 25626077 | 2015 | AaeAP2a | 19 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic analog of AaeAP2 | MCF-7 | Breast Cancer | MTT assay | Graph Figure 4 | 24-h | Breast | None | ||
| 25626077 | 2015 | AaeAP2a | 19 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic analog of AaeAP2 | PC-3 | Prostate Cancer | MTT assay | Graph Figure 4 | 24-h | Prostate | None | ||
| 25626077 | 2015 | AaeAP2a | 19 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic analog of AaeAP2 | MDA-MB-435S | Skin Cancer | MTT assay | Graph Figure 4 | 24-h | Skin | None | ||
| 25626077 | 2015 | AaeAP1a | 19 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic analog of AaeAP1 | MCF-7 | Breast Cancer | MTT assay | Graph Figure 4 | 24-h | Breast | None | ||
| 25626077 | 2015 | AaeAP1a | 19 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic analog of AaeAP1 | PC-3 | Prostate Cancer | MTT assay | Graph Figure 4 | 24-h | Prostate | None | ||
| 25626077 | 2015 | AaeAP1a | 19 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic analog of AaeAP1 | MDA-MB-435S | Skin Cancer | MTT assay | Graph Figure 4 | 24-h | Skin | None | ||
| 26751970 | 2015 | Vigno 5 | 29 | Cyclic(C5-C19,C9-C21,C14-C21) | L | None | Free | Free | Anticancer | Viola ignobilis | HeLa | Cervical Cancer | MTT assay | 24% cell viability at 7.5 μM | 24-h | Cervix | None | ||
| 26064310 | 2015 | DC1 | 32 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | DU-145 | Liver Cancer | CCK-8 assay | IC50 = 3.32 μM | 72-h | Liver | None | ||
| 26064310 | 2015 | DC1 | 32 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | PC-3 | Prostate Cancer | CCK-8 assay | IC50 = 2.24 μM | 72-h | Prostate | None | ||
| 26064310 | 2015 | DC1 | 32 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | LNCaP | Prostate Cancer | CCK-8 assay | IC50 = 5.03 μM | 72-h | Prostate | None | ||
| 26064310 | 2015 | DC2 | 31 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | DU-145 | Liver Cancer | CCK-8 assay | IC50 = 3.11 μM | 72-h | Liver | None | ||
| 26064310 | 2015 | DC2 | 31 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | PC-3 | Prostate Cancer | CCK-8 assay | IC50 = 2.65 μM | 72-h | Prostate | None | ||
| 26064310 | 2015 | DC2 | 31 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | LNCaP | Prostate Cancer | CCK-8 assay | IC50 = 4.31 μM | 72-h | Prostate | None | ||
| 26064310 | 2015 | DC3 | 30 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | DU-145 | Liver Cancer | CCK-8 assay | IC50 = 0.55 μM | 72-h | Liver | None | ||
| 26064310 | 2015 | DC3 | 30 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | PC-3 | Prostate Cancer | CCK-8 assay | IC50 = 0.76 μM | 72-h | Prostate | None | ||
| 26064310 | 2015 | DC3 | 30 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | LNCaP | Prostate Cancer | CCK-8 assay | IC50 = 0.21 μM | 72-h | Prostate | None | ||
| 26402731 | 2015 | Chaxapeptin | 15 | Mix | L | None | Free | Cyclized to form macrolactam ring | Antimicrobial and Anticancer | Streptomyces leeuwenhoekii Strain C58 | A-549 | Lung Cancer | CyQUANT Direct assay | Cell invasion < 50% at 50 μM | 36-h | Lung | None | ||
| 25047444 | 2015 | CopA3 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | analogue derived from coprisin | SNU-668 | Gastric cancer | LDH release assay | Cytotoxicity ~ 60-80% at 50 μM | 24-h | Stomach | None | ||
| 25047444 | 2015 | CopA3 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | analogue derived from coprisin | SNU-638 | Gastric cancer | LDH release assay | Cytotoxicity ~ 60-80% at 50 μM | 24-h | Stomach | None | ||
| 25047444 | 2015 | CopA3 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | analogue derived from coprisin | SNU-601 | Gastric cancer | LDH release assay | Cytotoxicity ~ 60-80% at 50 μM | 24-h | Stomach | None | ||
| 25047444 | 2015 | CopA3 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | analogue derived from coprisin | SNU-484 | Gastric cancer | LDH release assay | Cytotoxicity ~ 60-80% at 50 μM | 24-h | Stomach | None | ||
| 25047444 | 2015 | CopA3 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | analogue derived from coprisin | SNU-668 | Gastric cancer | MTS assay | IC50 ~ 20-50 μM | 24-h | Stomach | None | ||
| 25047444 | 2015 | CopA3 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | analogue derived from coprisin | SNU-638 | Gastric cancer | MTS assay | IC50 ~ 20-50 μM | 24-h | Stomach | None | ||
| 25047444 | 2015 | CopA3 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | analogue derived from coprisin | SNU-601 | Gastric cancer | MTS assay | IC50 ~ 20-50 μM | 24-h | Stomach | None | ||
| 25047444 | 2015 | CopA3 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | analogue derived from coprisin | SNU-484 | Gastric cancer | MTS assay | IC50 ~ 20-50 μM | 24-h | Stomach | None | ||
| 26405806 | 2015 | HPRP-A1-TAT | 24 | Linear | L | None | Amidation | Acetylation | Anticancer | Synthetic | HeLa | Cervical Cancer | MTT assay | IC50 = 1.8 ± 0.02 μM | 24-h | Cervix | None | ||
| 26405806 | 2015 | HPRP-A1-TAT | 24 | Linear | L | None | Amidation | Acetylation | Anticancer | Synthetic | B-16 | Skin Cancer | MTT assay | IC50 = 3.9 ± 0.02 μM | 24-h | Skin | None | ||
| 26405806 | 2015 | HPRP-A1-TAT | 24 | Linear | L | None | Amidation | Acetylation | Anticancer | Synthetic | HepG-2 | Liver Cancer | MTT assay | IC50 = 5.8 ± 0.36 μM | 24-h | Liver | None | ||
| 26405806 | 2015 | HPRP-A1-TAT | 24 | Linear | L | None | Amidation | Acetylation | Anticancer | Synthetic | SGC-7901 | Gastric cancer | MTT assay | IC50 = 4.8 ± 0.08 μM | 24-h | Stomach | None | ||
| 26405806 | 2015 | HPRP-A1 | 15 | Linear | L | None | Amidation | Acetylation | Anticancer | Helicobacter pylori | HeLa | Cervical Cancer | MTT assay | IC50 = 3.5 ± 0.03 μM | 24-h | Cervix | None | ||
| 26405806 | 2015 | HPRP-A1 | 15 | Linear | L | None | Amidation | Acetylation | Anticancer | Helicobacter pylori | HepG-2 | Liver Cancer | MTT assay | IC50 = 7.7 ± 0.23 μM | 24-h | Liver | None | ||
| 26405806 | 2015 | HPRP-A1 | 15 | Linear | L | None | Amidation | Acetylation | Anticancer | Helicobacter pylori | SGC-7901 | Gastric cancer | MTT assay | IC50 = 5.2 ± 0.14 μM | 24-h | Stomach | None | ||
| 26405806 | 2015 | HPRP-A1 | 15 | Linear | L | None | Amidation | Acetylation | Anticancer | Helicobacter pylori | B-16 | Skin Cancer | MTT assay | IC50 = 6.1 ± 0.02 μM | 24-h | Skin | None | ||
| 26239537 | 2015 | RW-AH | 18 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | SBcl2 | Skin Cancer | MTS assay | LC50 = 4.6 ± 0.2 μM | 24-h | Skin | None | ||
| 26239537 | 2015 | RW-AH | 18 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | A-375 | Skin Cancer | MTS assay | LC50 = 8.4 ± 0.5 μM | 24-h | Skin | None | ||
| 26239537 | 2015 | RW-AH | 18 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | A-375 | Skin Cancer | PI uptake assay | LC50 = 4.5 ± 0.02 μM | 8-h | Skin | None | ||
| 26239537 | 2015 | DIM-LF11-318 | 22 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | SBcl2 | Skin Cancer | MTS assay | LC50 = 9.4 ± 0.5 μM | 24-h | Skin | None | ||
| 26239537 | 2015 | DIM-LF11-318 | 22 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | A-375 | Skin Cancer | MTS assay | LC50 = 9.3 ± 0.8 μM | 24-h | Skin | None | ||
| 26239537 | 2015 | DIM-LF11-318 | 22 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | A-375 | Skin Cancer | PI uptake assay | LC50 = 3.8 ± 0.5 μM | 8-h | Skin | None | ||
| 26239537 | 2015 | R-DIM-LF11-337 | 22 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | SBcl2 | Skin Cancer | MTS assay | LC50 = 5.0 ± 0.4 μM | 24-h | Skin | None | ||
| 26239537 | 2015 | R-DIM-LF11-337 | 22 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | A-375 | Skin Cancer | MTS assay | LC50 = 12.3 ± 1.3 μM | 24-h | Skin | None | ||
| 26239537 | 2015 | R-DIM-LF11-337 | 22 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | A-375 | Skin Cancer | PI uptake assay | LC50 = 3.5 ± 0.4 μM | 8-h | Skin | None | ||
| 26239537 | 2015 | R-DIM-P-LF11-322 | 19 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | SBcl2 | Skin Cancer | MTS assay | LC50 = 10.4 ± 0.7 μM | 24-h | Skin | EP_2943215_B1 | ||
| 26239537 | 2015 | R-DIM-P-LF11-322 | 19 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | A-375 | Skin Cancer | MTS assay | LC50 = 23.3 ± 1.7 μM | 24-h | Skin | EP_2943215_B1 | ||
| 26239537 | 2015 | R-DIM-P-LF11-322 | 19 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | SBcl2 | Skin Cancer | PI uptake assay | LC50 = 5.9 ± 0.3 μM | 8-h | Skin | EP_2943215_B1 | ||
| 26239537 | 2015 | R-DIM-P-LF11-322 | 19 | Linear | L | None | Amidation | Free | Host Defence Peptide | Synthetic | A-375 | Skin Cancer | PI uptake assay | LC50 = 9.5 ± 0.3 μM | 8-h | Skin | EP_2943215_B1 | ||
| 25970292 | 2015 | K6-Nal2-S1 | 18 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | SAS | Oral Cancer | MTT assay | Graph Figure 2 | 24-h | Tongue | None | ||
| 25970292 | 2015 | K6-Nal2-S1 | 18 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | OECM-1 | Oral Cancer | MTT assay | Graph Figure 2 | 24-h | Not Available | None | ||
| 25970292 | 2015 | K6-Nal2-S1 | 18 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | C9 | Oral Cancer | MTT assay | Graph Figure 2 | 24-h | Not Available | None | ||
| 25970292 | 2015 | K6-Nal2-S1 | 18 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | A-549 | Lung Cancer | MTT assay | Graph Figure 2 | 24-h | Lung | None | ||
| 25970292 | 2015 | K6-Nal2-S1 | 18 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | PC-9G | Lung Cancer | MTT assay | Graph Figure 2 | 24-h | Lung | None | ||
| 25970292 | 2015 | K6-Nal2-S1 | 18 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | PC-9 | Lung Cancer | MTT assay | Graph Figure 2 | 24-h | Lung | None | ||
| 25970292 | 2015 | K4R2-Nal2-S1 | 18 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | SAS | Oral Cancer | MTT assay | Graph Figure 2 | 24-h | Tongue | None | ||
| 25970292 | 2015 | K4R2-Nal2-S1 | 18 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | OECM-1 | Oral Cancer | MTT assay | Graph Figure 2 | 24-h | Not Available | None | ||
| 25970292 | 2015 | K4R2-Nal2-S1 | 18 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | C9 | Oral Cancer | MTT assay | Graph Figure 2 | 24-h | Not Available | None | ||
| 25970292 | 2015 | K4R2-Nal2-S1 | 18 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | A-549 | Lung Cancer | MTT assay | Graph Figure 2 | 24-h | Lung | None | ||
| 25970292 | 2015 | K4R2-Nal2-S1 | 18 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | PC-9G | Lung Cancer | MTT assay | Graph Figure 2 | 24-h | Lung | None | ||
| 25970292 | 2015 | K4R2-Nal2-S1 | 18 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | PC-9 | Lung Cancer | MTT assay | Graph Figure 2 | 24-h | Lung | None | ||
| 25970292 | 2015 | Nal2-S1 | 12 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | SAS | Oral Cancer | MTT assay | Graph Figure 2 | 24-h | Tongue | US_10093699_B2 | ||
| 25970292 | 2015 | Nal2-S1 | 12 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | OECM-1 | Oral Cancer | MTT assay | Graph Figure 2 | 24-h | Not Available | US_10093699_B2 | ||
| 25970292 | 2015 | Nal2-S1 | 12 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | C9 | Oral Cancer | MTT assay | Graph Figure 2 | 24-h | Not Available | US_10093699_B2 | ||
| 25970292 | 2015 | Nal2-S1 | 12 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | A-549 | Lung Cancer | MTT assay | Graph Figure 2 | 24-h | Lung | US_10093699_B2 | ||
| 25970292 | 2015 | Nal2-S1 | 12 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | PC-9G | Lung Cancer | MTT assay | Graph Figure 2 | 24-h | Lung | US_10093699_B2 | ||
| 25970292 | 2015 | Nal2-S1 | 12 | Linear | L | Nal = beta-naphthylalanine | Amidation | Acetylation | Antimicrobial | Synthetic | PC-9 | Lung Cancer | MTT assay | Graph Figure 2 | 24-h | Lung | US_10093699_B2 | ||
| 25312253 | 2014 | E5 | 22 | Linear | L | None | Free | Free | Anticancer | Synthetic | U-937 | Leukemia Cancer | FITC-Annexin V/PI double staining and flow cytometry assay | >20% apoptosis rate at 80 μM | 24-h | Blood | None | ||
| 25312253 | 2014 | E5 | 22 | Linear | L | None | Free | Free | Anticancer | Synthetic | HL-60 | Leukemia Cancer | FITC-Annexin V/PI double staining and flow cytometry assay | >20% apoptosis rate at 80 μM | 24-h | Blood | None | ||
| 25312253 | 2014 | E5 | 22 | Linear | L | None | Free | Free | Anticancer | Synthetic | NB-4 | Leukemia Cancer | FITC-Annexin V/PI double staining and flow cytometry assay | 60% apoptosis rate at 80 μM | 24-h | Blood | None | ||
| 24692446 | 2014 | NaD1 | 47 | Cyclic(C3-C47,C14-34,C20-C41,C24-C43) | L | None | None | None | Host Defense | Nicotiana alata | B16-F10 | Skin Cancer | MTT assay | IC50 = 1.5 ± 0.6 μM | 48-h | Skin | None | ||
| 24692446 | 2014 | NaD1 | 47 | Cyclic(C3-C47,C14-34,C20-C41,C24-C43) | L | None | None | None | Host Defense | Nicotiana alata | HeLa | Cervical Cancer | MTT assay | IC50 = 1.0 ± 0.1 μM | 48-h | Cervix | None | ||
| 24692446 | 2014 | NaD1 | 47 | Cyclic(C3-C47,C14-34,C20-C41,C24-C43) | L | None | None | None | Host Defense | Nicotiana alata | MM170 | Skin Cancer | MTT assay | IC50 = 2.4 ± 0.8 μM | 48-h | Skin | None | ||
| 24692446 | 2014 | NaD1 | 47 | Cyclic(C3-C47,C14-34,C20-C41,C24-C43) | L | None | None | None | Host Defense | Nicotiana alata | MCF-7 | Breast Cancer | MTT assay | IC50 = 2.0 ± 1.3 μM | 48-h | Breast | None | ||
| 24692446 | 2014 | NaD1 | 47 | Cyclic(C3-C47,C14-34,C20-C41,C24-C43) | L | None | None | None | Host Defense | Nicotiana alata | HCT-116 | Colon Cancer | MTT assay | IC50 = 4.9 ± 3.1 μM | 48-h | Colon | None | ||
| 24503375 | 2014 | Cyclosaplin | 8 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Santalum album L | MDA-MB-231 | Breast Cancer | MTT assay | IC50 = 2.06 μg/mL | 24-h | Breast | 638/KOL/2013 | ||
| 24692199 | 2014 | Baceridin | 6 | Cyclic | Mix | None | Cyclized | Cyclized | Antimicrobial and Anticancer | culture medium of a plant-associated Bacillus strain | HeLa | Cervical Cancer | MTT assay | IC50 between (1–2 µg/mL) | 72-h | Cervix | None | ||
| 24692199 | 2014 | Baceridin | 6 | Cyclic | Mix | None | Cyclized | Cyclized | Antimicrobial and Anticancer | culture medium of a plant-associated Bacillus strain | RKO | Colon Cancer | MTT assay | IC50 between (1–2 µg/mL) | 72-h | Colon | None | ||
| 24692199 | 2014 | Baceridin | 6 | Cyclic | Mix | None | Cyclized | Cyclized | Antimicrobial and Anticancer | culture medium of a plant-associated Bacillus strain | HCT-116 -/- p53 | Colon Cancer | MTT assay | IC50 between (1–2 µg/mL) | 72-h | Colon | None | ||
| 24704757 | 2014 | Frenatin 2.1S | 16 | Linear | L | None | alpha-amidation | Free | Antimicrobial | Sphaenorhynchus lacteus | A-549 | Lung Cancer | Trypan blue assay | LC50 = 80 ± 6 μM | 24-h | Lung | None | ||
| 24704757 | 2014 | Frenatin 2.2S | 16 | Linear | L | None | alpha-amidation | Free | Antimicrobial | Sphaenorhynchus lacteus | A-549 | Lung Cancer | Trypan blue assay | LC50 = 75 ± 5 μM | 24-h | Lung | None | ||
| 24492520 | 2014 | Gageostatin C | 7 | Linear | L | None | Free | (E)-7,9-dimethylundec-2-enoic acid | Antimicrobial | Bacillus subtilis | ACHN | Renal Cancer | Sulforhodamine B assay | GI50 = 12.3 µg/mL | 48-h | Kidney | None | ||
| 24492520 | 2014 | Gageostatin C | 7 | Linear | L | None | Free | (E)-7,9-dimethylundec-2-enoic acid | Antimicrobial | Bacillus subtilis | NCI-H23 | Lung Cancer | Sulforhodamine B assay | GI50 = 10.9 µg/mL | 48-h | Lung | None | ||
| 24492520 | 2014 | Gageostatin C | 7 | Linear | L | None | Free | (E)-7,9-dimethylundec-2-enoic acid | Antimicrobial | Bacillus subtilis | NUGC-3 | Stomach Cancer | Sulforhodamine B assay | GI50 = 10.5 µg/mL | 48-h | Stomach | None | ||
| 24492520 | 2014 | Gageostatin C | 7 | Linear | L | None | Free | (E)-7,9-dimethylundec-2-enoic acid | Antimicrobial | Bacillus subtilis | HCT-15 | Colon Cancer | Sulforhodamine B assay | GI50 = 23.2 µg/mL | 48-h | Colon | None | ||
| 24492520 | 2014 | Gageostatin C | 7 | Linear | L | None | Free | (E)-7,9-dimethylundec-2-enoic acid | Antimicrobial | Bacillus subtilis | PC-3 | Prostate Cancer | Sulforhodamine B assay | GI50 = 11.7 µg/mL | 48-h | Prostate | None | ||
| 24492520 | 2014 | Gageostatin B | 7 | Linear | L | None | Free | 3-beta-hydroxy-9,11-dimethyltridecanoic acid | Antimicrobial | Bacillus subtilis | ACHN | Renal Cancer | Sulforhodamine B assay | GI50 = 18.4 µg/mL | 48-h | Kidney | None | ||
| 24492520 | 2014 | Gageostatin C | 7 | Linear | L | None | Free | (E)-7,9-dimethylundec-2-enoic acid | Antimicrobial | Bacillus subtilis | MDA-MB-231 | Breast Cancer | Sulforhodamine B assay | GI50 = 11.2 µg/mL | 48-h | Breast | None | ||
| 24492520 | 2014 | Gageostatin B | 7 | Linear | L | None | Free | 3-beta-hydroxy-9,11-dimethyltridecanoic acid | Antimicrobial | Bacillus subtilis | NUGC-3 | Stomach Cancer | Sulforhodamine B assay | GI50 = 13.9 µg/mL | 48-h | Stomach | None | ||
| 24492520 | 2014 | Gageostatin B | 7 | Linear | L | None | Free | 3-beta-hydroxy-9,11-dimethyltridecanoic acid | Antimicrobial | Bacillus subtilis | PC-3 | Prostate Cancer | Sulforhodamine B assay | GI50 = 19.4 µg/mL | 48-h | Prostate | None | ||
| 24492520 | 2014 | Gageostatin B | 7 | Linear | L | None | Free | 3-beta-hydroxy-9,11-dimethyltridecanoic acid | Antimicrobial | Bacillus subtilis | NCI-H23 | Lung Cancer | Sulforhodamine B assay | GI50 = 11.7 µg/mL | 48-h | Lung | None | ||
| 24492520 | 2014 | Gageostatin B | 7 | Linear | L | None | Free | 3-beta-hydroxy-9,11-dimethyltridecanoic acid | Antimicrobial | Bacillus subtilis | MDA-MB-231 | Breast Cancer | Sulforhodamine B assay | GI50 = 16.1 µg/mL | 48-h | Breast | None | ||
| 24492520 | 2014 | Gageostatin B | 7 | Linear | L | None | Free | 3-beta-hydroxy-9,11-dimethyltridecanoic acid | Antimicrobial | Bacillus subtilis | HCT-15 | Colon Cancer | Sulforhodamine B assay | GI50 = 18.3 µg/mL | 48-h | Colon | None | ||
| 24492520 | 2014 | Gageostatin A | 7 | Linear | L | None | Free | 3-beta-hydroxy-11-methyltridecanoic acid | Antimicrobial | Bacillus subtilis | ACHN | Renal Cancer | Sulforhodamine B assay | GI50 = 11.5 µg/mL | 48-h | Kidney | None | ||
| 24492520 | 2014 | Gageostatin A | 7 | Linear | L | None | Free | 3-beta-hydroxy-11-methyltridecanoic acid | Antimicrobial | Bacillus subtilis | NCI-H23 | Lung Cancer | Sulforhodamine B assay | GI50 = 11.2 µg/mL | 48-h | Lung | None | ||
| 24492520 | 2014 | Gageostatin A | 7 | Linear | L | None | Free | 3-beta-hydroxy-11-methyltridecanoic acid | Antimicrobial | Bacillus subtilis | NUGC-3 | Stomach Cancer | Sulforhodamine B assay | GI50 = 11.8 µg/mL | 48-h | Stomach | None | ||
| 24492520 | 2014 | Gageostatin A | 7 | Linear | L | None | Free | 3-beta-hydroxy-11-methyltridecanoic acid | Antimicrobial | Bacillus subtilis | PC-3 | Prostate Cancer | Sulforhodamine B assay | GI50 = 10.8 µg/mL | 48-h | Prostate | None | ||
| 24492520 | 2014 | Gageostatin A | 7 | Linear | L | None | Free | 3-beta-hydroxy-11-methyltridecanoic acid | Antimicrobial | Bacillus subtilis | HCT-15 | Colon Cancer | Sulforhodamine B assay | GI50 = 11.4 µg/mL | 48-h | Colon | None | ||
| 24492520 | 2014 | Gageostatin A | 7 | Linear | L | None | Free | 3-beta-hydroxy-11-methyltridecanoic acid | Antimicrobial | Bacillus subtilis | MDA-MB-231 | Breast Cancer | Sulforhodamine B assay | GI50 = 14.9 µg/mL | 48-h | Breast | None | ||
| 24830845 | 2014 | mt_S20A/L22 W/P27A | 12 | Linear | L | None | Free | Free | Anticancer | MDM5 | MCF-7 | Breast Cancer | MTT/MTS assay | IC50= 8.7 µM | Not Available | Breast | None | ||
| 24830845 | 2014 | mt_T18S/L22 W/P27A | 12 | Linear | L | None | Free | Free | Anticancer | MDM4 | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=27 µM | Not Available | Breast | None | ||
| 24830845 | 2014 | mt_E17L/L22 W/P27A | 12 | Linear | L | None | Free | Free | Anticancer | MDM3 | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=15.1 µM | Not Available | Breast | None | ||
| 24830845 | 2014 | mt_L22 W/P27A | 12 | Linear | L | None | Free | Free | Anticancer | MDM2 | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=16.3 µM | Not Available | Breast | None | ||
| 24714081 | 2014 | T Peptide | 19 | Linear | L | None | Free | Free | Anticancer | Tuftsin derivative | BGC-823 | Gastric Cancer | MTT/MTS assay | 67.2% maximum inhibitory rate at 8 mg/kg | 48-h | Stomach | None | ||
| 24714081 | 2014 | T Peptide | 19 | Linear | L | None | Free | Free | Anticancer | Tuftsin derivative | HT-29 | Colon Cancer | MTT/MTS assay | 70% maximum inhibitory rate at 8 mg/kg | 48-h | Colon | None | ||
| 24714081 | 2014 | T Peptide | 19 | Linear | L | None | Free | Free | Anticancer | Tuftsin derivative | HepG-2 | Liver Cancer | MTT/MTS assay | 69.6% maximum inhibitory rate at 8 mg/kg | 48-h | Liver | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC107 | Colorectal Cancer | Cell Viability assay | Cell viability >70% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC107 | Colorectal Cancer | Cell Viability assay | Cell viability >65% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC107 | Colorectal Cancer | Cell Viability assay | Cell viability >50% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC32 | Colorectal Cancer | Cell Viability assay | Cell viability >85% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC32 | Colorectal Cancer | Cell Viability assay | Cell viability >80% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC32 | Colorectal Cancer | Cell Viability assay | Cell viability >55% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC113 | Colorectal Cancer | Cell Viability assay | Cell viability >70% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC113 | Colorectal Cancer | Cell Viability assay | Cell viability >65% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC113 | Colorectal Cancer | Cell Viability assay | Cell viability >80% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC60 | Colorectal Cancer | Cell Viability assay | Cell viability >70% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC60 | Colorectal Cancer | Cell Viability assay | Cell viability >60% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC60 | Colorectal Cancer | Cell Viability assay | Cell viability >70% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC40 | Colorectal Cancer | Cell Viability assay | Cell viability >85% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC40 | Colorectal Cancer | Cell Viability assay | Cell viability >80% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC40 | Colorectal Cancer | Cell Viability assay | Cell viability >45% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC24 | Colorectal Cancer | Cell Viability assay | Cell viability >70% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC24 | Colorectal Cancer | Cell Viability assay | Cell viability >55% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC24 | Colorectal Cancer | Cell Viability assay | Cell viability >55% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC18 | Colorectal Cancer | Cell Viability assay | Cell viability >75% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC18 | Colorectal Cancer | Cell Viability assay | Cell viability >55% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC18 | Colorectal Cancer | Cell Viability assay | Cell viability >55% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HCT-116 | Colorectal Cancer | Cell Viability assay | Cell viability >50% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HCT-116 | Colorectal Cancer | Cell Viability assay | Cell viability >40% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HCT-116 | Colorectal Cancer | Cell Viability assay | Cell viability >40% at 12.5μM approx | 24-h | Colon | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC32 | Colorectal Cancer | Cell Viability assay | Cell viability =50% at 12.5μM approx. | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC32 | Colorectal Cancer | Cell Viability assay | Cell viability =50% at 12.5μM approx. | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC32 | Colorectal Cancer | Cell Viability assay | Cell viability >60% at 25μM approx | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC60 | Colorectal Cancer | Cell Viability assay | Cell viability >50% at 25μM approx | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC60 | Colorectal Cancer | Cell Viability assay | Cell viability >50% at 25μM approx | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC60 | Colorectal Cancer | Cell Viability assay | Cell viability >50% at 25μM approx | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC40 | Colorectal Cancer | Cell Viability assay | Cell viability >50% at 25μM approx | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC40 | Colorectal Cancer | Cell Viability assay | Cell viability >50% at 25μM approx | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC40 | Colorectal Cancer | Cell Viability assay | Cell viability >60% at 25μM approx | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC24 | Colorectal Cancer | Cell Viability assay | Cell viability >60% at 25μM approx | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC24 | Colorectal Cancer | Cell Viability assay | Cell viability >50% at 25μM approx | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HROC24 | Colorectal Cancer | Cell Viability assay | Cell viability >60% at 25μM approx | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A-Δ | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HCT-116 | Colorectal Cancer | Cell Viability assay | Cell viability >50% at 12.5μM approx. | 1-h | Colon | None | ||
| 24962950 | 2014 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HCT-116 | Colorectal Cancer | Cell Viability assay | Cell viability =50% at 12.5μM approx. | 1-h | Colon | None | ||
| 24676901 | 2014 | LTX-328 | 8 | Linear | L | Dip = diphenylalanine | Amidation | Free | Antimicrobial | Synthetic peptide | Fem-X | Skin Cancer | MTT/MTS assay | IC50= >350 µM | 5–60 Min | Skin | None | ||
| 24962950 | 2014 | C7A | 27 | Linear | L | None | Amidation | Free | Antitumor | NK-2 peptide based derivatives | HCT-116 | Colorectal Cancer | Cell Viability assay | Cell viability >50% at 25μM approx | 1-h | Colon | None | ||
| 24676901 | 2014 | LTX-315 | 9 | Linear | L | Dip = diphenylalanine | Amidation | Free | Antimicrobial | Synthetic peptide | A375 | Skin Cancer | MTT/MTS assay | IC50=12.7 µM | 30-Min | Skin | None | ||
| 24676901 | 2014 | LTX-315 | 9 | Linear | L | Dip = diphenylalanine | Amidation | Free | Antimicrobial | Synthetic peptide | Fem-X | Skin Cancer | MTT/MTS assay | IC50=15.3 µM | 30-Min | Skin | None | ||
| 24676901 | 2014 | LTX-315 | 9 | Linear | L | Dip = diphenylalanine | Amidation | Free | Antimicrobial | Synthetic peptide | B16F1 | Skin Cancer | MTT/MTS assay | IC50=13.3 µM | 30-Min | Skin | None | ||
| 24661024 | 2014 | Melittin | 26 | Linear | L | None | Free | Free | Antimicrobial | Main component of honey bee venom | SCC25 | Skin Cancer | Cell Viability assay | 102.9 ± 4.1% cell growth inhibition at 1 µM | 24-h | Skin | None | ||
| 24661024 | 2014 | Cecropin A | 37 | Linear | L | None | Free | Free | Antimicrobial | Isolated from the giant silk moth Hyalophora cecropia | SCC25 | Skin Cancer | Cell Viability assay | 107.0 ± 5.0% cell growth inhibition at 1 µM | 24-h | Skin | None | ||
| 24661024 | 2014 | Cecropin A | 37 | Linear | L | None | Free | Free | Antimicrobial | Isolated from the giant silk moth Hyalophora cecropia | SCC25 | Skin Cancer | Cell Viability assay | 0.6 ± 0.6% cell growth inhibition at 10 µM | 48-h | Skin | None | ||
| 24661024 | 2014 | Cecropin A | 37 | Linear | L | None | Free | Free | Antimicrobial | Isolated from the giant silk moth Hyalophora cecropia | SCC25 | Skin Cancer | MTT/MTS assay | IC50=2.2 µM | 48-h | Skin | None | ||
| 24661024 | 2014 | Cecropin A | 37 | Linear | L | None | Free | Free | Antimicrobial | Isolated from the giant silk moth Hyalophora cecropia | SCC12 | Skin Cancer | MTT/MTS assay | IC50=1 µM | 48-h | Skin | None | ||
| 24587350 | 2014 | LL 37 | 37 | Linear | L | None | Free | Free | Antimicrobial | Also known human cathelicidin | OVRCAR-3 | Ovarian Cancer | MTT/MTS assay | LC50= 24 at 100 µM | 72-h | Ovary | None | ||
| 24587350 | 2014 | Pexiganan | 22 | Linear | L | None | Amidation | Free | Antimicrobial | Analog of magainin 2 | OVRCAR-3 | Ovarian Cancer | MTT/MTS assay | LC50= 13 at 100 µM | 72-h | Ovary | None | ||
| 24587350 | 2014 | LL 37 | 37 | Linear | L | None | Free | Free | Antimicrobial | Also known human cathelicidin | LNCaP | Prostate cancer | MTT/MTS assay | LC50= 27 at 100 µM | 72-h | Prostate | None | ||
| 24587350 | 2014 | Pexiganan | 22 | Linear | L | None | Amidation | Free | Antimicrobial | Analog of magainin 2 | LNCaP | Prostate cancer | MTT/MTS assay | LC50= 6 at 100 µM | 72-h | Prostate | None | ||
| 24587350 | 2014 | LL 37 | 37 | Linear | L | None | Free | Free | Antimicrobial | Also known human cathelicidin | MCF-7 | Breast Cancer | MTT/MTS assay | LC50= 21 at 100 µM | 72-h | Breast | None | ||
| 24587350 | 2014 | Pexiganan | 22 | Linear | L | None | Amidation | Free | Antimicrobial | Analog of magainin 2 | MCF-7 | Breast Cancer | MTT/MTS assay | LC50= 8 at 100 µM | 72-h | Breast | None | ||
| 22885172 | 2012 | ltc2aG11A | 26 | Linear | L | None | Free | Free | Antimicrobial | Central Asian spider, Lachesana tarabaevi | Prostate tumor cellline | Prostate Cancer | LDH leakage assay | graph fig 8 A | Not Available | Prostate | None | ||
| 23085771 | 2012 | 12c | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=14 µM | Not Available | Blood | None | ||
| 22885172 | 2012 | Latarcin 2a | 26 | Linear | L | None | Free | Free | Antimicrobial | Central Asian spider, Lachesana tarabaevi | Breast tumor cellline | Breast Cancer | LDH leakage assay | graph fig 8 A | Not Available | Breast | None | ||
| 23085771 | 2012 | 12a | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=6.1 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 12b | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=27 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 11b | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=19 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 11c | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=7.2 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 11a | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=5.2 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 10b | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=11.4 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 10c | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=6.6 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 9c | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=3.1 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 10a | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=28 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 9a | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=31 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 9b | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=2.3 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 8b | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=>254 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 8c | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=107 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 8a | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=136 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 7b | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=>78 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 7c | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=79 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 6c | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=4.3 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 7a | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=>63 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 5c | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=4.1 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 6a | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=14.4 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 6b | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=11.0 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 5a | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=10.6 µM | Not Available | Blood | None | ||
| 23085771 | 2012 | 5b | 3 | Linear | L | None | Free | Free | Antimicrobial | synthetic b2,2-amino acid derivatives | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50=7.1 µM | Not Available | Blood | None | ||
| 21351323 | 2011 | EGFR-lytic | 32 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | MDA-MB-231 | Breast Cancer | ELISA | IC50 =0.46 µM | 15-Min | Breast | None | ||
| 21351323 | 2011 | EGFR-lytic | 32 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | MDA-MB-231 | Breast Cancer | ELISA | IC50 =0.12 µM | 60-Min | Breast | None | ||
| 21403917 | 2011 | Temporin A | 13 | Linear | L | None | Amidation | Free | Antimicrobial | Frog Rana temporaria | U-943 | Lymphoma Cancer | MTT/MTS assay | IC50 =80-90 µg/ml | Not Available | Blood | None | ||
| 21403917 | 2011 | Protegrin 1 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | alpha helical peptide without cysteines | U-942 | Lymphoma Cancer | MTT/MTS assay | IC50 =30-40 µg/ml | Not Available | Blood | None | ||
| 21403917 | 2011 | Pexiganan MSI-78 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | Analog of Magainin | U-941 | Lymphoma Cancer | MTT/MTS assay | IC50 =20-30 µg/ml | Not Available | Blood | None | ||
| 21403917 | 2011 | Omiganan MBI-226 | 12 | Linear | L | None | Amidation | Free | Antimicrobial | Bovine neutrophils | U-937 | Lymphoma Cancer | MTT/MTS assay | IC50 =80-85 µg/ml | Not Available | Blood | None | ||
| 21403917 | 2011 | Demegen P-113 | 12 | Linear | L | None | Amidation | Free | Antimicrobial | Canaida albicans | U-939 | Lymphoma Cancer | MTT/MTS assay | IC50 =85-90 µg/ml | Not Available | Blood | None | ||
| 21403917 | 2011 | Citropin 1.1 | 16 | Linear | L | None | Amidation | Free | Antimicrobial | Australian blue mountains tree frog, Litoria citropa | U-938 | Lymphoma Cancer | MTT/MTS assay | IC50 =40 µg/ml | Not Available | Blood | None | ||
| 21403917 | 2011 | Buforin 2 | 21 | Linear | L | None | Free | Free | Antimicrobial | Bufo Bufo Gargarizans | U-937 | Lymphoma Cancer | MTT/MTS assay | IC50 =90-95 µg/ml | Not Available | Blood | None | ||
| 21423613 | 2011 | P5317-28 | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 =30 µM | Not Available | Colon | None | ||
| 21423613 | 2011 | 3A | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 >100 µM | Not Available | Colon | None | ||
| 21423613 | 2011 | MIP | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 =0.12 µM | Not Available | Colon | None | ||
| 21423613 | 2011 | DI | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 =1.6 µM | Not Available | Colon | None | ||
| 21423613 | 2011 | MIP(M11A) | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 =0.4 µM | Not Available | Colon | None | ||
| 21423613 | 2011 | MIP(R9A) | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 =0.02 µM | Not Available | Colon | None | ||
| 21423613 | 2011 | MIP(L10A) | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 =1.14 µM | Not Available | Colon | None | ||
| 21423613 | 2011 | MIP(W7A) | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 >100 µM | Not Available | Colon | None | ||
| 21423613 | 2011 | MIP(Y6A) | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 >100 µM | Not Available | Colon | None | ||
| 21423613 | 2011 | MIP(F3A) | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 =0.57 µM | Not Available | Colon | None | ||
| 21423613 | 2011 | 3A | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 >100 µM | Not Available | Colon | None | ||
| 21423613 | 2011 | P5317-28 | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 =4.7 µM | Not Available | Colon | None | ||
| 21423613 | 2011 | DI | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 =0.29 µM | Not Available | Colon | None | ||
| 21928125 | 2012 | p776 | 15 | Linear | L | None | Free | Free | Antitumor | Synthetic Peptide | Not Available | Tumor | ELISPOT assay | Not Available | Not Available | Not Available | None | ||
| 21423613 | 2011 | MIP | 12 | Linear | L | None | Free | Free | Antitumor | E3 ubiquitin-protein ligase | HCT-116-p53+/+ | Colon Cancer | Immunoprecipitation assay | IC50 =0.01 µM | Not Available | Colon | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MCF-7-TX400 | Breast Cancer | MTT/MTS assay | ~5% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 21928125 | 2012 | p85 | 10 | Linear | L | None | Free | Free | Antitumor | Synthetic Peptide | Not Available | Tumor | ELISPOT assay | Not Available | Not Available | Not Available | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MCF-7-TX400 | Breast Cancer | MTT/MTS assay | 60-70% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MCF-7 | Breast Cancer | MTT/MTS assay | 70% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MCF-7 | Breast Cancer | MTT/MTS assay | 0% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MCF-7-TX400 | Breast Cancer | MTT/MTS assay | 60-70% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | 4T1 | Breast Cancer | MTT/MTS assay | ~0% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | 4T1 | Breast Cancer | MTT/MTS assay | 5-10% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | 4T1 | Breast Cancer | MTT/MTS assay | 20% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MCF-7 | Breast Cancer | MTT/MTS assay | 70% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-468 | Breast Cancer | MTT/MTS assay | 5% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-468 | Breast Cancer | MTT/MTS assay | 10-15% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | 4T1 | Breast Cancer | MTT/MTS assay | ~0% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | SKBR-3 | Breast Cancer | MTT/MTS assay | 15-20% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-468 | Breast Cancer | MTT/MTS assay | ~5% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-468 | Breast Cancer | MTT/MTS assay | ~5% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | SKBR-3 | Breast Cancer | MTT/MTS assay | 10% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | SKBR-3 | Breast Cancer | MTT/MTS assay | 10-15% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | T-47D | Breast Cancer | MTT/MTS assay | 10-15% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | SKBR-3 | Breast Cancer | MTT/MTS assay | 10% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | T-47D | Breast Cancer | MTT/MTS assay | ~0% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | T-47D | Breast Cancer | MTT/MTS assay | 10% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-231 | Breast Cancer | MTT/MTS assay | 10% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-231 | Breast Cancer | MTT/MTS assay | 10-15% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | T-47D | Breast Cancer | MTT/MTS assay | ~0% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | 4T1 | Breast Cancer | MTT/MTS assay | 80-90% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | 4T1 | Breast Cancer | MTT/MTS assay | 85-90% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-13 | 23 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-231 | Breast Cancer | MTT/MTS assay | ~5% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-468 | Breast Cancer | MTT/MTS assay | 80-90% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | 4T1 | Breast Cancer | MTT/MTS assay | 30-40% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | 4T1 | Breast Cancer | MTT/MTS assay | 60-70% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-468 | Breast Cancer | MTT/MTS assay | 50% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-468 | Breast Cancer | MTT/MTS assay | 80% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-468 | Breast Cancer | MTT/MTS assay | 10% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | SKBR-3 | Breast Cancer | MTT/MTS assay | 20% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | SKBR-3 | Breast Cancer | MTT/MTS assay | 70-80% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | SKBR-3 | Breast Cancer | MTT/MTS assay | 80-85% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | T-47D | Breast Cancer | MTT/MTS assay | 40-50% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | SKBR-3 | Breast Cancer | MTT/MTS assay | ~0% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | T-47D | Breast Cancer | MTT/MTS assay | 20% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-231 | Breast Cancer | MTT/MTS assay | 40-50% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | T-47D | Breast Cancer | MTT/MTS assay | ~0% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | T-47D | Breast Cancer | MTT/MTS assay | 10% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-231 | Breast Cancer | MTT/MTS assay | 5% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-231 | Breast Cancer | MTT/MTS assay | 20-30% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | 4T1 | Breast Cancer | MTT/MTS assay | 85-90% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-07 | 25 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-231 | Breast Cancer | MTT/MTS assay | ~0% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | 4T1 | Breast Cancer | MTT/MTS assay | 40-50% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | 4T1 | Breast Cancer | MTT/MTS assay | 80% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-468 | Breast Cancer | MTT/MTS assay | 60-70% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-468 | Breast Cancer | MTT/MTS assay | 80-85% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | 4T1 | Breast Cancer | MTT/MTS assay | 15-20% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-468 | Breast Cancer | MTT/MTS assay | 40-50% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | SKBR-3 | Breast Cancer | MTT/MTS assay | 70% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | SKBR-3 | Breast Cancer | MTT/MTS assay | 80-85% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-468 | Breast Cancer | MTT/MTS assay | 30% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | SKBR-3 | Breast Cancer | MTT/MTS assay | 50% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | T-47D | Breast Cancer | MTT/MTS assay | 60% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | SKBR-3 | Breast Cancer | MTT/MTS assay | 30% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | T-47D | Breast Cancer | MTT/MTS assay | 30-35% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | T-47D | Breast Cancer | MTT/MTS assay | 5-10% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | T-47D | Breast Cancer | MTT/MTS assay | 10% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-231 | Breast Cancer | MTT/MTS assay | 60% cytotoxic at 50 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-231 | Breast Cancer | MTT/MTS assay | 5% cytotoxic at 5 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-231 | Breast Cancer | MTT/MTS assay | 5% cytotoxic at 10 µM | 24-h | Breast | None | ||
| 22023734 | 2011 | NRC-03 | 26 | Linear | L | None | Amidation | Biotinylated | Antimicrobial | Pleurocidin-family | MDA-MB-231 | Breast Cancer | MTT/MTS assay | 30-35% cytotoxic at 25 µM | 24-h | Breast | None | ||
| 22057278 | 2011 | Z10 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | HT-29 | Colon Cancer | MTT/MTS assay | EC50 >211 µM | Not Available | Colon | None | ||
| 22057278 | 2011 | Z9 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | HT-29 | Colon Cancer | MTT/MTS assay | EC50 =13 µM | Not Available | Colon | None | ||
| 22057278 | 2011 | Z7 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | HT-29 | Colon Cancer | MTT/MTS assay | EC50 =21 µM | Not Available | Colon | None | ||
| 22057278 | 2011 | Z8 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | HT-29 | Colon Cancer | MTT/MTS assay | EC50 =23 µM | Not Available | Colon | None | ||
| 22057278 | 2011 | Z6 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | HT-29 | Colon Cancer | MTT/MTS assay | EC50 =31 µM | Not Available | Colon | None | ||
| 22057278 | 2011 | Z5 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | HT-29 | Colon Cancer | MTT/MTS assay | EC50 =67 µM | Not Available | Colon | None | ||
| 22057278 | 2011 | Z4 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | HT-29 | Colon Cancer | MTT/MTS assay | EC50 =173 µM | Not Available | Colon | None | ||
| 22057278 | 2011 | Z3 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | HT-29 | Colon Cancer | MTT/MTS assay | EC50 >211 µM | Not Available | Colon | None | ||
| 22057278 | 2011 | Z2 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | HT-29 | Colon Cancer | MTT/MTS assay | EC50 >211 µM | Not Available | Colon | None | ||
| 22057278 | 2011 | Z1 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | HT-29 | Colon Cancer | MTT/MTS assay | EC50 >211 µM | Not Available | Colon | None | ||
| 22057278 | 2011 | Z10 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | MT-1 | Breast Cancer | MTT/MTS assay | EC50 >211 µM | Not Available | Breast | None | ||
| 22057278 | 2011 | Z9 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | MT-1 | Breast Cancer | MTT/MTS assay | EC50 =16 µM | Not Available | Breast | None | ||
| 22057278 | 2011 | Z8 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | MT-1 | Breast Cancer | MTT/MTS assay | EC50 =14 µM | Not Available | Breast | None | ||
| 22057278 | 2011 | Z7 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | MT-1 | Breast Cancer | MTT/MTS assay | EC50 =15 µM | Not Available | Breast | None | ||
| 22057278 | 2011 | Z6 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | MT-1 | Breast Cancer | MTT/MTS assay | EC50 =16 µM | Not Available | Breast | None | ||
| 22057278 | 2011 | Z5 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | MT-1 | Breast Cancer | MTT/MTS assay | EC50 =28 µM | Not Available | Breast | None | ||
| 22057278 | 2011 | Z4 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | MT-1 | Breast Cancer | MTT/MTS assay | EC50 =68 µM | Not Available | Breast | None | ||
| 22057278 | 2011 | Z3 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | MT-1 | Breast Cancer | MTT/MTS assay | EC50 =128 µM | Not Available | Breast | None | ||
| 22057278 | 2011 | Z2 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | MT-1 | Breast Cancer | MTT/MTS assay | EC50 =173 µM | Not Available | Breast | None | ||
| 22057278 | 2011 | Z1 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | MT-1 | Breast Cancer | MTT/MTS assay | EC50 =186 µM | Not Available | Breast | None | ||
| 22057278 | 2011 | Z10 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | Meth A | Skin Cancer | MTT/MTS assay | EC50 >211 µM | Not Available | Skin | None | ||
| 22057278 | 2011 | Z9 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | Meth A | Skin Cancer | MTT/MTS assay | EC50 =9 µM | Not Available | Skin | None | ||
| 22057278 | 2011 | Z8 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | Meth A | Skin Cancer | MTT/MTS assay | EC50 =19 µM | Not Available | Skin | None | ||
| 22057278 | 2011 | Z7 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | Meth A | Skin Cancer | MTT/MTS assay | EC50 =15 µM | Not Available | Skin | None | ||
| 22057278 | 2011 | Z6 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | Meth A | Skin Cancer | MTT/MTS assay | EC50 =17 µM | Not Available | Skin | None | ||
| 22057278 | 2011 | Z5 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | Meth A | Skin Cancer | MTT/MTS assay | EC50 =42 µM | Not Available | Skin | None | ||
| 22057278 | 2011 | Z4 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | Meth A | Skin Cancer | MTT/MTS assay | EC50 =155 µM | Not Available | Skin | None | ||
| 22057278 | 2011 | Z3 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | Meth A | Skin Cancer | MTT/MTS assay | EC50 >211 µM | Not Available | Skin | None | ||
| 22057278 | 2011 | Z2 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | Meth A | Skin Cancer | MTT/MTS assay | EC50 >211 µM | Not Available | Skin | None | ||
| 22057278 | 2011 | Z1 | 21 | Linear | L | None | Free | Free | Anticancer | Synthetic | Meth A | Skin Cancer | MTT/MTS assay | EC50 >211 µM | Not Available | Skin | None | ||
| 22076954 | 2011 | Peptide-3 | 11 | Linear | L | Pem= Pemetrexed | Amidation | Free | Anticancer | Synthetic | NCI-H358 | Lung Cancer | MTT/MTS assay | IC50 = 8.41 µM | 3-h | Lung | None | ||
| 22076954 | 2011 | Peptide-2 | 20 | Linear | L | Pem= Pemetrexed | Amidation | Free | Anticancer | Synthetic | NCI-H358 | Lung Cancer | MTT/MTS assay | IC50 = 2.19 µM | 3-h | Lung | None | ||
| 22076954 | 2011 | Peptide-1 | 10 | Linear | L | Pem= Pemetrexed | Amidation | Free | Anticancer | Synthetic | NCI-H358 | Lung Cancer | MTT/MTS assay | IC50 = 4.63 mM | 3-h | Lung | None | ||
| 22076954 | 2011 | Peptide-3 | 11 | Linear | L | Pem= Pemetrexed | Amidation | Free | Anticancer | Synthetic | HL-60 | Leukemia Cancer | MTT/MTS assay | IC50 = 6.24 µM | 3-h | Blood | None | ||
| 22076954 | 2011 | Peptide-2 | 10 | Linear | L | Pem= Pemetrexed | Amidation | Free | Anticancer | Synthetic | HL-60 | Leukemia Cancer | MTT/MTS assay | IC50 = 2.64 µM | 3-h | Blood | None | ||
| 22076954 | 2011 | Peptide-1 | 10 | Linear | L | Pem= Pemetrexed | Amidation | Free | Anticancer | Synthetic | HL-60 | Leukemia Cancer | MTT/MTS assay | IC50 = 2.17 µM | 3-h | Blood | None | ||
| 21434649, 18957441 | 2011 | Vaby D | 30 | Not Available | L | None | Free | Free | Anticancer | African, the Ethiopian highlands, Viola abyssinica | Not Available | Fibrosarcoma | Not Available | Not Available | Not Available | Fibrous connective tissue | None | ||
| 21434649, 18957441 | 2011 | Vaby A | 29 | Not Available | L | None | Free | Free | Anticancer | African, the Ethiopian highlands, Viola abyssinica | Not Available | Fibrosarcoma | Not Available | Not Available | Not Available | Fibrous connective tissue | None | ||
| 22771617, 18957441 | 2012 | Maculatin 1.3 | 21 | Not Available | L | None | Free | Free | Anticancer | Blue-thighed frog,Litoria chloris, Australia | Not Available | Skin Cancer | Not Available | Not Available | Not Available | Not Available | None | ||
| 22771617, 18957441 | 2012 | Maculatin 1.4 | 21 | Not Available | L | None | Free | Free | Anticancer | Blue-thighed frog,Litoria chloris, Australia | Not Available | Skin Cancer | Not Available | Not Available | Not Available | Not Available | None | ||
| 22100226, 18957441 | 2012 | Macropin 1 | 13 | Not Available | L | None | Free | Free | Antibacterial | Venom, the solitary beeMacropis fulvipes | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 22100226, 18957441 | 2012 | Macropin 2 | 17 | Not Available | L | None | Free | Free | Antibacterial | Venom, the solitary beeMacropis fulvipes | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21596752, 18957441 | 2011 | Cliotide T2 | 30 | Not Available | L | None | Free | Free | Antibacterial | Clitoria ternatea | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21596752, 18957441 | 2011 | Cliotide T4 | 30 | Not Available | L | None | Free | Free | Antibacterial | Clitoria ternatea | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21596752, 18957441 | 2011 | Cliotide T1 | 30 | Not Available | L | None | Free | Free | Antibacterial | Clitoria ternatea | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21596752, 18957441 | 2011 | Cliotide T3 | 29 | Not Available | L | None | Free | Free | Antibacterial | Clitoria ternatea | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21723349, 18957441 | 2011 | Viphi G | 31 | Not Available | L | None | Free | Free | Antibacterial | Viola philippica | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21723349, 18957441 | 2011 | Viba17 | 29 | Not Available | L | None | Free | Free | Antibacterial | Viola philippica | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21723349, 18957441 | 2011 | Viba 15 | 29 | Not Available | L | None | Free | Free | Antibacterial | Viola philippica | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21723349, 18957441 | 2011 | Mram 8 | 30 | Not Available | L | None | Free | Free | Antibacterial | Viola philippica | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21723349, 18957441 | 2011 | Viphi F | 31 | Not Available | L | None | Free | Free | Antibacterial | Viola philippica | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21723349, 18957441 | 2011 | Viphi F | 31 | Not Available | L | None | Free | Free | Antibacterial | Viola philippica | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21723349, 18957441 | 2011 | Viphi E | 31 | Not Available | L | None | Free | Free | Antibacterial | Viola philippica | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 22467870, 18957441 | 2012 | Chassatide C2 | 32 | Not Available | L | None | Free | Free | Antibacterial | Chassalia chartacea | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 22467870, 18957441 | 2012 | Chassatide C10 | 29 | Not Available | L | None | Free | Free | Antibacterial | Chassalia chartacea | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 22467870, 18957441 | 2012 | Chassatide C4 | 29 | Not Available | L | None | Free | Free | Antibacterial | Chassalia chartacea | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 22467870, 18957441 | 2012 | Chassatide C4 | 29 | Not Available | L | None | Free | Free | Antibacterial | Chassalia chartacea | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 22467870, 18957441 | 2012 | ChaC11 | 29 | Not Available | L | None | Free | Free | Antibacterial | Chassalia chartacea | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 22467870, 18957441 | 2012 | Chassatide C8 | 29 | Not Available | L | None | Free | Free | Antibacterial | Chassalia chartacea | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 22467870, 18957441 | 2012 | ChaC7 | 29 | Not Available | L | None | Free | Free | Antibacterial | Chassalia chartacea | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21882228, 18957441 | 2012 | Cr-ACP1 | 9 | Not Available | L | None | Free | Free | Antibacterial | Seeds,Cycas revoluta | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 23034893 | 2012 | AAD (or Aa-Pri1) | 145 | Linear | L | None | Free | Free | Antitumor | Purified from Agrocybe aegerita | SH-SY5Y | Brain Tumor | MTT/MTS assay | At 2.5 µM concentration,decrease in cell vibility= 70% | 48-h | Brain | None | ||
| 23034893 | 2012 | AAD (or Aa-Pri1) | 145 | Linear | L | None | Free | Free | Antitumor | Purified from Agrocybe aegerita | HeLa | Cervical Cancer | MTT/MTS assay | At 2.5 µM concentration,decrease in cell vibility= 70% | 48-h | Cervix | None | ||
| 23034893 | 2012 | AAD (or Aa-Pri1) | 145 | Linear | L | None | Free | Free | Antitumor | Purified from Agrocybe aegerita | HepG-2 | Liver Cancer | MTT/MTS assay | At 2.5 µM concentration,decrease in cell vibility= 35% | 48-h | Liver | None | ||
| 22963485 | 2012 | RGD-mda-7 | 207 | Linear | L | None | Free | Free | Anticancer | Derived from wtmda-7/IL-24 by insertion og a glycine residue between Arg(164) and Asp(165). | Ket-3 | Tumor | MTT assay | Apoptotic rate(%)= >50% at concentration of 8 µg/ml | 72-h | Not Available | None | ||
| 22963485 | 2012 | RGD-mda-7 | 207 | Linear | L | None | Free | Free | Anticancer | Derived from wtmda-7/IL-24 by insertion og a glycine residue between Arg(164) and Asp(165). | MCF-7 | Breast Cancer | MTT assay | Apoptotic rate(%)= >70% at concentration of 8 µg/ml | 72-h | Breast | None | ||
| 22963485 | 2012 | wtmda-7/IL-24 | 206 | Linear | L | None | Free | Free | Anticancer | NA | Ket-3 | Tumor | MTT assay | Apoptotic rate(%)= >30% at concentration of 8 µg/ml | 72-h | Not Available | None | ||
| 22963485 | 2012 | wtmda-7/IL-24 | 206 | Linear | L | None | Free | Free | Anticancer | NA | MCF-7 | Breast Cancer | MTT assay | Apoptotic rate(%)= >50% at concentration of 8 µg/ml | 72-h | Breast | None | ||
| 22963485 | 2012 | RGD-mda-7 | 207 | Linear | L | None | Free | Free | Anticancer | Derived from wtmda-7/IL-24 by insertion og a glycine residue between Arg(164) and Asp(165). | Ket-3 | Tumor | MTT/MTS assay | Cell viability(% of control)= 0.5 at concentration 8 µg/ml | 48-h | Not Available | None | ||
| 22963485 | 2012 | RGD-mda-7 | 207 | Linear | L | None | Free | Free | Anticancer | Derived from wtmda-7/IL-24 by insertion og a glycine residue between Arg(164) and Asp(165). | MCF-7 | Breast Cancer | MTT/MTS assay | Cell viability(% of control)=0.5 at concentration 4 µg/ml | 48-h | Breast | None | ||
| 22963485 | 2012 | wtmda-7/IL-24 | 206 | Linear | L | None | Free | Free | Anticancer | NA | Ket-3 | Tumor | MTT/MTS assay | Cell viability(% of control)= 0.5 at concentration 8 µg/ml | 48-h | Not Available | None | ||
| 22963485 | 2012 | wtmda-7/IL-24 | 206 | Linear | L | None | Free | Free | Anticancer | NA | MCF-7 | Breast Cancer | MTT/MTS assay | Cell viability(% of control)=0.5 at concentration 7 µg/ml | 48-h | Breast | None | ||
| 23893605 | 2013 | Melittin | 26 | Linear | L | None | Amidation | Free | Anticancer | Natural component of bee venom | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 1.4±0.1 µM | 24-h | Skin | None | ||
| 23893605 | 2013 | NK-11 | 11 | Linear | L | None | Amidation | Free | Anticancer | NK2 derived inactive control peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 >> 100 µM | 24-h | Skin | None | ||
| 23893605 | 2013 | C7A- Δ | 23 | Linear | L | None | Amidation | Free | Anticancer | NK-2 variants | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 13.1±0.9 µM | 24-h | Skin | None | ||
| 23893605 | 2013 | C7A-D21k | 27 | Linear | L | None | Amidation | Free | Anticancer | NK-2 variants | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 12.3±1.0 µM | 24-h | Skin | None | ||
| 23893605 | 2013 | C7A | 27 | Linear | L | None | Amidation | Free | Anticancer | NK-2 variants | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 3.7± 4.3 µM | 24-h | Skin | None | ||
| 23893605 | 2013 | NK-2 | 27 | Linear | L | None | Amidation | Free | Anticancer | Residue of 39-65 of porcine NK-lysine | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 40 µM (approx) | 24-h | Skin | None | ||
| 23893605 | 2013 | NK-11 | 11 | Linear | L | None | Amidation | Free | Anticancer | NK2 derived inactive control peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC-50 >> 100 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | Melittin | 26 | Linear | L | None | Amidation | Free | Anticancer | Natural component of bee venom | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 1.8±0.1 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | C7A- Δ | 23 | Linear | L | None | Amidation | Free | Anticancer | NK-2 variants | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 9.3±1.5 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | C7A-D21k | 27 | Linear | L | None | Amidation | Free | Anticancer | NK-2 variants | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 8.3±0.5 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | C7A | 27 | Linear | L | None | Amidation | Free | Anticancer | NK-2 variants | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 12.1±1.6 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | NK-2 | 27 | Linear | L | None | Amidation | Free | Anticancer | Residue of 39-65 of porcine NK-lysine | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 50 µM (approx) | 4-h | Skin | None | ||
| 23893605 | 2013 | Melittin | 26 | Linear | L | None | Amidation | Free | Anticancer | Natural component of bee venom | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 2.1±0.1 µM | 2-h | Skin | None | ||
| 23893605 | 2013 | NK-11 | 11 | Linear | L | None | Amidation | Free | Anticancer | NK2 derived inactive control peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC-50 >> 100 µM | 2-h | Skin | None | ||
| 23893605 | 2013 | C7A- Δ | 23 | Linear | L | None | Amidation | Free | Anticancer | NK-2 variants | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 13.8±2.0 µM | 2-h | Skin | None | ||
| 23893605 | 2013 | C7A-D21k | 27 | Linear | L | None | Amidation | Free | Anticancer | NK-2 variants | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 12.3±2.0 µM | 2-h | Skin | None | ||
| 23893605 | 2013 | C7A | 27 | Linear | L | None | Amidation | Free | Anticancer | NK-2 variants | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 13.0±1.0 µM | 2-h | Skin | None | ||
| 23893605 | 2013 | NK-2 | 27 | Linear | L | None | Amidation | Free | Anticancer | Residue of 39-65 of porcine NK-lysine | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 50 µM (approx) | 2-h | Skin | None | ||
| 23893605 | 2013 | Melittin | 26 | Linear | L | None | Amidation | Free | Anticancer | Natural component of bee venom | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 3.2±0.1 µM | 30-Min | Skin | None | ||
| 23893605 | 2013 | NK-11 | 11 | Linear | L | None | Amidation | Free | Anticancer | NK2 derived inactive control peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC-50>> 100 µM | 30-Min | Skin | None | ||
| 23893605 | 2013 | C7A- Δ | 23 | Linear | L | None | Amidation | Free | Anticancer | NK-2 variants | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 7.5±0.4 µM | 30-Min | Skin | None | ||
| 23893605 | 2013 | C7A-D21k | 27 | Linear | L | None | Amidation | Free | Anticancer | NK-2 variants | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 8.4±0.2 µM | 30-Min | Skin | None | ||
| 23893605 | 2013 | C7A | 27 | Linear | L | None | Amidation | Free | Anticancer | NK-2 variants | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 10.6±0.4 µM | 30-Min | Skin | None | ||
| 23893605 | 2013 | NK-2 | 27 | Linear | L | None | Amidation | Free | Anticancer | Residue of 39-65 of porcine NK-lysine | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 70 µM (approx) | 30-Min | Skin | None | ||
| 23893605 | 2013 | Melittin | 26 | Linear | L | None | Amidation | Free | Anticancer | Natural component of bee venom | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 1.4±0.1 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | NK-11 | 11 | Linear | L | None | Amidation | Free | Anticancer | NK2 derived inactive control peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC-50 >> 100 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | NK-2 | 27 | Linear | L | None | Amidation | Free | Anticancer | Residue of 39-65 of porcine NK-lysine | E42/02 | Skin Cancer | MTT/MTS assay | IC50= 4.3±0.3 µM | 4-h | Skin | None | ||
| 22933412 | 2012 | c8 | 5 | Linear | L | (2,2-di(4-[trifluoromethyl]benzyl)-3-amino-propionic acid) | Amidation | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 226±21 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c7 | 6 | Linear | L | (2,2-di(4-[trifluoromethyl]benzyl)-3-amino-propionic acid) | Amidation | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 157±30 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c6 | 6 | Linear | L | (2,2-di(4-[trifluoromethyl]benzyl)-3-amino-propionic acid) | Amidation | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 26±2 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c5 | 7 | Linear | L | (2,2-di(4-[trifluoromethyl]benzyl)-3-amino-propionic acid) | Amidation | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 23±3 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c4 | 5 | Linear | L | (2,2-di(naphthalen-2-ylmethyl)-3-amino-propionic acid) | Amidation | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 99±15 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c3 | 6 | Linear | L | (2,2-di(naphthalen-2-ylmethyl)-3-amino-propionic acid) | Amidation | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 92±2 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c2 | 6 | Linear | L | (2,2-di(naphthalen-2-ylmethyl)-3-amino-propionic acid) | Amidation | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 1.71±0.6 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c1 | 7 | Linear | L | (2,2-di(naphthalen-2-ylmethyl)-3-amino-propionic acid) | Amidation | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 22±5 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c8 | 5 | Cyclic | L | (2,2-di(4-[trifluoromethyl]benzyl)-3-amino-propionic acid) | Free | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 20±2 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c7 | 6 | Cyclic | L | (2,2-di(4-[trifluoromethyl]benzyl)-3-amino-propionic acid) | Free | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 16±5 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c6 | 6 | Cyclic | L | (2,2-di(4-[trifluoromethyl]benzyl)-3-amino-propionic acid) | Free | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 8±1 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c3 | 6 | Cyclic | L | (2,2-di(naphthalen-2-ylmethyl)-3-amino-propionic acid) | Free | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 15±2 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c4 | 5 | Cyclic | L | (2,2-di(naphthalen-2-ylmethyl)-3-amino-propionic acid) | Free | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 12.6±0.6 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c5 | 7 | Cyclic | L | (2,2-di(4-[trifluoromethyl]benzyl)-3-amino-propionic acid) | Free | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 11±2 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c1 | 7 | Cyclic | L | (2,2-di(naphthalen-2-ylmethyl)-3-amino-propionic acid) | Free | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 10±2 µMol/L | NA | Blood | None | ||
| 22933412 | 2012 | c2 | 6 | Cyclic | L | (2,2-di(naphthalen-2-ylmethyl)-3-amino-propionic acid) | Free | Free | Anticancer | KKWβ2,2WKK | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50= 7.9±0.3 µMol/L | NA | Blood | None | ||
| 22837667 | 2012 | Peptide L6D/L12D/L17D/L20D/L21D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 12.88±0.15 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide L6D/L12D/L17D/L20D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 9.69±0.38 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide L12D/L20D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 3.14±0.06 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide L6D/L12D/L20D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 7.80±0.26 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide L20D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 2.33±0.06 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide L6D/L12D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 3.01±0.08 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide L12D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 2.63±0.07 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide L6D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 2.23±0.10 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide K1D/K3D/K7D /K10D/K14D/K22D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 18.07±0.48 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide K7D /K10D/K14D/K22D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 4.79±0.23 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide K3D/K7D /K10D/K14D/K22D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 20.41±0.64 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide K7D /K14D/K22D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 4.45±0.19 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide K14D/K22D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 1.40±0.09 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide K7D /K14D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 2.06±0.01 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide K22D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 1.39±0.02 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide K14D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 1.52±0.05 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide K7D | 26 | Linear | Mix | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 1.29±0.03 µMol/L | 1-h | Cervix | None | ||
| 22837667 | 2012 | Peptide P | 26 | Linear | L | None | Amidation | Acetylation | Anticancer | A12L/A20L | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 1.71±0.07 µMol/L | 1-h | Cervix | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50= 22.25 µM | 72-h | Skin | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50= 12.55 µM | 72-h | Ovary | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50= 22.51 µM | 72-h | Stomach | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50= 29.10 µM | 72-h | Prostate | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | HCT-116 | Colon Cancer | MTT/MTS assay | IC50= 14.8 µM | 72-h | Colon | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | A-498 | Renal Cancer | MTT/MTS assay | IC50= 21.48 µM | 72-h | Renal | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | A-549 | Lung Cancer | MTT/MTS assay | IC50= 14.53 µM | 72-h | Lung | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50= 27.39 µM | 72-h | Skin | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50= 24.76 µM | 72-h | Ovary | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50= 47.69 µM | 72-h | Prostate | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | HCT-116 | Colon Cancer | MTT/MTS assay | IC50= 27.00 µM | 72-h | Colon | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50= 26.70 µM | 72-h | Stomach | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | A-498 | Renal Cancer | MTT/MTS assay | IC50= 41.21 µM | 72-h | Renal | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | A-549 | Lung Cancer | MTT/MTS assay | IC50= 25.20 µM | 72-h | Lung | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50= 14.58 µM | 72-h | Ovary | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50= 24.32 µM | 72-h | Prostate | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50= 13.16 µM | 72-h | Skin | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | HCT-116 | Colon Cancer | MTT/MTS assay | IC50= 14.80 µM | 72-h | Colon | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50= 13.77 µM | 72-h | Stomach | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | A-549 | Lung Cancer | MTT/MTS assay | IC50= 15.88 µM | 72-h | Lung | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50= 22.06 µM | 72-h | Ovary | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | A-498 | Renal Cancer | MTT/MTS assay | IC50= 22.59 µM | 72-h | Renal | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50= 13.97 µM | 72-h | Skin | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50= 24.31 µM | 72-h | Stomach | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50= 46.51 µM | 72-h | Prostate | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | A-549 | Lung Cancer | MTT/MTS assay | IC50= 20.36 µM | 72-h | Lung | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | HCT-116 | Colon Cancer | MTT/MTS assay | IC50= 24.63 µM | 72-h | Colon | None | ||
| 22481251 | 2012 | P7 | 11 | Linear | L | None | Free | Free | Antiproliferative and Antiangiogenic | NA | B16-F10 | Skin Cancer | WST-1 assay | IC50= 1 µM | 48-h | Skin | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Free | Free | Anticancer and Antimicrobial | Brevinin-1EMa | A-498 | Renal Cancer | MTT/MTS assay | IC50= 22.88 µM | 72-h | Renal | None | ||
| 22100226 | 2012 | HAL-2/11 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 24176852 | 2013 | KilerFLIP | 26 | linear | L | None | Free | Free | NA | NA | Jurkat | Blood Cancer | Not Available | NA | NA | Blood | None | ||
| 22100226 | 2012 | HAL-2/13 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2/24 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2/6 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2/20 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2/18 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2/19 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2/1 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2/8 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2/2 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2/22 | 12 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2/4 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/15 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 34 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/29 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/19 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/21 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/20 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/17 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/10 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/5 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/12 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/18 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/4 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/9 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 30±10 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/6 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-1/22 | 12 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2/11 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 40 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 49±9 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | HAL-2/13 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 60 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2/6 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2/24 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2/20 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2/19 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2/18 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2/8 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2/1 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2/2 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 35±5 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2/4 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 38±6 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2/22 | 12 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 35±3 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/15 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/29 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | Not tested | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/21 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/19 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/20 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/10 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 60 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/9 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 50 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/18 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 18±2 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/5 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 44±5 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/12 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/17 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2/11 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 14±3 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 44±8 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/22 | 12 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/6 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-1/4 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | SW | Colon Cancer | MTT/MTS assay | Not tested | 48-h | Colon | None | ||
| 22100226 | 2012 | HAL-2/19 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 16±4 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-2/20 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 30±5 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-2/24 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 34 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-2/6 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 23±3 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-2/13 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 13±3 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-2/2 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 6±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-2/1 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 14±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-2/8 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 15±3 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-2/18 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 14±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/29 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/15 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 14±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-2 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 12±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-2/22 | 12 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 12 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-2/4 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/19 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/21 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 30±3 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/20 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 22±3 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/10 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 13±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/17 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 35±3 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/5 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 9±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/12 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 43±14 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/18 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 4±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/9 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 9±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/4 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/6 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 15±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1 | 12 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 11±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | HAL-1/22 | 12 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Halictines and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 15±3 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/26 | 13 | Linear | L | AC6C = cyclohexyl-1-carboxylic acid | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 9±2 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/24 | 13 | Linear | L | AC6C = cyclohexyl-1-carboxylic acid | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 11 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/25 | 13 | Linear | L | AC6C = cyclohexyl-1-carboxylic acid | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 12±2 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/21 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 22±4 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/20 | 13 | Linear | L | O = Ornithine | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 25±3 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/19 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 43±11 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/10 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 16 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/16 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 70 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/9 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 14±4 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/6 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 15 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/3 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 22 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/4 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 29 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/2 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 17 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/1 | 13 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 11 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 32 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/25 | 13 | Linear | L | AC6C = cyclohexyl-1-carboxylic acid | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 14±1 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/26 | 13 | Linear | L | AC6C = cyclohexyl-1-carboxylic acid | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 18±1 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 12±6 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | MAC1/24 | 13 | Linear | L | AC6C = cyclohexyl-1-carboxylic acid | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 16±1 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/20 | 13 | Linear | L | O = Ornithine | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 35±4 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/21 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 17±2 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/19 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 68±2 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/16 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/10 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | Not tested | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/9 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 13±3 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/4 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 49±9 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/6 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 29±3 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/3 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 11±1 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/1 | 13 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 19±2 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/2 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 16 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/26 | 13 | Linear | L | AC6C = cyclohexyl-1-carboxylic acid | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 8±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 23±4 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | MAC1/24 | 13 | Linear | L | AC6C = cyclohexyl-1-carboxylic acid | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 8±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/25 | 13 | Linear | L | AC6C = cyclohexyl-1-carboxylic acid | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 7±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/20 | 13 | Linear | L | O = Ornithine | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 10±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/21 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 9±3 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/16 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 32±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/19 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 21±4 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/10 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 15±6 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/6 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 8±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/9 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 8±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/4 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 15±5 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/2 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 16±3 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/3 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 9±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1/1 | 13 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 12±4 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | MAC1 | 13 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Macropins and their analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 10±4 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/37 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50= 4±1 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/34 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 5±3 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/36 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/27 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 18 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/26 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 6 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/24 | 15 | Linear | L | O = Ornithine | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 5±2 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/25 | 15 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 4 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/23 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 6 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/22 | 15 | Linear | L | Aib = 1-amino-isobutyric acid | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 25±4 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/19 | 15 | Linear | L | Aib = 1-amino-isobutyric acid | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 8±2 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/18 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 7±2 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/17 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/16 | 15 | Linear | L | Nal = 3-(1-naphthyl)alanine | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/15 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 9±3 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/12 | 15 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 5±2 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/11 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 4±1 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/9 | 15 | Linear | L | None | Methoxylation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/10 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 9 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/8 | 15 | Linear | L | None | Free | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 9 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/4 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 18 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/6 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 6±3 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/3 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | Not tested | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/2 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 7±2 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 5±3 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/1 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | IC50 = 3±1 µM | 48-h | Blood | None | ||
| 22100226 | 2012 | LL-III/37 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 13 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/34 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 37 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/36 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | Not tested | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/27 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/25 | 15 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 20 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/26 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 30 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/24 | 15 | Linear | L | O = Ornithine | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 20 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/23 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 15 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/19 | 15 | Linear | L | Aib = 1-amino-isobutyric acid | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 28 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/22 | 15 | Linear | L | Aib = 1-amino-isobutyric acid | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 100 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/18 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | Not tested | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/17 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | Not tested | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/16 | 15 | Linear | L | Nal = 3-(1-naphthyl)alanine | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | Not tested | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/15 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 42 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/12 | 15 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 20 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/10 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | Not tested | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/11 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 48 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/9 | 15 | Linear | L | None | Methoxylation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 25± 5 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/6 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | Not tested | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/8 | 15 | Linear | L | None | Free | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | Not tested | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/4 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/2 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 11 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/3 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/1 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 12± 3 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/37 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 5±1 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | SW | Colon Cancer | MTT/MTS assay | IC50 = 18±4 µM | 48-h | Colon | None | ||
| 22100226 | 2012 | LL-III/36 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 8 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/27 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 13±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/34 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 5±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/26 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 5±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/24 | 15 | Linear | L | O = Ornithine | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 3±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/25 | 15 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 4±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/23 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 4 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/22 | 15 | Linear | L | Aib = 1-amino-isobutyric acid | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 11±7 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/18 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 3 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/19 | 15 | Linear | L | Aib = 1-amino-isobutyric acid | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 3±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/17 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50= 9 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/12 | 15 | Linear | D | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 6±2 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/15 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 7±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/16 | 15 | Linear | L | Nal = 3-(1-naphthyl)alanine | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 6±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/9 | 15 | Linear | L | None | Methoxylation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 3±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/10 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 9±4 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/11 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 8±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/4 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 7±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/6 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 > 40 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/8 | 15 | Linear | L | None | Free | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 12±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/2 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | Not tested | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/3 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | Not tested | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 4±1 µM | 48-h | Cervix | None | ||
| 22100226 | 2012 | LL-III/1 | 15 | Linear | L | None | Amidation | Free | Antimicrobial and Antifungal | Lasioglossin III and its analogs | HeLa | Cervical Cancer | MTT/MTS assay | IC50 = 3±1 µM | 48-h | Cervix | None | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | HTB-9 | Bladder Cancer | MTT/MTS assay | ~30% cytotoxicity at 1 µM | 72-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | HTB-9 | Bladder Cancer | MTT/MTS assay | >40% cytotoxicity at 10 µM | 72-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | HTB-9 | Bladder Cancer | MTT/MTS assay | <20% cytotoxicity at 1 µM | 48-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | HTB-9 | Bladder Cancer | MTT/MTS assay | 20% cytotoxicity at 10 µM | 48-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | HTB-9 | Bladder Cancer | MTT/MTS assay | 40% cytotoxicity at 1 µM | 24-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | HTB-9 | Bladder Cancer | MTT/MTS assay | ~50% cytotoxicity at 10 µM | 24-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HTB-9 | Bladder Cancer | MTT/MTS assay | <5% cytotoxicity at 1 µM | 72-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HTB-9 | Bladder Cancer | MTT/MTS assay | <5% cytotoxicity at 10 µM | 72-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HTB-9 | Bladder Cancer | MTT/MTS assay | <5% cytotoxicity at 1 µM | 48-h | Bladder | WO2012042540A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HTB-9 | Bladder Cancer | MTT/MTS assay | <3% cytotoxicity at 10 µM | 48-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HTB-9 | Bladder Cancer | MTT/MTS assay | <15% cytotoxicity at 1 µM | 24-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HTB-9 | Bladder Cancer | MTT/MTS assay | ~15% cytotoxicity at 10 µM | 24-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HTB-9 | Bladder Cancer | MTT/MTS assay | <20% cytotoxicity at 1 µM | 72-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HTB-9 | Bladder Cancer | MTT/MTS assay | ~15% cytotoxicity at 10 µM | 72-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HTB-9 | Bladder Cancer | MTT/MTS assay | <5% cytotoxicity at 1 µM | 48-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HTB-9 | Bladder Cancer | MTT/MTS assay | <3% cytotoxicity at 10 µM | 48-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HTB-9 | Bladder Cancer | MTT/MTS assay | 20% cytotoxicity at 1 µM | 24-h | Bladder | WO2012042540A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HTB-9 | Bladder Cancer | MTT/MTS assay | ~10% cytotoxicity at 10 µM | 24-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | CaSki | Cervical Cancer | MTT/MTS assay | ~20% cytotoxicity at 1 µM | 72-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | CaSki | Cervical Cancer | MTT/MTS assay | ~45% cytotoxicity at 10 µM | 72-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | CaSki | Cervical Cancer | MTT/MTS assay | ~55% cytotoxicity at 10 µM | 48-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | CaSki | Cervical Cancer | MTT/MTS assay | ~40% cytotoxicity at 10 µM | 24-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | CaSki | Cervical Cancer | MTT/MTS assay | ~20% cytotoxicity at 1 µM | 48-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | CaSki | Cervical Cancer | MTT/MTS assay | >20% cytotoxicity at 10 µM | 72-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | CaSki | Cervical Cancer | MTT/MTS assay | ~20% cytotoxicity at 1 µM | 24-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | CaSki | Cervical Cancer | MTT/MTS assay | >20% cytotoxicity at 10 µM | 48-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | CaSki | Cervical Cancer | MTT/MTS assay | ~15% cytotoxicity at 1 µM | 72-h | Cervix | WO2012042540A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | CaSki | Cervical Cancer | MTT/MTS assay | ~15% cytotoxicity at 10 µM | 24-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | CaSki | Cervical Cancer | MTT/MTS assay | <3% cytotoxicity at 1 µM | 48-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | CaSki | Cervical Cancer | MTT/MTS assay | 20% cytotoxicity at 10 µM | 72-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | CaSki | Cervical Cancer | MTT/MTS assay | ~5% cytotoxicity at 1 µM | 24-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | CaSki | Cervical Cancer | MTT/MTS assay | <10% cytotoxicity at 10 µM | 48-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | CaSki | Cervical Cancer | MTT/MTS assay | <20% cytotoxicity at 1 µM | 72-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | CaSki | Cervical Cancer | MTT/MTS assay | ~5% cytotoxicity at 10 µM | 24-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | CaSki | Cervical Cancer | MTT/MTS assay | ~10% cytotoxicity at 1 µM | 48-h | Cervix | WO2012042540A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | SiHa | Cervical Cancer | MTT/MTS assay | ~45% cytotoxicity at 10 µM | 72-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | CaSki | Cervical Cancer | MTT/MTS assay | ~15% cytotoxicity at 1 µM | 24-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | SiHa | Cervical Cancer | MTT/MTS assay | ~20% cytotoxicity at 1 µM | 72-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | SiHa | Cervical Cancer | MTT/MTS assay | ~50% cytotoxicity at 10 µM | 48-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | SiHa | Cervical Cancer | MTT/MTS assay | <20% cytotoxicity at 1 µM | 48-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | SiHa | Cervical Cancer | MTT/MTS assay | >40% cytotoxicity at 10 µM | 24-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | SiHa | Cervical Cancer | MTT/MTS assay | >20% cytotoxicity at 1 µM | 24-h | Cervix | WO2012042540A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | SiHa | Cervical Cancer | MTT/MTS assay | ~40% cytotoxicity at 10 µM | 72-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | SiHa | Cervical Cancer | MTT/MTS assay | ~20% cytotoxicity at 1 µM | 72-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | SiHa | Cervical Cancer | MTT/MTS assay | >20% cytotoxicity at 10 µM | 48-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | SiHa | Cervical Cancer | MTT/MTS assay | <3% cytotoxicity at 1 µM | 48-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | SiHa | Cervical Cancer | MTT/MTS assay | >10% cytotoxicity at 10 µM | 24-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | SiHa | Cervical Cancer | MTT/MTS assay | 5% cytotoxicity at 1 µM | 24-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | SiHa | Cervical Cancer | MTT/MTS assay | 20% cytotoxicity at 10 µM | 72-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | SiHa | Cervical Cancer | MTT/MTS assay | <20% cytotoxicity at 1 µM | 72-h | Cervix | WO2012042540A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | SiHa | Cervical Cancer | MTT/MTS assay | <10% cytotoxicity at 10 µM | 48-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | SiHa | Cervical Cancer | MTT/MTS assay | 10% cytotoxicity at 1 µM | 48-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | SiHa | Cervical Cancer | MTT/MTS assay | 5% cytotoxicity at 10 µM | 24-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | SiHa | Cervical Cancer | MTT/MTS assay | ~15% cytotoxicity at 1 µM | 24-h | Cervix | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | HCT-116 | Colon Cancer | MTT/MTS assay | ~40% cytotoxicity at 10 µM | 72-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | HCT-116 | Colon Cancer | MTT/MTS assay | >30% cytotoxicity at 1 µM | 72-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | HCT-116 | Colon Cancer | MTT/MTS assay | >20% cytotoxicity at 10 µM | 48-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | HCT-116 | Colon Cancer | MTT/MTS assay | <20% cytotoxicity at 1 µM | 48-h | Colon | WO2012042540A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | HCT-116 | Colon Cancer | MTT/MTS assay | 50% cytotoxicity at 10 µM | 24-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | HCT-116 | Colon Cancer | MTT/MTS assay | >40% cytotoxicity at 1 µM | 24-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HCT-116 | Colon Cancer | MTT/MTS assay | <5% cytotoxicity at 10 µM | 72-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HCT-116 | Colon Cancer | MTT/MTS assay | <5% cytotoxicity at 1 µM | 72-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HCT-116 | Colon Cancer | MTT/MTS assay | <5% cytotoxicity at 10 µM | 48-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HCT-116 | Colon Cancer | MTT/MTS assay | ~5% cytotoxicity at 1 µM | 48-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HCT-116 | Colon Cancer | MTT/MTS assay | 15% cytotoxicity at 10 µM | 24-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HCT-116 | Colon Cancer | MTT/MTS assay | <15% cytotoxicity at 1 µM | 24-h | Colon | WO2012042540A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HCT-116 | Colon Cancer | MTT/MTS assay | 15% cytotoxicity at 10 µM | 72-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HCT-116 | Colon Cancer | MTT/MTS assay | <20% cytotoxicity at 1 µM | 72-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HCT-116 | Colon Cancer | MTT/MTS assay | 10% cytotoxicity at 10 µM | 24-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HCT-116 | Colon Cancer | MTT/MTS assay | <5% cytotoxicity at 1 µM | 48-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HCT-116 | Colon Cancer | MTT/MTS assay | <3% cytotoxicity at 10 µM | 48-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | UM-UC-3 | Bladder Cancer | MTT/MTS assay | >40% cytotoxicity at 1 µM | 72-h | Bladder | WO2012042540A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | UM-UC-3 | Bladder Cancer | MTT/MTS assay | ~50% cytotoxicity at 10 µM | 72-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | HCT-116 | Colon Cancer | MTT/MTS assay | 20% cytotoxicity at 1 µM | 24-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | UM-UC-3 | Bladder Cancer | MTT/MTS assay | ~50% cytotoxicity at 10 µM | 48-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | UM-UC-3 | Bladder Cancer | MTT/MTS assay | <30% cytotoxicity at 1 µM | 48-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | UM-UC-3 | Bladder Cancer | MTT/MTS assay | <30% cytotoxicity at 10 µM | 24-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | UM-UC-3 | Bladder Cancer | MTT/MTS assay | ~30% cytotoxicity at 1 µM | 24-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | UM-UC-3 | Bladder Cancer | MTT/MTS assay | <45% cytotoxicity at 10 µM | 72-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | UM-UC-3 | Bladder Cancer | MTT/MTS assay | ~45% cytotoxicity at 1 µM | 72-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | UM-UC-3 | Bladder Cancer | MTT/MTS assay | >25% cytotoxicity at 10 µM | 48-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | UM-UC-3 | Bladder Cancer | MTT/MTS assay | ~25% cytotoxicity at 1 µM | 48-h | Bladder | WO2012042540A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | UM-UC-3 | Bladder Cancer | MTT/MTS assay | ~25% cytotoxicity at 10 µM | 24-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | UM-UC-3 | Bladder Cancer | MTT/MTS assay | ~25% cytotoxicity at 1 µM | 24-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | UM-UC-3 | Bladder Cancer | MTT/MTS assay | <45% cytotoxicity at 10 µM | 72-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | UM-UC-3 | Bladder Cancer | MTT/MTS assay | ~45% cytotoxicity at 1 µM | 72-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | UM-UC-3 | Bladder Cancer | MTT/MTS assay | <25% cytotoxicity at 10 µM | 48-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | UM-UC-3 | Bladder Cancer | MTT/MTS assay | ~25% cytotoxicity at 1 µM | 48-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | UM-UC-3 | Bladder Cancer | MTT/MTS assay | <10% cytotoxicity at 10 µM | 24-h | Bladder | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | UM-UC-3 | Bladder Cancer | MTT/MTS assay | 10% cytotoxicity at 1 µM | 24-h | Bladder | WO2012042540A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | COLO-205 | Colon Cancer | MTT/MTS assay | ~20% cytotoxicity at 10 µM | 72-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | COLO-205 | Colon Cancer | MTT/MTS assay | <5% cytotoxicity at 1 µM | 72-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | COLO-205 | Colon Cancer | MTT/MTS assay | ~35% cytotoxicity at 10 µM | 48-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | COLO-205 | Colon Cancer | MTT/MTS assay | >20% cytotoxicity at 1 µM | 48-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | COLO-205 | Colon Cancer | MTT/MTS assay | <5% cytotoxicity at 10 µM | 24-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | MB30 | 30 | Linear | L | None | Free | Free | Anticancer | Derived from the MPT63 secreted protein | COLO-205 | Colon Cancer | MTT/MTS assay | <5% cytotoxicity at 1 µM | 24-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | COLO-205 | Colon Cancer | MTT/MTS assay | <5% cytotoxicity at 10 µM | 72-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | COLO-205 | Colon Cancer | MTT/MTS assay | >10% cytotoxicity at 1 µM | 72-h | Colon | WO2012042540A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | COLO-205 | Colon Cancer | MTT/MTS assay | >10% cytotoxicity at 10 µM | 48-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | COLO-205 | Colon Cancer | MTT/MTS assay | 10% cytotoxicity at 1 µM | 48-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | COLO-205 | Colon Cancer | MTT/MTS assay | ~10% cytotoxicity at 10 µM | 24-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG23 | 22 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | COLO-205 | Colon Cancer | MTT/MTS assay | <5% cytotoxicity at 1 µM | 24-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | COLO-205 | Colon Cancer | MTT/MTS assay | <5% cytotoxicity at 10 µM | 72-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | COLO-205 | Colon Cancer | MTT/MTS assay | <5% cytotoxicity at 1 µM | 72-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | COLO-205 | Colon Cancer | MTT/MTS assay | >20% cytotoxicity at 10 µM | 48-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | COLO-205 | Colon Cancer | MTT/MTS assay | <5% cytotoxicity at 1 µM | 24-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | COLO-205 | Colon Cancer | MTT/MTS assay | <20% cytotoxicity at 10 µM | 24-h | Colon | WO_2012042540_A2 | ||
| None | 2012 | TG20 | 20 | Linear | L | None | Free | Free | Anticancer | Derived from the SAG1 surface protein from the parasite Toxoplasma gondii | COLO-205 | Colon Cancer | MTT/MTS assay | ~15% cytotoxicity at 1 µM | 48-h | Colon | WO2012042540A2 | ||
| 23893605 | 2013 | Melittin | 26 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =2.1 ± 0.1 µM | 2-h | Skin | None | ||
| 23893605 | 2013 | Melittin | 26 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =1.8 ± 0.1 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | Melittin | 26 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =1.4 ± 0.1 µM | 24-h | Skin | None | ||
| 23533710 | 2013 | LfcinB | 12 | Linear | L | None | Amidation | Free | Antihypertensive and Antimicrobial and Antiviral and Antioxidant | Bovine milk | AZ-97 | Colon Cancer | MTT/MTS assay | Inhibition at 0.1g/l | NA | Colon | None | ||
| 23533710 | 2013 | β-Casomorphins 5 f(60_64) | 4 | Linear | L | None | Amidation | Free | Immunomodulant, Antihypertensive, Antimicrobial,Antiviral, and Antioxidant | Bovine milk | AZ-97 | Colon Cancer | MTT/MTS assay | Inhibition at 9-11g/l | NA | Colon | None | ||
| 23533710 | 2013 | αs1-casein f(90_95) | 6 | Linear | L | None | Amidation | Free | Immunomodulant, Antihypertensive, Antimicrobial,Antiviral, and Antioxidant | Bovine milk | AZ-97 | Colon Cancer | MTT/MTS assay | Inhibition at 12-15g/l | NA | Colon | None | ||
| 23533710 | 2013 | Caseinphosphopeptides | 5 | Linear | L | None | Amidation | Free | Immunomodulant, Antihypertensive, Antimicrobial,Antiviral, and Antioxidant | Bovine milk | AZ-97 | Colon Cancer | MTT/MTS assay | Inhibition at 24-28g/l | NA | Colon | None | ||
| 22820149 | 2012 | BAA-1 | Not Available | Linear | L | None | Amidation | Free | Antimicrobial | Bovine lactoferrin (Lf-B) | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50 = 8.1 µg/ml | 1-h | Blood | None | ||
| 22820149 | 2012 | BAA-2 | Not Available | Linear | L | None | Amidation | Free | Antimicrobial | Bovine lactoferrin (Lf-B) | Ramos | Lymphoma Cancer | MTT/MTS assay | IC50 = 3.8 µg/ml | 8-h | Blood | None | ||
| 23893605 | 2013 | C7A-Δ | 24 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =7.5 ± 0.4 µM | 30-Min | Skin | None | ||
| 23893605 | 2013 | C7A-Δ | 24 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =13.8 ± 2.0 µM | 2-h | Skin | None | ||
| 23893605 | 2013 | C7A-Δ | 24 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =9.3 ± 1.5 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | C7A-Δ | 24 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =13.1 ± 0.9 µM | 24-h | Skin | None | ||
| 23893605 | 2013 | NK11 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 >>100 µM | 30-Min | Skin | None | ||
| 23893605 | 2013 | NK11 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 >>100 µM | 2-h | Skin | None | ||
| 23893605 | 2013 | NK11 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 >>100 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | NK11 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 >>100 µM | 24-h | Skin | None | ||
| 23893605 | 2013 | Melittin | 26 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =3.2 ± 0.1 µM | 30-Min | Skin | None | ||
| 23893605 | 2013 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =12.3 ± 1.0 µM | 24-h | Skin | None | ||
| 23893605 | 2013 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =8.3 ± 0.5 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =12.3 ± 2.0 µM | 2-h | Skin | None | ||
| 23893605 | 2013 | C7A-D21K | 27 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =8.4 ± 0.2 µM | 30-Min | Skin | None | ||
| 23893605 | 2013 | C7A | 27 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =37 ± 4.3 µM | 24-h | Skin | None | ||
| 23893605 | 2013 | C7A | 27 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =12.1 ± 1.6 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | C7A | 27 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =13.0 ± 1.0 µM | 2-h | Skin | None | ||
| 23893605 | 2013 | C7A | 27 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 =10.6 ± 0.4 µM | 30-Min | Skin | None | ||
| 23893605 | 2013 | NK-2 | 27 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 = ~40 µM | 24-h | Skin | None | ||
| 23893605 | 2013 | NK-2 | 27 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 = ~50 µM | 4-h | Skin | None | ||
| 23893605 | 2013 | NK-2 | 27 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 = ~50 µM | 2-h | Skin | None | ||
| 23893605 | 2013 | NK-2 | 27 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | E42/02 | Skin Cancer | MTT/MTS assay | IC50 = ~70 µM | 30-Min | Skin | None | ||
| 21453492, 23533710 | 2011 | LfcinB | 12 | Linear | L | None | Free | Free | Antimicrobial and Anticancer | Bovine lactoferrin (Lf-B) | Kelly | Brain Tumor | MTT/MTS assay | IC50 =141 ± 3 µM | 30-Min | Brain | None | ||
| 21453492, 23533710 | 2011 | LfcinB | 12 | Linear | L | None | Free | Free | Antimicrobial and Anticancer | Bovine lactoferrin (Lf-B) | MT-1 | Breast Cancer | MTT/MTS assay | IC50 > 160 µM | 30-Min | Breast | None | ||
| 21453492 | 2011 | LTX-318 | 9 | Linear | L | Dip = diphenylalanine, O=ornithine | Amidation | Free | Antimicrobial | Synthetic peptide | Kelly | Brain Tumor | MTT/MTS assay | IC50 =78 ± 7 µM | 30-Min | Brain | None | ||
| 21453492, 23533710 | 2011 | LfcinB | 12 | Linear | L | None | Free | Free | Antimicrobial and Anticancer | Bovine lactoferrin (Lf-B) | HT-29 | Colon Cancer | MTT/MTS assay | IC50 > 160 µM | 30-Min | Colon | None | ||
| 21453492 | 2011 | LTX-318 | 9 | Linear | L | Dip = diphenylalanine, O=ornithine | Amidation | Free | Antimicrobial | Synthetic peptide | MT-1 | Breast Cancer | MTT/MTS assay | IC50 =216 ± 36 µM | 30-Min | Breast | None | ||
| 21453492 | 2011 | LTX-318 | 9 | Linear | L | Dip = diphenylalanine, O=ornithine | Amidation | Free | Antimicrobial | Synthetic peptide | HT-29 | Colon Cancer | MTT/MTS assay | IC50 =248 ± 5 µM | 30-Min | Colon | None | ||
| 21453492 | 2011 | LTX-315 | 9 | Linear | L | Dip = diphenylalanine | Amidation | Free | Antimicrobial | Synthetic peptide | MT-1 | Breast Cancer | MTT/MTS assay | IC50 =31 ± 3 µM | 30-Min | Breast | None | ||
| 21453492 | 2011 | LTX-315 | 9 | Linear | L | Dip = diphenylalanine | Amidation | Free | Antimicrobial | Synthetic peptide | Kelly | Brain Tumor | MTT/MTS assay | IC50 =14 ± 1 µM | 30-Min | Brain | None | ||
| 21453492 | 2011 | LTX-315 | 9 | Linear | L | Dip = diphenylalanine | Amidation | Free | Antimicrobial | Synthetic peptide | HT-29 | Colon Cancer | MTT/MTS assay | IC50 =38 ± 3 µM | 30-Min | Colon | None | ||
| 21453492 | 2011 | LTX-302 | 9 | Linear | L | Dip = diphenylalanine | Amidation | Free | Antimicrobial | Synthetic peptide | Kelly | Brain Tumor | MTT/MTS assay | IC50 =28 ± 0 µM | 30-Min | Brain | None | ||
| 21453492 | 2011 | LTX-302 | 9 | Linear | L | Dip = diphenylalanine | Amidation | Free | Antimicrobial | Synthetic peptide | MT-1 | Breast Cancer | MTT/MTS assay | IC50 =73 ± 2 µM | 30-Min | Breast | None | ||
| 21453492 | 2011 | LTX-302 | 9 | Linear | L | Dip = diphenylalanine | Amidation | Free | Antimicrobial | Synthetic peptide | HT-29 | Colon Cancer | MTT/MTS assay | IC50 =75 ± 5 µM | 30-Min | Colon | None | ||
| 22934601 | 2012 | PTP-7b | 13 | Linear | L | None | Free | Free | Anticancer | Synthetic peptide | A-549 | Lung Cancer | MTT/MTS assay | IC50 =32 µM | NA | Lung | None | ||
| 22934601 | 2012 | PTP-7a | 13 | Linear | L | None | Free | Free | Anticancer | Synthetic peptide | A-549 | Lung Cancer | MTT/MTS assay | IC50 =28 µM | NA | Lung | None | ||
| 22783018 | 2012 | N29D | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SNU-1 | Gastric Cancer | Cell Viability assay | <40% cell viability at 50 µM | NA | Stomach | None | ||
| 22783018 | 2012 | N29D | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SNU-1 | Gastric Cancer | Cell Viability assay | 100% cell viability at 5 µM | NA | Stomach | None | ||
| 22783018 | 2012 | N29D | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | U-937 | Lymphoma Cancer | Cell Viability assay | <60% cell viability at 50 µM | NA | Blood | None | ||
| 22783018 | 2012 | N29D | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | U-937 | Lymphoma Cancer | Cell Viability assay | 100% cell viability at 5 µM | NA | Blood | None | ||
| 22783018 | 2012 | N29D | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SW-480 | Colon Cancer | Cell Viability assay | 60% cell viability at 50 µM | NA | Colon | None | ||
| 22783018 | 2012 | N29D | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SW-480 | Colon Cancer | Cell Viability assay | >100% cell viability at 5 µM | NA | Colon | None | ||
| 22783018 | 2012 | N29N | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SNU-1 | Gastric Cancer | Cell Viability assay | <20% cell viability at 50 µM | NA | Stomach | None | ||
| 22783018 | 2012 | N29N | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SNU-1 | Gastric Cancer | Cell Viability assay | <100% cell viability at 5 µM | NA | Stomach | None | ||
| 22783018 | 2012 | N29N | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | U-937 | Lymphoma Cancer | Cell Viability assay | <40% cell viability at 50 µM | NA | Blood | None | ||
| 22783018 | 2012 | N29N | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | U-937 | Lymphoma Cancer | Cell Viability assay | 100% cell viability at 5 µM | NA | Blood | None | ||
| 22783018 | 2012 | N29N | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SW-480 | Colon Cancer | Cell Viability assay | 40% cell viability at 50 µM | NA | Colon | None | ||
| 22783018 | 2012 | N29N | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SW-480 | Colon Cancer | Cell Viability assay | 100% cell viability at 5 µM | NA | Colon | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50 =12.55 µM | 72-h | Ovary | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50 =22.25 µM | 72-h | Skin | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 =29.10 µM | 72-h | Prostate | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50 =22.51 µM | 72-h | Stomach | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | HCT-116 | Colon Cancer | MTT/MTS assay | IC50 =14.80 µM | 72-h | Colon | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | A-549 | Lung Cancer | MTT/MTS assay | IC50 =14.53 µM | 72-h | Lung | None | ||
| 22644847 | 2012 | GA-K4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | A-498 | Renal Cancer | MTT/MTS assay | IC50 =21.48 µM | 72-h | Renal | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50 | 72-h | Ovary | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50 =27.39 µM | 72-h | Skin | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 =47.69 µM | 72-h | Prostate | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | HCT-116 | Colon Cancer | MTT/MTS assay | IC50 =27.00 µM | 72-h | Colon | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50 =26.70 µM | 72-h | Stomach | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | A-498 | Renal Cancer | MTT/MTS assay | IC50 =41.21 µM | 72-h | Renal | None | ||
| 22644847 | 2012 | GA-K3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | A-549 | Lung Cancer | MTT/MTS assay | IC50 =25.20 µM | 72-h | Lung | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50 =13.16 µM | 72-h | Skin | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50 =14.58 µM | 72-h | Ovary | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | HCT-116 | Colon Cancer | MTT/MTS assay | IC50 =14.80 µM | 72-h | Colon | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50 =13.77 µM | 72-h | Stomach | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 =24.32 µM | 72-h | Prostate | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | A-498 | Renal Cancer | MTT/MTS assay | IC50 =22.59 µM | 72-h | Renal | None | ||
| 22644847 | 2012 | GA-W4 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | A-549 | Lung Cancer | MTT/MTS assay | IC50 =15.88 µM | 72-h | Lung | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50 =22.06 µM | 72-h | Ovary | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 =46.51 µM | 72-h | Prostate | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50 =13.97 µM | 72-h | Skin | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50 =24.31 µM | 72-h | Stomach | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | HCT-116 | Colon Cancer | MTT/MTS assay | IC50 =24.63 µM | 72-h | Colon | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | A-549 | Lung Cancer | MTT/MTS assay | IC50 =20.36 µM | 72-h | Lung | None | ||
| 22644847 | 2012 | GA-W3 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Undecapeptide analogues derived from Brevinin-1EMa | A-498 | Renal Cancer | MTT/MTS assay | IC50 =22.88 µM | 72-h | Renal | None | ||
| 22413859 | 2012 | SVS-2 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | MDA-MB-436 | Breast Cancer | MTT/MTS assay | IC50 >100 µM | 24-h | Breast | None | ||
| 22413859 | 2012 | SVS-2 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | MCF-7 | Breast Cancer | MTT/MTS assay | IC50 >100 µM | 24-h | Breast | None | ||
| 22413859 | 2012 | SVS-2 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | KB | Oral Cancer | MTT/MTS assay | IC50 >100 µM | 24-h | Oral mucosa | None | ||
| 22413859 | 2012 | SVS-2 | 18 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic peptide | A-549 | Lung Cancer | MTT/MTS assay | IC50 >100 µM | 24-h | Lung | None | ||
| 22413859 | 2012 | D-SVS-1 | 18 | Linear | Mix | None | Amidation | Free | Antimicrobial | Synthetic peptide | MDA-MB-436 | Breast Cancer | MTT/MTS assay | IC50 =3.2±0.4 µM | 24-h | Breast | None | ||
| 22413859 | 2012 | D-SVS-1 | 18 | Linear | Mix | None | Amidation | Free | Antimicrobial | Synthetic peptide | MCF-7 | Breast Cancer | MTT/MTS assay | IC50 =4.7±0.4 µM | 24-h | Breast | None | ||
| 22413859 | 2012 | D-SVS-1 | 18 | Linear | Mix | None | Amidation | Free | Antimicrobial | Synthetic peptide | KB | Oral Cancer | MTT/MTS assay | IC50 =4.5±0.5 µM | 24-h | Oral mucosa | None | ||
| 22413859 | 2012 | D-SVS-1 | 18 | Linear | Mix | None | Amidation | Free | Antimicrobial | Synthetic peptide | A-549 | Lung Cancer | MTT/MTS assay | IC50 =3.2±0.6 µM | 24-h | Lung | None | ||
| 22413859 | 2012 | SVS-1 | 18 | Linear | Mix | None | Amidation | Free | Antimicrobial | Synthetic peptide | MDA-MB-436 | Breast Cancer | MTT/MTS assay | IC50 =5.6±0.5 µM | 24-h | Breast | None | ||
| 22413859 | 2012 | SVS-1 | 18 | Linear | Mix | None | Amidation | Free | Antimicrobial | Synthetic peptide | MCF-7 | Breast Cancer | MTT/MTS assay | IC50 =8.1±0.8 µM | 24-h | Breast | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | MDBK | Renal Cancer | MTT/MTS assay | NA | 48-h | Renal | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | MDBK | Renal Cancer | MTT/MTS assay | NA | 48-h | Renal | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | MDBK | Renal Cancer | MTT/MTS assay | NA | 48-h | Renal | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | MDBK | Renal Cancer | MTT/MTS assay | NA | 48-h | Renal | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | MDBK | Renal Cancer | MTT/MTS assay | NA | 48-h | Renal | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | Vero | Renal Cancer | MTT/MTS assay | NA | 48-h | Renal | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | CEF | Tumor | MTT/MTS assay | NA | 48-h | Not Available | None | ||
| 22413859 | 2012 | SVS-1 | 18 | Linear | Mix | None | Amidation | Free | Antimicrobial | Bovine lactoferrin (Lf-B) | KB | Oral Cancer | MTT/MTS assay | NA | 24-h | Oral mucosa | None | ||
| 22413859 | 2012 | SVS-1 | 18 | Linear | Mix | None | Amidation | Free | Antimicrobial | Synthetic peptide | A-549 | Lung Cancer | MTT/MTS assay | NA | 24-h | Lung | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | MDBK | Renal Cancer | MTT/MTS assay | NA | 48-h | Renal | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | MDBK | Renal Cancer | MTT/MTS assay | NA | 48-h | Renal | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | MDBK | Renal Cancer | MTT/MTS assay | NA | 48-h | Renal | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | MDBK | Renal Cancer | MTT/MTS assay | NA | 48-h | Renal | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | MDBK | Renal Cancer | MTT/MTS assay | NA | 48-h | Renal | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | CEF | Tumor | MTT/MTS assay | NA | 48-h | Not Available | None | ||
| 22184121 | 2011 | BPP-II | 5 | Linear | L | None | Free | Free | Antitumor | Immunomodulatory bursal-derived Pentapeptide-II | Vero | Renal Cancer | MTT/MTS assay | NA | 48-h | Renal | None | ||
| 23301519 | 2013 | linear (RW)4-Dox | 8 | Linear | L | Doxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ] | Free | Free | Anticancer | Doxorubicin (Dox) is a well-known anthracycline which has been conjugated to a CPP | MDA-MB-468 | Breast Cancer | MTT/MTS assay | 60-74% antiproliferative activity at 1 µM | 72 to 120-h | Breast | None | ||
| 23301519 | 2013 | linear (RW)4-Dox | 8 | Linear | L | Doxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ] | Free | Free | Anticancer | Doxorubicin (Dox) is a well-known anthracycline which has been conjugated to a CPP | HCT-116 | Colon Cancer | MTT/MTS assay | 21-61% antiproliferative activity at 1 µM | 72 to 120-h | Colon | None | ||
| 23301519 | 2013 | linear (RW)4-Dox | 8 | Linear | L | Doxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ] | Free | Free | Anticancer | Doxorubicin (Dox) is a well-known anthracycline which has been conjugated to a CPP | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | 46-69% antiproliferative activity at 1 µM | 72 to 120-h | Blood | None | ||
| 23301519 | 2013 | linear (RW)4-Dox | 8 | Linear | L | Doxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ] | Free | Free | Anticancer | Doxorubicin (Dox) is a well-known anthracycline which has been conjugated to a CPP | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | 28-34% antiproliferative activity at 1 µM | 72 to 120-h | Ovary | None | ||
| 23301519 | 2013 | Cyclic [W(RW)4 ]-Dox | 9 | Cyclic | L | Doxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ] | Free | Free | Anticancer | Doxorubicin (Dox) is a well-known anthracycline which has been conjugated to a CPP | MDA-MB-468 | Breast Cancer | MTT/MTS assay | 60-79% inhibition of cell proliferation at 1 µM | 72 to 120-h | Breast | None | ||
| 23627474 | 2013 | PTPRJ-pep19.7 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 20 ± 1.4% cell growth inhibition at 160 µM in 72 hours | 72-h | Cervix | None | ||
| 23301519 | 2013 | Cyclic [W(RW)4 ]-Dox | 9 | Cyclic | L | Doxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ] | Free | Free | Anticancer | Doxorubicin (Dox) is a well-known anthracycline which has been conjugated to a CPP | CCRF-CEM | Leukemia Cancer | MTT/MTS assay | 62-73% inhibition of cell proliferation at 1 µM | 72 to 120-h | Blood | None | ||
| 23301519 | 2013 | Cyclic [W(RW)4 ]-Dox | 9 | Cyclic | L | Doxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ] | Free | Free | Anticancer | Doxorubicin (Dox) is a well-known anthracycline which has been conjugated to a CPP | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | 51-74% inhibition of cell proliferation at 1 µM | 72 to 120-h | Ovary | None | ||
| 23301519 | 2013 | Cyclic [W(RW)4 ]-Dox | 9 | Cyclic | L | Doxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ] | Free | Free | Anticancer | Doxorubicin (Dox) is a well-known anthracycline which has been conjugated to a CPP | HCT-116 | Colon Cancer | MTT/MTS assay | 50-67% inhibition of cell proliferation at 1 µM | 72 to 120-h | Colon | None | ||
| 23627474 | 2013 | PTPRJ-pep19.5 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 2 ± 1.5% cell growth inhibition at 160 µM in 48 hours | 48-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.5 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 19 ± 4.2% cell growth inhibition at 160 µM in 72 hours | 72-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.6 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 19 ± 4.2% cell growth inhibition at 160 µM in 72 hours | 72-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.7 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 4.5 ± 2.13% cell growth inhibition at 160 µM in 48 hours | 48-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.3 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 51 ± 1.4% cell growth inhibition at 160 µM in 72 hours | 72-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.4 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 48.0 ± 2.82% cell growth inhibition at 160 µM in 24 hours | 24-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.4 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 62.5 ± 4.9% cell growth inhibition at 160 µM in 48 hours | 48-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.4 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 66.5 ± 2.12% cell growth inhibition at 160 µM in 72 hours | 72-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.2 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 30 ± 2.82% cell growth inhibition at 160 µM in 48 hours | 48-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.2 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 32.0 ± 4.2% cell growth inhibition at 160 µM in 72 hours | 72-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.3 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 28 ± 5.5% cell growth inhibition at 160 µM in 24 hours | 24-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.3 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 46 ± 4.2% cell growth inhibition at 160 µM in 48 hours | 48-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 4.5 ± 0.1.4% cell growth inhibition at 160 µM in 48 hours | 48-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 19 ± 2.82% cell growth inhibition at 160 µM in 72 hours | 72-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.0 | 9 | Linear | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 4 ± 1.4% cell growth inhibition at 160 µM in 72 hours | 72-h | Cervix | None | ||
| 23627474 | 2013 | PTPRJ-pep19.2 | 9 | Cyclic(C1-C9) | L | None | Free | Free | Anticancer | PTPRJ agonist peptides | HeLa | Cervical Cancer | Trypan blue assay | 16.5 ± 2.12% cell growth inhibition at 160 µM in 24 hours | 24-h | Cervix | None | ||
| 23770440 | 2013 | TsAP-S2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Derivative of TsAP-1, Brazilian yellow scorpion venom peptide | MCF-7 | Breast Cancer | MTT/MTS assay | IC50 = 1.8 µM | 24-h | Breast | None | ||
| 23770440 | 2013 | TsAP-S2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Derivative of TsAP-1, Brazilian yellow scorpion venom peptide | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 = 1.6 µM | 24-h | Prostate | None | ||
| 23770440 | 2013 | TsAP-S2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Derivative of TsAP-1, Brazilian yellow scorpion venom peptide | U251-MG | Brain Tumor | MTT/MTS assay | IC50 = 2.0 µM | 24-h | Brain | None | ||
| 23770440 | 2013 | TsAP-S2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Derivative of TsAP-1, Brazilian yellow scorpion venom peptide | HI-57 | Lung Cancer | MTT/MTS assay | IC50 = 0.83 µM | 24-h | Lung | None | ||
| 23770440 | 2013 | TsAP-S2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Derivative of TsAP-1, Brazilian yellow scorpion venom peptide | H-838 | Lung Cancer | MTT/MTS assay | IC50 = 1.6 µM | 24-h | Lung | None | ||
| 23770440 | 2013 | TsAP-S1 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Derivative of TsAP-1, Brazilian yellow scorpion venom peptide | MCF-7 | Breast Cancer | MTT/MTS assay | IC50 = 1.8 µM | 24-h | Breast | None | ||
| 23770440 | 2013 | TsAP-S1 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Derivative of TsAP-1, Brazilian yellow scorpion venom peptide | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 = 2.1 µM | 24-h | Prostate | None | ||
| 23770440 | 2013 | TsAP-S1 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Derivative of TsAP-1, Brazilian yellow scorpion venom peptide | U251-MG | Brain Tumor | MTT/MTS assay | IC50 = 2.9 µM | 24-h | Brain | None | ||
| 23770440 | 2013 | TsAP-2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Venom-derived cDNot Available library of the Brazilian yellow scorpion, Tityus serrulatus | U251-MG | Brain Tumor | MTT/MTS assay | IC50 = 15.4 µM | 24-h | Brain | None | ||
| 23770440 | 2013 | TsAP-S1 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Derivative of TsAP-1, Brazilian yellow scorpion venom peptide | HI-57 | Lung Cancer | MTT/MTS assay | IC50 = 1.5 µM | 24-h | Lung | None | ||
| 23770440 | 2013 | TsAP-S1 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Derivative of TsAP-1, Brazilian yellow scorpion venom peptide | H-838 | Lung Cancer | MTT/MTS assay | IC50 = 1.6 µM | 24-h | Lung | None | ||
| 23770440 | 2013 | TsAP-2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Venom-derived cDNot Available library of the Brazilian yellow scorpion, Tityus serrulatus | H-838 | Lung Cancer | MTT/MTS assay | IC50 = 11.0 µM | 24-h | Lung | None | ||
| 23770440 | 2013 | TsAP-2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Venom-derived cDNot Available library of the Brazilian yellow scorpion, Tityus serrulatus | MCF-7 | Breast Cancer | MTT/MTS assay | IC50 = 6.4 µM | 24-h | Breast | None | ||
| 23770440 | 2013 | TsAP-2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Venom-derived cDNot Available library of the Brazilian yellow scorpion, Tityus serrulatus | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 = 13.3 µM | 24-h | Prostate | None | ||
| 23770440 | 2013 | TsAP-1 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Venom-derived cDNot Available library of the Brazilian yellow scorpion, Tityus serrulatus | HI-57 | Lung Cancer | MTT/MTS assay | IC50 =55.9 µM | 24-h | Lung | None | ||
| 23770440 | 2013 | TsAP-1 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Venom-derived cDNot Available library of the Brazilian yellow scorpion, Tityus serrulatus | H-838 | Lung Cancer | MTT/MTS assay | IC50 =52.5 µM | 24-h | Lung | None | ||
| 23770440 | 2013 | TsAP-2 | 17 | Linear | L | None | Amidation | Free | Antimicrobial | Venom-derived cDNot Available library of the Brazilian yellow scorpion, Tityus serrulatus | HI-57 | Lung Cancer | MTT/MTS assay | IC50 = 4.1 µM | 24-h | Lung | None | ||
| 23993331 | 2013 | MAP-04-04 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Analogs of Ixosin-B amide | MCF-7 | Breast Cancer | MTT/MTS assay | Cell viability >80% at 75 µM | 48-h | Breast | None | ||
| 23993331 | 2013 | MAP-04-04 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Analogs of Ixosin-B amide | MCF-7 | Breast Cancer | MTT/MTS assay | Cell viability >80% at 100 µM | 48-h | Breast | None | ||
| 23993331 | 2013 | MAP-04-03 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Analogs of Ixosin-B amide | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=61.5 µM | 48-h | Breast | None | ||
| 23993331 | 2013 | MAP-04-03 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Analogs of Ixosin-B amide | MCF-7 | Breast Cancer | MTT/MTS assay | Cell viability <40% at 75 µM | 48-h | Breast | None | ||
| 23993331 | 2013 | MAP-04-03 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Analogs of Ixosin-B amide | MCF-7 | Breast Cancer | MTT/MTS assay | Cell viability >20% at 100 µM | 48-h | Breast | None | ||
| 23993331 | 2013 | MAP-04-03 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Analogs of Ixosin-B amide | MCF-7 | Breast Cancer | MTT/MTS assay | Cell viability ~100% at 25 µM | 48-h | Breast | None | ||
| 23993331 | 2013 | MAP-04-04 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Analogs of Ixosin-B amide | MCF-7 | Breast Cancer | MTT/MTS assay | Cell viability >80% at 50 µM | 48-h | Breast | None | ||
| 23993331 | 2013 | MAP-04-03 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Analogs of Ixosin-B amide | MCF-7 | Breast Cancer | MTT/MTS assay | Cell viability >80% at 25 µM | 48-h | Breast | None | ||
| 23993331 | 2013 | MAP-04-03 | 11 | Linear | L | None | Amidation | Free | Antimicrobial | Analogs of Ixosin-B amide | MCF-7 | Breast Cancer | MTT/MTS assay | Cell viability ~50% at 50 µM | 48-h | Breast | None | ||
| 22783018 | 2012 | N29D | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SNU-1 | Gastric Cancer | Cell Viability assay | <100% cell viability at 5 µM | 24-h | Stomach | None | ||
| 22783018 | 2012 | N29D | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SNU-1 | Gastric Cancer | Cell Viability assay | <40% cell viability at 50 µM | 24-h | Stomach | None | ||
| 22783018 | 2012 | N29D | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SW-480 | Colon Cancer | Cell Viability assay | 60% cell viability at 50 µM | 24-h | Colon | None | ||
| 22783018 | 2012 | N29D | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | U-937 | Lymphoma Cancer | Cell Viability assay | 100% cell viability at 5 µM | 24-h | Blood | None | ||
| 22783018 | 2012 | N29D | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | U-937 | Lymphoma Cancer | Cell Viability assay | <60% cell viability at 50 µM | 24-h | Blood | None | ||
| 22783018 | 2012 | N29D | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SW-480 | Colon Cancer | Cell Viability assay | >100% cell viability at 5 µM | 24-h | Colon | None | ||
| 22783018 | 2012 | N29N | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SNU-1 | Gastric Cancer | Cell Viability assay | <20% cell viability at 50 µM | 24-h | Stomach | None | ||
| 22783018 | 2012 | N29N | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SNU-1 | Gastric Cancer | Cell Viability assay | <100% cell viability at 5 µM | 24-h | Stomach | None | ||
| 22783018 | 2012 | N29N | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | U-937 | Lymphoma Cancer | Cell Viability assay | <40% cell viability at 50 µM | 24-h | Blood | None | ||
| 22783018 | 2012 | N29N | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | U-937 | Lymphoma Cancer | Cell Viability assay | 100% cell viability at 5 µM | 24-h | Blood | None | ||
| 22783018 | 2012 | N29N | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SW-480 | Colon Cancer | Cell Viability assay | 40% cell viability at 50 µM | 24-h | Colon | None | ||
| 22783018 | 2012 | N29N | 30 | Linear | L | None | Free | Free | Antibacterial and Anticancer | Synthetic peptide | SW-480 | Colon Cancer | Cell Viability assay | 100% cell viability at 5 µM | 24-h | Colon | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 10 % Cytotoxicity at 3.125 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 1 % Cytotoxicity at 6.25 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 20 % Cytotoxicity at 12.5 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 25 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 50 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 15 % Cytotoxicity at 3.125 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 35 % Cytotoxicity at 6.25 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 30 % Cytotoxicity at 12.5 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 85 % Cytotoxicity at 25 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 50 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 35 % Cytotoxicity at 3.125 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 30 % Cytotoxicity at 6.25 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 48 % Cytotoxicity at 12.5 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 84% Cytotoxicity at 25 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 84 % Cytotoxicity at 50 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 25 % Cytotoxicity at 3.125 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 30 % Cytotoxicity at 6.25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 45 % Cytotoxicity at 12.5 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 85 % Cytotoxicity at 25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 80 % Cytotoxicity at 50 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 18 % Cytotoxicity at 3.125 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 18 % Cytotoxicity at 6.25 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 18 % Cytotoxicity at 12.5 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 82 % Cytotoxicity at 25 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 90 % Cytotoxicity at 50 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 10 % Cytotoxicity at 3.125 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 4 % Cytotoxicity at 6.25 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 18 % Cytotoxicity at 12.5 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 70 % Cytotoxicity at 25 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 82 % Cytotoxicity at 50 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 5 % Cytotoxicity at 3.125 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 10 % Cytotoxicity at 6.25 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 10 % Cytotoxicity at 12.5 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 70 % Cytotoxicity at 25 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 78 % Cytotoxicity at 50 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 1 % Cytotoxicity at 3.125 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 5 % Cytotoxicity at 6.25 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 4 % Cytotoxicity at 12.5 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 60 % Cytotoxicity at 25 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-6 | 27 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 70 % Cytotoxicity at 50 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 10 % Cytotoxicity at 3.125 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 5 % Cytotoxicity at 6.25 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 25 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 15 % Cytotoxicity at 12.5 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 50 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 38 % Cytotoxicity at 3.125 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 39 % Cytotoxicity at 12.5 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 28 % Cytotoxicity at 6.25 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 95 % Cytotoxicity at 25 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 30 % Cytotoxicity at 3.125 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 97 % Cytotoxicity at 50 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 30 % Cytotoxicity at 6.25 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 30 % Cytotoxicity at 12.5 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 25 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 50 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 35 % Cytotoxicity at 3.125 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 35 % Cytotoxicity at 6.25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 40 % Cytotoxicity at 12.5 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 82 % Cytotoxicity at 25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 88 % Cytotoxicity at 50 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 5 % Cytotoxicity at 3.125 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 12 % Cytotoxicity at 6.25 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 15 % Cytotoxicity at 12.5 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 80 % Cytotoxicity at 25 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 90 % Cytotoxicity at 50 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 10 % Cytotoxicity at 3.125 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 5 % Cytotoxicity at 6.25 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 4 % Cytotoxicity at 12.5 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 68 % Cytotoxicity at 25 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 78 % Cytotoxicity at 50 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 4 % Cytotoxicity at 3.125 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 70 % Cytotoxicity at 25 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 75 % Cytotoxicity at 50 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 4 % Cytotoxicity at 12.5 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 44 % Cytotoxicity at 25 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 62 % Cytotoxicity at 50 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 3 % Cytotoxicity at 6.25 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 3 % Cytotoxicity at 3.125 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 8 % Cytotoxicity at 12.5 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 75 % Cytotoxicity at 25 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 4 % Cytotoxicity at 3.125 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 50 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 4 % Cytotoxicity at 6.25 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 12 % Cytotoxicity at 12.5 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 76 % Cytotoxicity at 50 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 70 % Cytotoxicity at 25 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 10 % Cytotoxicity at 3.125 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 5 %Cytotoxicity at 12.5 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 7 % Cytotoxicity at 6.25 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 70 % Cytotoxicity at 25 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 5 % Cytotoxicity at 3.125 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 75 % Cytotoxicity at 50 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 10 % Cytotoxicity at 6.25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 8 % Cytotoxicity at 12.5 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 60 % Cytotoxicity at 50 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 50 % Cytotoxicity at 25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 8 % Cytotoxicity at 12.5 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 3 % Cytotoxicity at 6.25 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 3 % Cytotoxicity at 3.125 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 75 % Cytotoxicity at 25 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 4 % Cytotoxicity at 3.125 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 90 % Cytotoxicity at 50 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 4 % Cytotoxicity at 6.25 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 70 % Cytotoxicity at 25 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 12 % Cytotoxicity at 12.5 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 10 % Cytotoxicity at 3.125 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 76 % Cytotoxicity at 50 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 5 % Cytotoxicity at 12.5 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 7 % Cytotoxicity at 6.25 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 70 % Cytotoxicity at 25 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 75 % Cytotoxicity at 50 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 10 % Cytotoxicity at 6.25 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 5 % Cytotoxicity at 3.125 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 8 % Cytotoxicity at 12.5 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 50 % Cytotoxicity at 25 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-8 | 16 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 60 % Cytotoxicity at 50 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 28 % Cytotoxicity at 3.125 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 30 % Cytotoxicity at 6.25 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 85 % Cytotoxicity at 25 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 38 % Cytotoxicity at 12.5 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 84 % Cytotoxicity at 50 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 28 % Cytotoxicity at 3.125 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 30 % Cytotoxicity at 6.25 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 46 % Cytotoxicity at 12.5 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 96 % Cytotoxicity at 25 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 95 % Cytotoxicity at 50 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 25 % Cytotoxicity at 3.125 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 25 % Cytotoxicity at 6.25 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 45 % Cytotoxicity at 12.5 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 95 % Cytotoxicity at 25 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 50 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 41 % Cytotoxicity at 6.25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 41 % Cytotoxicity at 6.25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 41 % Cytotoxicity at 6.25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 39 % Cytotoxicity at 3.125 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 41 % Cytotoxicity at 6.25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 42 % Cytotoxicity at 12.5 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 85 % Cytotoxicity at 25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 82 % Cytotoxicity at 50 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 77 % Cytotoxicity at 25 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 83% Cytotoxicity at 50 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 65% Cytotoxicity at 25 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 75 % Cytotoxicity at 50 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 65% Cytotoxicity at 25 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 75% Cytotoxicity at 50 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 38% Cytotoxicity at 25 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Epinecidin-1 | 21 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 45% Cytotoxicity at 50 mg/L | 3-h | Cervix | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | COLO-587 | Human epithelial Cancer | WST-1 assay | IC50=6.4 µM | 72-h | Pancreatic | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | LNCaP | Prostate Cancer | WST-1 assay | IC50= 6.2 µM | 72-h | Prostate | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | HuCCT-1 | Human epithelial Cancer | WST-1 assay | IC50= 8.3 µM | 72-h | Bileduct | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | U-251 | Brain Tumor | WST-1 assay | IC50=7.0 µM | 72-h | Brain | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | SN-19 | Brain Tumor | WST-1 assay | IC50= 7.8 µM | 72-h | Brain | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | SF-295 | Brain Tumor | WST-1 assay | IC50= 6.3 µM | 72-h | Brain | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | ZR75-1 | Breast Cancer | WST-1 assay | IC50= 9.3 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | BT-20 | Breast Cancer | WST-1 assay | IC50= 4.8 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | MDA-MB-231 | Breast Cancer | WST-1 assay | IC50= 7.8 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | SK-BR-3 | Breast Cancer | WST-1 assay | IC50= 6.5 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | T-47D | Breast Cancer | WST-1 assay | IC50= 4.0 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | BT-474 | Breast Cancer | WST-1 assay | IC50= 8.8 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | LNCaP | Prostate Cancer | WST-1 assay | IC50= 15.8 µM | 72-h | Prostate | None | ||
| 21849092 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | COLO-587 | Human epithelial Cancer | WST-1 assay | IC50= 13.5 µM | 72-h | Pancreatic | None | ||
| 21849092 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | HuCCT-1 | Human epithelial Cancer | WST-1 assay | IC50= 17.1 µM | 72-h | Bileduct | None | ||
| 21849092 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | U-251 | Brain Tumor | WST-1 assay | IC50= 17.0 µM | 72-h | Brain | None | ||
| 21849092 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | SF-295 | Brain Tumor | WST-1 assay | IC50= 19.1 µM | 72-h | Brain | None | ||
| 21849092 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | SN-19 | Brain Tumor | WST-1 assay | IC50= 21.9 µM | 72-h | Brain | None | ||
| 21849092 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | ZR75-1 | Breast Cancer | WST-1 assay | IC50= 19.4 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | BT-20 | Breast Cancer | WST-1 assay | IC50= 20.0 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | MDA-MB-231 | Breast Cancer | WST-1 assay | IC50= 27.0 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | SK-BR-3 | Breast Cancer | WST-1 assay | IC50= 25.7 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | T-47D | Breast Cancer | WST-1 assay | IC50= 14.1 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | BT-474 | Breast Cancer | WST-1 assay | IC50= 34.5 µM | 72-h | Breast | None | ||
| 23583573 | 2013 | Tempoprin-1CEa | 15 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese brown frog Rana chensinensis. | Bcap-37 | Breast Cancer | MTT/MTS assay | 30 % Cell viability at 40 µM | 1-h | Breast | None | ||
| 23583573 | 2013 | Tempoprin-1CEa | 15 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese brown frog Rana chensinensis. | Bcap-37 | Breast Cancer | MTT/MTS assay | 45% Cell viability at 30 µM | 1-h | Breast | None | ||
| 23583573 | 2013 | caspase 3 inhibitor | 4 | Linear | L | None | Fluoromethyl ketone(fmk) | Free | Anticancer | caspase 3 inhibitor | Bcap-37 | Breast Cancer | MTT/MTS assay | 35 % Cell viability at 40 µM | 1-h | Breast | None | ||
| 23583573 | 2013 | Tempoprin-1CEa | 15 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese brown frog Rana chensinensis. | Bcap-37 | Breast Cancer | MTT/MTS assay | 70% Cell viability at 20 µM | 1-h | Breast | None | ||
| 23583573 | 2013 | caspase 3 inhibitor | 4 | Linear | L | None | Fluoromethyl ketone(fmk) | Free | Anticancer | caspase 3 inhibitor | Bcap-37 | Breast Cancer | MTT/MTS assay | 65% Cell viability at 20 µM | 1-h | Breast | None | ||
| 23583573 | 2013 | caspase 3 inhibitor | 4 | Linear | L | None | Fluoromethyl ketone(fmk) | Free | Anticancer | caspase 3 inhibitor | Bcap-37 | Breast Cancer | MTT/MTS assay | 40% Cell viability at 30 µM | 1-h | Breast | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | MDA-MB-231 | Breast Cancer | WST-1 assay | IC50=5.7 µMol/L | 24-h | Breast | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | H-322 | Lung Cancer | WST-1 assay | IC50=3.6 µMol/L | 24-h | Lung | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | A-172 | Brain Tumor | WST-1 assay | IC50=6.8 µMol/L | 24-h | Brain | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | T98G | Brain Tumor | WST-1 assay | IC50=18.5 µMol/L | 24-h | Brain | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Bovine lactoferrin (Lf-B) | KB | Oral Cancer | WST-1 assay | IC50=13.2 µMol/L | 24-h | Oral mucosa | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | SU.86.86 | Pancreatic Cancer | WST-1 assay | IC50=7.5 µMol/L | 24-h | Pancreatic | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | BXPC-3 | Pancreatic Cancer | WST-1 assay | IC50=6.8 µMol/L | 24-h | Pancreatic | None | ||
| 22084165 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | MDA-MB-231 | Breast Cancer | WST-1 assay | IC50=18.5 µMol/L | 24-h | Breast | None | ||
| 22084165 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | H-322 | Lung Cancer | WST-1 assay | IC50=27.1 µMol/L | 24-h | Lung | None | ||
| 22084165 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | A-172 | Brain Tumor | WST-1 assay | IC50=30.5 µMol/L | 24-h | Brain | None | ||
| 22084165 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | T98G | Brain Tumor | WST-1 assay | IC50=77.3 µMol/L | 24-h | Brain | None | ||
| 22084165 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Bovine lactoferrin (Lf-B) | KB | Oral Cancer | WST-1 assay | IC50=37.4 µMol/L | 24-h | Oral mucosa | None | ||
| 22084165 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | SU.86.86 | Pancreatic Cancer | WST-1 assay | IC50=28.0 µMol/L | 24-h | Pancreatic | None | ||
| 22084165 | 2011 | Lytik | 17 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | BXPC-3 | Pancreatic Cancer | WST-1 assay | IC50=37.1 µMol/L | 24-h | Pancreatic | None | ||
| 23577112, 21871946 | 2012 | Tempoprin-1CEa | 15 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese brown frog Rana chensinensis. | MCF-7 | Breast Cancer | LDH leakage assay | 32% Cytotoxicity at 40 µM | 1-h | Breast | None | ||
| 23577112, 21871946 | 2012 | Tempoprin-1CEa | 15 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese brown frog Rana chensinensis. | MCF-7 | Breast Cancer | MTT/MTS assay | 61% Cell viability at 40 µM | 1-h | Breast | None | ||
| 23577112, 21871946 | 2012 | Tempoprin-1CEa | 15 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese brown frog Rana chensinensis. | MDA-MB-231 | Breast Cancer | MTT/MTS assay | 22% Cell viability at 40 µM | 1-h | Breast | None | ||
| 23577112, 21871946 | 2012 | Tempoprin-1CEa | 15 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese brown frog Rana chensinensis. | MDA-MB-231 | Breast Cancer | LDH leakage assay | 61% Cytotoxicity at 40 µM | 1-h | Breast | None | ||
| 23028527 | 2012 | Adenoregulin | 33 | Linear | L | None | Free | Free | Antimicrobial | South American frog Phyllomedusa bicolor | Raji | Lymphoma Cancer | LDH leakage assay | GI50 =2.57±0.75 µM | 24-h | Blood | None | ||
| 23028527 | 2012 | Adenoregulin | 33 | Linear | L | None | Free | Free | Antimicrobial | South American frog Phyllomedusa bicolor | MDA-MB-231 | Breast Cancer | LDH leakage assay | GI50 =8.06±0.50 µM | 24-h | Breast | None | ||
| 23028527 | 2012 | Adenoregulin | 33 | Linear | L | None | Free | Free | Antimicrobial | South American frog Phyllomedusa bicolor | DU-145 | Liver Cancer | LDH leakage assay | GI50 =0.91±0.04 µM | 24-h | Prostate | None | ||
| 23028527 | 2012 | Adenoregulin | 33 | Linear | L | None | Free | Free | Antimicrobial | South American frog Phyllomedusa bicolor | LNCaP | Prostate Cancer | LDH leakage assay | GI50 =0.31±0.15 µM | 24-h | Prostate | None | ||
| 23028527 | 2012 | Adenoregulin | 33 | Linear | L | None | Free | Free | Antimicrobial | South American frog Phyllomedusa bicolor | PC-3 | Prostate Cancer | LDH leakage assay | GI50 =1.24±0.23 µM | 24-h | Prostate | None | ||
| 24246647 | 2014 | Short α-helical peptides | 18 | Linear | L | None | Amidation | Free | Antimicrobial | Alpha-helical proteins | HL-60 | Leukemia Cancer | MTT/MTS assay | 70% Cytotoxicity at 5 µM Approx | 24-h | Blood | None | ||
| 24246647 | 2014 | Short α-helical peptides | 14 | Linear | L | None | Amidation | Free | Antimicrobial | Alpha-helical proteins | HL-60 | Leukemia Cancer | MTT/MTS assay | 90% Cytotoxicity at 5 µM Approx | 24-h | Blood | None | ||
| 24246647 | 2014 | Short α-helical peptides | 10 | Linear | L | None | Amidation | Free | Antimicrobial | Alpha-helical proteins | HL-60 | Leukemia Cancer | MTT/MTS assay | 100% Cytotoxicity at 5 µM Approx | 24-h | Blood | None | ||
| 24246647 | 2014 | Short α-helical peptides | 14 | Linear | L | None | Amidation | Free | Antimicrobial | Alpha-helical proteins | HeLa | Cervical Cancer | MTT/MTS assay | 95% Cytotoxicity at 4 µM Approx | 24-h | Cervix | None | ||
| 24246647 | 2014 | Short α-helical peptides | 18 | Linear | L | None | Amidation | Free | Antimicrobial | Alpha-helical proteins | HeLa | Cervical Cancer | MTT/MTS assay | 80% Cytotoxicity at 4 µM Approx | 24-h | Cervix | None | ||
| 24246647 | 2014 | Short α-helical peptides | 10 | Linear | L | None | Amidation | Free | Antimicrobial | Alpha-helical proteins | HeLa | Cervical Cancer | MTT/MTS assay | 99% Cytotoxicity at 4 µM Approx | 24-h | Cervix | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | J774A.1 | Tumor | MTT/MTS assay | IC50=12 µM | 96-h | Blood | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | J774A.1 | Tumor | MTT/MTS assay | IC50=17 µM | 96-h | Blood | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | J774A.1 | Tumor | MTT/MTS assay | IC50=26 µM | 24-h | Blood | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | J774A.1 | Tumor | MTT/MTS assay | IC50=47 µM | 24-h | Blood | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | HUT-102 | Lymphoma Cancer | MTT/MTS assay | IC50=36 µM | 96-h | Blood | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | HUT-102 | Lymphoma Cancer | MTT/MTS assay | IC50=25 µM | 96-h | Blood | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | HUT-102 | Lymphoma Cancer | MTT/MTS assay | IC50=45 µM | 72-h | Blood | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | HUT-102 | Lymphoma Cancer | MTT/MTS assay | IC50=36 µM | 72-h | Blood | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | HUT-102 | Lymphoma Cancer | MTT/MTS assay | IC50=43 µM | 48-h | Blood | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | HUT-102 | Lymphoma Cancer | MTT/MTS assay | IC50=37 µM | 48-h | Blood | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | HUT-102 | Lymphoma Cancer | MTT/MTS assay | IC50=43 µM | 24-h | Blood | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | HUT-102 | Lymphoma Cancer | MTT/MTS assay | IC50=39 µM | 24-h | Blood | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | HUT-102 | Lymphoma Cancer | MTT/MTS assay | IC50=38 µM | 2-h | Blood | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | HUT-102 | Lymphoma Cancer | MTT/MTS assay | IC50=93 µM | 2-h | Blood | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | MDA-MB-231 | Breast Cancer | MTT/MTS assay | IC50=10 µM | 48-h | Breast | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | MDA-MB-231 | Breast Cancer | MTT/MTS assay | IC50=16 µM | 48-h | Breast | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | MDA-MB-231 | Breast Cancer | MTT/MTS assay | IC50=12 µM | 24-h | Breast | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | MDA-MB-231 | Breast Cancer | MTT/MTS assay | IC50=29 µM | 24-h | Breast | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | MDA-MB-231 | Breast Cancer | MTT/MTS assay | IC50=18 µM | 2-h | Breast | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | MDA-MB-231 | Breast Cancer | MTT/MTS assay | IC50=39 µM | 2-h | Breast | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | LNCaP | Prostate Cancer | MTT/MTS assay | IC50=8 µM | 48-h | Prostate | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | LNCaP | Prostate Cancer | MTT/MTS assay | IC50=28 µM | 48-h | Prostate | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | LNCaP | Prostate Cancer | MTT/MTS assay | IC50=23 µM | 24-h | Prostate | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | LNCaP | Prostate Cancer | MTT/MTS assay | IC50=9 µM | 24-h | Prostate | None | ||
| 23000474 | 2012 | 9R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | LNCaP | Prostate Cancer | MTT/MTS assay | IC50=44 µM | 2-h | Prostate | None | ||
| 23000474 | 2012 | 9S1R | 10 | Linear | L | None | Free | Free | Anticancer | Nullomer derived anticancer peptides (NulloPs): | LNCaP | Prostate Cancer | MTT/MTS assay | IC50=26 µM | 2-h | Prostate | None | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50 = 14.58 mM | 24-h | Ovary | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50 = 13.16 mM | 24-h | Skin | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 = 24.32 mM | 24-h | Prostate | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | NCI-H630 | Colon Cancer | MTT/MTS assay | IC50 = 57 mM | 24-h | Colon | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50 = 13.77 mM | 24-h | Stomach | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | HCTl-16 | Colon Cancer | MTT/MTS assay | IC50 = 14.8 mM | 24-h | Colon | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-549 | Lung Cancer | MTT/MTS assay | IC50 = 15.88 mM | 24-h | Lung | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-498 | Renal Cancer | MTT/MTS assay | Not Available | 24-h | Renal | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50 = 22.06 mM | 24-h | Ovary | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50 = 13.97 mM | 24-h | Skin | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 = 46.51 mM | 24-h | Prostate | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | NCI-H630 | Colon Cancer | MTT/MTS assay | IC50 = 48 mM | 24-h | Colon | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50 = 22.31 mM | 24-h | Stomach | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | HCTl-16 | Colon Cancer | MTT/MTS assay | IC50 = 24.63 mM | 24-h | Colon | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-549 | Lung Cancer | MTT/MTS assay | IC50 = 20.36 mM | 24-h | Lung | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-498 | Renal Cancer | MTT/MTS assay | Not Available | 24-h | Renal | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50 = 12.55 mM | 24-h | Ovary | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50 = 22.25 mM | 24-h | Skin | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 = 29.1 mM | 24-h | Prostate | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | NCI-H630 | Colon Cancer | MTT/MTS assay | Not Available | 24-h | Colon | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50 = 22.51 mM | 24-h | Stomach | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | HCTl-16 | Colon Cancer | MTT/MTS assay | IC50 = 14.8 mM | 24-h | Colon | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-549 | Lung Cancer | MTT/MTS assay | IC50 = 14.53 mM | 24-h | Lung | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-498 | Renal Cancer | MTT/MTS assay | IC50 = 21.48 mM | 24-h | Renal | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50 = 24.76 mM | 24-h | Ovary | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50 = 27.39 mM | 24-h | Skin | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 = 47.69 mM | 24-h | Prostate | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | NCI-H630 | Colon Cancer | MTT/MTS assay | Not Available | 24-h | Colon | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50 = 26.7 mM | 24-h | Stomach | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-549 | Lung Cancer | MTT/MTS assay | IC50 = 25.2 mM | 24-h | Lung | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-498 | Renal Cancer | MTT/MTS assay | IC50 = 41.21 mM | 24-h | Renal | WO_2007133033_A1 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | NCI-H630 | Colon Cancer | MTT/MTS assay | IC50 = 57 mM | 24-h | Colon | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | NCI-H630 | Colon Cancer | MTT/MTS assay | IC50 = 48 mM | 24-h | Colon | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | NCI-H630 | Colon Cancer | MTT/MTS assay | Not Available | 24-h | Colon | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | NCI-H630 | Colon Cancer | MTT/MTS assay | Not Available | 24-h | Colon | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | HCTl-16 | Colon Cancer | MTT/MTS assay | IC50 = 14.8 mM | 24-h | Colon | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | HCTl-16 | Colon Cancer | MTT/MTS assay | IC50 = 24.63 mM | 24-h | Colon | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | HCTl-16 | Colon Cancer | MTT/MTS assay | IC50 = 14.8 mM | 24-h | Colon | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | HCTl-16 | Colon Cancer | MTT/MTS assay | IC50 = 27 mM | 24-h | Colon | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-498 | Renal Cancer | MTT/MTS assay | Not Available | 24-h | Renal | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 = 24.32 mM | 24-h | Prostate | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50 = 13.77 mM | 24-h | Stomach | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50 = 14.58 mM | 24-h | Ovary | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-549 | Lung Cancer | MTT/MTS assay | IC50 = 14.8 mM | 24-h | Lung | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 4 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50 = 13.16 mM | 24-h | Skin | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-498 | Renal Cancer | MTT/MTS assay | Not Available | 24-h | Renal | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 = 46.51 mM | 24-h | Prostate | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50 = 24.31 mM | 24-h | Stomach | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50 = 22.06 mM | 24-h | Ovary | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-549 | Lung Cancer | MTT/MTS assay | IC50 = 20.36 mM | 24-h | Lung | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 3 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50 = 13.97 mM | 24-h | Skin | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-498 | Renal Cancer | MTT/MTS assay | IC50 = 21.48 mM | 24-h | Renal | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 = 29.1 mM | 24-h | Prostate | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50 = 22.51 mM | 24-h | Stomach | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50 = 12.55 mM | 24-h | Ovary | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-549 | Lung Cancer | MTT/MTS assay | IC50 = 14.53 mM | 24-h | Lung | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 2 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50 = 22.25 mM | 24-h | Skin | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-498 | Renal Cancer | MTT/MTS assay | IC50 = 41.21 mM | 24-h | Renal | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | PC-3 | Prostate Cancer | MTT/MTS assay | IC50 = 47.69 mM | 24-h | Prostate | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | MKN-45 | Gastric Cancer | MTT/MTS assay | IC50 = 26.7 mM | 24-h | Stomach | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-OV-3 | Ovarian Cancer | MTT/MTS assay | IC50 = 24.76 mM | 24-h | Ovary | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | SK-MEL-2 | Skin Cancer | MTT/MTS assay | IC50 = 27.39 mM | 24-h | Skin | US_008076284_B2 | ||
| None | 2011 | Gaegurin peptides SEQID NO: 1 | 11 | Linear | L | None | Free | Free | Antimicrobial | Korean frog Rana rugosa | A-549 | Lung Cancer | MTT/MTS assay | IC50 = 25.2 mM | 24-h | Lung | US_008076284_B2 | ||
| 22641352 | 2012 | RGD-Las | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | MEC | Breast Cancer | MTT/MTS assay | 29.33 Inhibition ratio at 50 µg/ml | 24-h | Breast | None | ||
| 22641352 | 2012 | RGD-La | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | MEC | Breast Cancer | MTT/MTS assay | 19.76 Inhibition ratio at 50 µg/ml | 24-h | Breast | None | ||
| 22641352 | 2012 | Temporin-Las | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | MEC | Breast Cancer | MTT/MTS assay | 27.99 Inhibition ratio at 50 µg/ml | 24-h | Breast | None | ||
| 22641352 | 2012 | Temporin-La | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | MEC | Breast Cancer | MTT/MTS assay | 24.15Inhibition ratio at 50 µg/ml | 24-h | Breast | None | ||
| 22641352 | 2012 | RGD-Las | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | HEK-293T | Renal Cancer | MTT/MTS assay | 32.52 Inhibition ratio at 50 µg/ml | 24-h | Renal | None | ||
| 22641352 | 2012 | RGD-La | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | HEK-293T | Renal Cancer | MTT/MTS assay | 27.86 Inhibition ratio at 50 µg/ml | 24-h | Renal | None | ||
| 22641352 | 2012 | Temporin-Las | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | HEK-293T | Renal Cancer | MTT/MTS assay | 30.90 Inhibition ratio at 50 µg/ml | 24-h | Renal | None | ||
| 22641352 | 2012 | Temporin-La | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | HEK-293T | Renal Cancer | MTT/MTS assay | 30.82 Inhibition ratio at 50 µg/ml | 24-h | Renal | None | ||
| 22641352 | 2012 | RGD-Las | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | HL7702 | Liver Cancer | MTT/MTS assay | 38.13 Inhibition ratio at 50 µg/ml | 24-h | Liver | None | ||
| 22641352 | 2012 | RGD-La | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | HL7702 | Liver Cancer | MTT/MTS assay | 36.25 Inhibition ratio at 50 µg/ml | 24-h | Liver | None | ||
| 22641352 | 2012 | Temporin-Las | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | HL7702 | Liver Cancer | MTT/MTS assay | 37.00 Inhibition ratio at 50 µg/ml | 24-h | Liver | None | ||
| 22641352 | 2012 | Temporin-La | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | HL7702 | Liver Cancer | MTT/MTS assay | 37.22 Inhibition ratio at 50 µg/ml | 24-h | Liver | None | ||
| 22641352 | 2012 | RGD-Las | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | A-549 | Lung Cancer | MTT/MTS assay | 52.50 Inhibition ratio at 50 µg/ml | 24-h | Lung | None | ||
| 22641352 | 2012 | RGD-La | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | A-549 | Lung Cancer | MTT/MTS assay | 47.26Inhibition ratio at 50 µg/ml | 24-h | Lung | None | ||
| 22641352 | 2012 | Temporin-Las | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | A-549 | Lung Cancer | MTT/MTS assay | 50.64 Inhibition ratio at 50 µg/ml | 24-h | Lung | None | ||
| 22641352 | 2012 | Temporin-La | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | A-549 | Lung Cancer | MTT/MTS assay | 45.62 Inhibition ratio at 50 µg/ml | 24-h | Lung | None | ||
| 22641352 | 2012 | RGD-Las | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | BGC-823 | Gastric Cancer | MTT/MTS assay | 73.705 Inhibition ratio at 50 µg/ml | 24-h | Stomach | None | ||
| 22641352 | 2012 | RGD-La | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | BGC-823 | Gastric Cancer | MTT/MTS assay | 62.49 Inhibition ratio at 50 µg/ml | 24-h | Stomach | None | ||
| 22641352 | 2012 | Temporin-Las | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | BGC-823 | Gastric Cancer | MTT/MTS assay | 50.85 Inhibition ratio at 50 µg/ml | 24-h | Stomach | None | ||
| 22641352 | 2012 | Temporin-La | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | BGC-823 | Gastric Cancer | MTT/MTS assay | 48.19 Inhibition ratio at 50 µg/ml | 24-h | Stomach | None | ||
| 22641352 | 2012 | RGD-Las | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide aNot Available temporins | HepG-2 | Liver Cancer | MTT/MTS assay | 73.07 Inhibition ratio at 50 µg/ml | 24-h | Liver | None | ||
| 22641352 | 2012 | RGD-La | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide aNot Available temporins | HepG-2 | Liver Cancer | MTT/MTS assay | 60.22 Inhibition ratio at 50 µg/ml | 24-h | Liver | None | ||
| 22641352 | 2012 | Temporin-Las | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | HepG-2 | Liver Cancer | MTT/MTS assay | 55.98 Inhibition ratio at 50 µg/ml | 24-h | Liver | None | ||
| 22641352 | 2012 | Temporin-La | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | HepG-2 | Liver Cancer | MTT/MTS assay | 50.90 Inhibition ratio at 50 µg/ml | 24-h | Liver | None | ||
| 22641352 | 2012 | RGD-Las | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | HeLa | Cervical Cancer | MTT/MTS assay | 78.045 Inhibition ratio at 50 µg/ml | 24-h | Cervix | None | ||
| 22641352 | 2012 | RGD-La | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | HeLa | Cervical Cancer | MTT/MTS assay | 73.09 Inhibition ratio at 50 µg/ml | 24-h | Cervix | None | ||
| 22641352 | 2012 | Temporin-Las | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | HeLa | Cervical Cancer | MTT/MTS assay | 56.81 Inhibition ratio at 50 µg/ml | 24-h | Cervix | None | ||
| 22641352 | 2012 | Temporin-La | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | HeLa | Cervical Cancer | MTT/MTS assay | 52.32 Inhibition ratio at 50 µg/ml | 24-h | Cervix | None | ||
| 22641352 | 2012 | RGD-Las | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | SMMC-7721 | Liver Cancer | MTT/MTS assay | 86.175 Inhibition ratio at 50 µg/ml | 24-h | Liver | None | ||
| 22641352 | 2012 | RGD-La | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | SMMC-7721 | Liver Cancer | MTT/MTS assay | 70.39 Inhibition ratio at 50 µg/ml | 24-h | Liver | None | ||
| 22641352 | 2012 | Temporin-Las | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | SMMC-7721 | Liver Cancer | MTT/MTS assay | 59.37 Inhibition ratio at 50 µg/ml | 24-h | Liver | None | ||
| 22641352 | 2012 | Temporin-La | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | SMMC-7721 | Liver Cancer | MTT/MTS assay | 52.77 Inhibition ratio at 50 µg/ml | 24-h | Liver | None | ||
| 22641352 | 2012 | RGD-Las | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | SW-1116 | Colorectal Cancer | MTT/MTS assay | 81.465 Inhibition ratio at 50 µg/ml | 24-h | Colon | None | ||
| 22641352 | 2012 | RGD-La | 16 | Linear | L | None | Free | Free | Anticancer | Arg-Gly-Asp(RGD) tripeptide ana temporins | SW-1116 | Colorectal Cancer | MTT/MTS assay | 72.69 Inhibition ratio at 50 µg/ml | 24-h | Colon | None | ||
| 22641352 | 2012 | Temporin-Las | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | SW-1116 | Colorectal Cancer | MTT/MTS assay | 62.73 Inhibition ratio at 50 µg/ml | 24-h | Colon | None | ||
| 22641352 | 2012 | Temporin-La | 13 | Linear | L | None | Free | Free | Anticancer | Temporins family | SW-1116 | Colorectal Cancer | MTT/MTS assay | 57.62 Inhibition ratio at 50 µg/ml | 24-h | Colon | None | ||
| 22073006 | 2011 | Pardaxin | 33 | Linear | L | None | Free | Free | Antibacterial | Red Sea Mosessole | HT-1080 | Fibrosarcoma | MTT/MTS assay | IC50=14.52 µg/ml | 24-h | Fibrous connective tissue | None | ||
| 22073006 | 2011 | Pardaxin | 33 | Linear | L | None | Free | Free | Antibacterial | Red Sea Mosessole | HT-1080 | Fibrosarcoma | MTT/MTS assay | IC50=14.51 µg/ml | 12-h | Fibrous connective tissue | None | ||
| 22073006 | 2011 | Pardaxin | 33 | Linear | L | None | Free | Free | Antibacterial | Red Sea Mosessole | HT-1080 | Fibrosarcoma | MTT/MTS assay | IC50=15.40 µg/ml | 6-h | Not Available | None | ||
| 22073006 | 2011 | Pardaxin | 33 | Linear | L | None | Free | Free | Antibacterial | Red Sea Mosessole | HT-1080 | Fibrosarcoma | MTT/MTS assay | IC50=15.74 µg/ml | 3-h | Not Available | None | ||
| 21252288 | 2011 | A12L/A20L/A23L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | HeLa | Cervical Cancer | MTT/MTS assay | IC50=2.2 µMo/L | 36-h | Cervix | None | ||
| 21252288 | 2011 | A12L/A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | HeLa | Cervical Cancer | MTT/MTS assay | IC50=2 µMo/L | 36-h | Cervix | None | ||
| 21252288 | 2011 | A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | HeLa | Cervical Cancer | MTT/MTS assay | IC50=4.3 µMo/L | 36-h | Cervix | None | ||
| 21252288 | 2011 | A12L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | HeLa | Cervical Cancer | MTT/MTS assay | IC50=3.8 µMo/L | 36-h | Cervix | None | ||
| 21252288 | 2011 | P | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | HeLa | Cervical Cancer | MTT/MTS assay | IC50=10.4 µMo/L | 36-h | Cervix | None | ||
| 21252288 | 2011 | L6A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | HeLa | Cervical Cancer | MTT/MTS assay | IC50=58.6 µMo/L | 36-h | Cervix | None | ||
| 21252288 | 2011 | L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | HeLa | Cervical Cancer | MTT/MTS assay | IC50=64.7 µMo/L | 36-h | Cervix | None | ||
| 21252288 | 2011 | L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | HeLa | Cervical Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Cervix | None | ||
| 21252288 | 2011 | L17A/L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | HeLa | Cervical Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Cervix | None | ||
| 21252288 | 2011 | L6A/L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | HeLa | Cervical Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Cervix | None | ||
| 21252288 | 2011 | A12L/A20L/A23L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | B-16 | Skin Cancer | MTT/MTS assay | IC50=4.6 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | A12L/A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | B-16 | Skin Cancer | MTT/MTS assay | IC50=4.4 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | B-16 | Skin Cancer | MTT/MTS assay | IC50=7.8 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | A12L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | B-16 | Skin Cancer | MTT/MTS assay | IC50=5.2 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | P | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | B-16 | Skin Cancer | MTT/MTS assay | IC50=11.5 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | L6A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | B-16 | Skin Cancer | MTT/MTS assay | IC50=62.5 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | B-16 | Skin Cancer | MTT/MTS assay | IC50=63.5 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | B-16 | Skin Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | L17A/L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | B-16 | Skin Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | L6A/L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | B-16 | Skin Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | A12L/A20L/A23L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | H-1299 | Lung Cancer | MTT/MTS assay | IC50=2.7 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | A12L/A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | H-1299 | Lung Cancer | MTT/MTS assay | IC50=4.1 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | H-1299 | Lung Cancer | MTT/MTS assay | IC50=2.9 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | A12L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | H-1299 | Lung Cancer | MTT/MTS assay | IC50=4.4 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | P | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | H-1299 | Lung Cancer | MTT/MTS assay | IC50=4.7 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | L6A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | H-1299 | Lung Cancer | MTT/MTS assay | IC50=14 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | H-1299 | Lung Cancer | MTT/MTS assay | IC50=15.6 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | H-1299 | Lung Cancer | MTT/MTS assay | IC50=16.4 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | L17A/L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | H-1299 | Lung Cancer | MTT/MTS assay | IC50=37.7 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | L6A/L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | H-1299 | Lung Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | A12L/A20L/A23L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | RD | Rhabdomyosarcoma Cancer | MTT/MTS assay | IC50=5.5 µMo/L | 36-h | Muscle | None | ||
| 21252288 | 2011 | A12L/A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | RD | Rhabdomyosarcoma Cancer | MTT/MTS assay | IC50=6.4 µMo/L | 36-h | Muscle | None | ||
| 21252288 | 2011 | A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | RD | Rhabdomyosarcoma Cancer | MTT/MTS assay | IC50=9.8 µMo/L | 36-h | Muscle | None | ||
| 21252288 | 2011 | A12L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | RD | Rhabdomyosarcoma Cancer | MTT/MTS assay | IC50=7.5 µMo/L | 36-h | Muscle | None | ||
| 21252288 | 2011 | P | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | RD | Rhabdomyosarcoma Cancer | MTT/MTS assay | IC50=25.2 µMo/L | 36-h | Muscle | None | ||
| 21252288 | 2011 | L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | RD | Rhabdomyosarcoma Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Muscle | None | ||
| 21252288 | 2011 | L6A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | RD | Rhabdomyosarcoma Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Muscle | None | ||
| 21252288 | 2011 | L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | RD | Rhabdomyosarcoma Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Muscle | None | ||
| 21252288 | 2011 | L17A/L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | RD | Rhabdomyosarcoma Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Muscle | None | ||
| 21252288 | 2011 | A12L/A20L/A23L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | SW-1116 | Colorectal Cancer | MTT/MTS assay | IC50=3.5 µMo/L | 36-h | Colon | None | ||
| 21252288 | 2011 | L6A/L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | RD | Rhabdomyosarcoma Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Muscle | None | ||
| 21252288 | 2011 | A12L/A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | SW-1116 | Colorectal Cancer | MTT/MTS assay | IC50=4.3 µMo/L | 36-h | Colon | None | ||
| 21252288 | 2011 | A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | SW-1116 | Colorectal Cancer | MTT/MTS assay | IC50=5 µMo/L | 36-h | Colon | None | ||
| 21252288 | 2011 | A12L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | SW-1116 | Colorectal Cancer | MTT/MTS assay | IC50=6.4 µMo/L | 36-h | Colon | None | ||
| 21252288 | 2011 | P | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | SW-1116 | Colorectal Cancer | MTT/MTS assay | IC50=11.1 µMo/L | 36-h | Colon | None | ||
| 21252288 | 2011 | L6A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | SW-1116 | Colorectal Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Colon | None | ||
| 21252288 | 2011 | L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | SW-1116 | Colorectal Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Colon | None | ||
| 21252288 | 2011 | L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | SW-1116 | Colorectal Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Colon | None | ||
| 21252288 | 2011 | L17A/L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | SW-1116 | Colorectal Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Colon | None | ||
| 21252288 | 2011 | L6A/L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | SW-1116 | Colorectal Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Colon | None | ||
| 21252288 | 2011 | A12L/A20L/A23L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=5.7 µMo/L | 36-h | Breast | None | ||
| 21252288 | 2011 | A12L/A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=6.2 µMo/L | 36-h | Breast | None | ||
| 21252288 | 2011 | A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=5.1 µMo/L | 36-h | Breast | None | ||
| 21252288 | 2011 | A12L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=5 µMo/L | 36-h | Breast | None | ||
| 21252288 | 2011 | P | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=15.8 µMo/L | 36-h | Breast | None | ||
| 21252288 | 2011 | L6A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=62.3 µMo/L | 36-h | Breast | None | ||
| 21252288 | 2011 | L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=70.8 µMo/L | 36-h | Breast | None | ||
| 21252288 | 2011 | L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Breast | None | ||
| 21252288 | 2011 | L17A/L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Breast | None | ||
| 21252288 | 2011 | L6A/L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | MCF-7 | Breast Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Breast | None | ||
| 21252288 | 2011 | A12L/A20L/A23L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-375 | Skin Cancer | MTT/MTS assay | IC50=7.2 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | A12L/A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-375 | Skin Cancer | MTT/MTS assay | IC50=8.7 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-375 | Skin Cancer | MTT/MTS assay | IC50=6.5 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | A12L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-375 | Skin Cancer | MTT/MTS assay | IC50=4.3 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | P | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-375 | Skin Cancer | MTT/MTS assay | IC50=17.8 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-375 | Skin Cancer | MTT/MTS assay | IC50=59.8 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | L6A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-375 | Skin Cancer | MTT/MTS assay | IC50=58.7 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | L6A/L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-375 | Skin Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | L17A/L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-375 | Skin Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-375 | Skin Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Skin | None | ||
| 21252288 | 2011 | A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-549 | Lung Cancer | MTT/MTS assay | IC50=8.7 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | A12L/A20L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-549 | Lung Cancer | MTT/MTS assay | IC50=9.7 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | A12L/A20L/A23L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-549 | Lung Cancer | MTT/MTS assay | IC50=9.2 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | L6A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-549 | Lung Cancer | MTT/MTS assay | IC50=53 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | P | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-549 | Lung Cancer | MTT/MTS assay | IC50=33 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | A12L | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-549 | Lung Cancer | MTT/MTS assay | IC50=11.1 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | L17A/L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-549 | Lung Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-549 | Lung Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | L21A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-549 | Lung Cancer | MTT/MTS assay | IC50=71 µMo/L | 36-h | Lung | None | ||
| 21252288 | 2011 | L6A/L17A | 26 | Linear | L | None | Free | Free | Anticancer | PeptideV13K | A-549 | Lung Cancer | MTT/MTS assay | IC50=>83.6 µMo/L | 36-h | Lung | None | ||
| 21955251 | 2011 | Cationic Amphiphilic | 21 | Cyclic | L | None | Free | Free | Antimicrobial | AMP | HL-60 | Pancreatic Cancer | WST-1 assay | IC50 = 10 µM | Not Available | Pancreatic | None | ||
| 21955251 | 2011 | Cationic Amphiphilic | 16 | Cyclic | L | None | Free | Free | Antimicrobial | AMP | HL-60 | Pancreatic Cancer | WST-1 assay | IC50 = 25 µM | Not Available | Pancreatic | None | ||
| 21955251 | 2011 | Cationic Amphiphilic | 11 | Cyclic | L | None | Free | Free | Antimicrobial | AMP | HL-60 | Pancreatic Cancer | WST-1 assay | IC50 = >500 µM | Not Available | Pancreatic | None | ||
| 21955251 | 2011 | Magainin 2 | 23 | Linear | L | None | Free | Free | Antimicrobial | Xenopus laevis | HeLa | Pancreatic Cancer | WST-1 assay | IC50 = >60 µM | Not Available | Pancreatic | None | ||
| 21955251 | 2011 | Cationic Amphiphilic | 21 | Cyclic | L | None | Free | Free | Antimicrobial | AMP | HeLa | Pancreatic Cancer | WST-1 assay | IC50 = 4 µM | Not Available | Pancreatic | None | ||
| 21955251 | 2011 | Cationic Amphiphilic | 16 | Cyclic | L | None | Free | Free | Antimicrobial | AMP | HeLa | Cervical Cancer | WST-1 assay | IC50 = 15 µM | Not Available | Cervix | None | ||
| 21955251 | 2011 | Cationic Amphiphilic | 11 | Cyclic | L | None | Free | Free | Antimicrobial | AMP | HeLa | Cervical Cancer | WST-1 assay | IC50 = 160 µM | Not Available | Cervix | None |