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| ID | PMID | YEAR | Sequence | Name | Length | Linear/Cyclic | Chirality | Chem-MOD | C-ter MOD | N-ter MOD | Nature | Origin | Cell Line | Cancer Type | Assay | Activity | Testing Time | Tissue Affected | Patents |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 38491556 | 2024 | HMM-ID | 34 | Linear | L | None | Free | Free | Anticancer | Red Sea Brine | U2OS | Osteosarcoma | MTT assay | IC50 = 100.5 µg/ml | 24-h | Bone | None | ||
| 31234333 | 2023 | LFB | 33 | Linear | L | None | Free | Free | Antimicrobial | Limnonectes fujianensis | HCT-116 | Colon Cancer | LDH leakage assay | LDH release above 80% | 24-h | Colon | None | ||
| 31234333 | 2023 | LFB | 33 | Linear | L | None | Free | Free | Antimicrobial | Limnonectes fujianensis | HCT-116 | Colon Cancer | MTT assay | IC50 = 2.02 μM | 24-h | Colon | None | ||
| 31234333 | 2023 | LFB | 33 | Linear | L | None | Free | Free | Antimicrobial | Limnonectes fujianensis | U-251-MG | Brain Tumor | MTT assay | IC50 = 2.32 μM | 24-h | Brain | None | ||
| 31234333 | 2023 | LFB | 33 | Linear | L | None | Free | Free | Antimicrobial | Limnonectes fujianensis | MDA-MB-435 | Breast Cancer | MTT assay | IC50 = 18.99 μM | 24-h | Breast | None | ||
| 31234333 | 2023 | LFB | 33 | Linear | L | None | Free | Free | Antimicrobial | Limnonectes fujianensis | H-460 | Lung Cancer | MTT assay | IC50 = 3.47 μM | 24-h | Lung | None | ||
| 36626098 | 2023 | LFchimera | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic - Lectoferrin chimera | Jurkat | Blood Cancer | MTT assay | cell viability ~ 8% at 20 µM | 6-h | Blood | None | ||
| 36626098 | 2023 | LFchimera | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Synthetic - Lectoferrin chimera | HepG-2 | Liver Cancer | MTT assay | cell viability ~ 44% at 10 µM | 12-h | Liver | None | ||
| 37344857 | 2023 | M1-21 | 31 | Linear | Mix | None | Free | Free | Anticancer | Synthetic | ZR-75-30 | Breast Cancer | Cell Viability assay | IC50 = 12.92 µM | 72-h | Breast | None | ||
| 37344857 | 2023 | M1-21 | 31 | Linear | Mix | None | Free | Free | Anticancer | Synthetic | U-251 | BrainTumor | Cell Viability assay | IC50 = 18.17 µM | 72-h | Brain | None | ||
| 37344857 | 2023 | M1-21 | 31 | Linear | Mix | None | Free | Free | Anticancer | Synthetic | A-549 | Lung Cancer | Cell Viability assay | IC50 = 22.00 µM | 72-h | Lung | None | ||
| 37344857 | 2023 | M1-21 | 31 | Linear | Mix | None | Free | Free | Anticancer | Synthetic | HCT-116 | Colon Cancer | Cell Viability assay | IC50 = 9.08 µM | 72-h | Colon | None | ||
| 37344857 | 2023 | M1-21 | 31 | Linear | Mix | None | Free | Free | Anticancer | Synthetic | 786-0 | Renal Cancer | Cell Viability assay | IC50 = 13.5 µM | 72-h | Renal | None | ||
| 37344857 | 2023 | M1-21 | 31 | Linear | Mix | None | Free | Free | Anticancer | Synthetic | HeLa | Cervical Cancer | Cell Viability assay | IC50 = 31.83 µM | 72-h | Cervix | None | ||
| 37344857 | 2023 | M1-21 | 31 | Linear | Mix | None | Free | Free | Anticancer | Synthetic | 5637 | Bladder cancer | Cell Viability assay | IC50 = 9.33 µM | 72-h | Bladder | None | ||
| 37344857 | 2023 | M1-21 | 31 | Linear | Mix | None | Free | Free | Anticancer | Synthetic | MDA-MB-231 | Breast Cancer | Cell Viability assay | IC50 = 24.25 µM | 72-h | Breast | None | ||
| 37495988 | 2023 | 37-mer peptide | 37 | Linear | L | None | Free | Free | Antimicrobial | Synthetic | SK-OV-3 | Ovarian cancer | MTT assay | IC50 = 27.45 ± 1.5085 μM | 24-h | Ovary | None | ||
| 37495988 | 2023 | 37-mer peptide | 37 | Linear | L | None | Free | Free | Antimicrobial | Synthetic | HepG-2 | Liver Cancer | MTT assay | IC50 = 33.65 ± 1.09 μM | 24-h | Liver | None | ||
| 37495988 | 2023 | 37-mer peptide | 37 | Linear | L | None | Free | Free | Antimicrobial | Synthetic | SNU-449 | Liver Cancer | MTT assay | IC50 = 76.4 ± 0.6015 μM | 24-h | Liver | None | ||
| 35246758 | 2022 | Nisin ZP | 34 | Cyclic | L | None | Cyclized | Cyclized | Antimicrobial | Lactococcus lactis | H-1299 | Lung Cancer | MTT assay | IC50 = 137.3 ± 9.1 μM | 48-h | Lung | None | ||
| 35246758 | 2022 | Nisin ZP | 34 | Cyclic | L | None | Cyclized | Cyclized | Antimicrobial | Lactococcus lactis | A-549 | Lung Cancer | MTT assay | IC50 = 132.4 ± 6.4 μM | 48-h | Lung | None | ||
| 36121385 | 2022 | ST101 | 38 | Linear | D | None | Free | Free | Anticancer | Synthetic | T98G | Brain Tumor | Annexin V/ PI staining assay | mean EC50 value of 2.1 ± 0.4 μmol/L | 48-h | Brain | None | ||
| 36121385 | 2022 | ST101 | 38 | Linear | D | None | Free | Free | Anticancer | Synthetic | A-549 | Lung Cancer | Annexin V/ PI staining assay | mean EC50 value of 2.1 ± 0.4 μmol/L | 48-h | Lung | None | ||
| 36121385 | 2022 | ST101 | 38 | Linear | D | None | Free | Free | Anticancer | Synthetic | DU-145 | Prostate Cancer | Annexin V/ PI staining assay | mean EC50 value of 2.1 ± 0.4 μmol/L | 48-h | Prostate | None | ||
| 36121385 | 2022 | ST101 | 38 | Linear | D | None | Free | Free | Anticancer | Synthetic | A-375 | Skin Cancer | Annexin V/ PI staining assay | mean EC50 value of 2.1 ± 0.4 μmol/L | 48-h | Skin | None | ||
| 36121385 | 2022 | ST101 | 38 | Linear | D | None | Free | Free | Anticancer | Synthetic | MCF-7 | Breast Cancer | Annexin V/ PI staining assay | mean EC50 value of 2.1 ± 0.4 μmol/L | 48-h | Breast | None | ||
| 36121385 | 2022 | ST101 | 38 | Linear | D | None | Free | Free | Anticancer | Synthetic | U-251 | Brain Tumor | Annexin V/ PI staining assay | mean EC50 value of 2.1 ± 0.4 μmol/L | 48-h | Brain | None | ||
| 34789753 | 2021 | Palustrin - Ca | 31 | Linear | L | None | Free | Free | Host Defence Peptide | Lithobates catesbeianus | SGC-7901 | Gastric Cancer | Not Available | IC50 = 0.951 μg/ml | Not Available | Stomach | None | ||
| 32381104 | 2021 | Sur-X | 35 | Linear | L | None | Free | TAT Peptide | Anticancer | Synthetic | HT-29 | Colon Cancer | MTT assay | Not Available | Not Available | Colon | None | ||
| 32381104 | 2021 | Sur-X | 35 | Linear | L | None | Free | TAT Peptide | Anticancer | Synthetic | RKO | Colon Cancer | MTT assay | 25% cell viability at at 20 μM | 24-h | Colon | None | ||
| 32381104 | 2021 | Sur-X | 35 | Linear | L | None | Free | TAT Peptide | Anticancer | Synthetic | HCT-15 | Colon Cancer | MTT assay | Not Available | Not Available | Colon | None | ||
| 32381104 | 2021 | Sur-X | 35 | Linear | L | None | Free | TAT Peptide | Anticancer | Synthetic | HCT-116 | Colon Cancer | MTT assay | 20% cell viability at at 20 μM | 24-h | Colon | None | ||
| 34309373 | 2021 | Pal-pFL-N-Ter-TAT | 32 | Linear | L | Dansylglycine = fluorescent amino acid residue located in the side chain of lysine | TAT | Palmitic acid; pFL - a hydrophobic peptide fragment (FPWWWPFL) rich in tryptophan (W) | Anticancer | Analogue of N-terminal fragment of the VDAC1 protein | MCF-7 | Breast Cancer | MTT assay | IC50 = 11.85 μM | 24-h | Breast | None | ||
| 34309373 | 2021 | Pal-pFL-N-Ter-TAT | 32 | Linear | L | Dansylglycine = fluorescent amino acid residue located in the side chain of lysine | TAT | Palmitic acid; pFL - a hydrophobic peptide fragment (FPWWWPFL) rich in tryptophan (W) | Anticancer | Analogue of N-terminal fragment of the VDAC1 protein | A-549 | Lung Cancer | MTT assay | IC50 = 31.17 μM | 24-h | Lung | None | ||
| 34309373 | 2021 | Pal-pFL-N-Ter-TAT | 32 | Linear | L | Dansylglycine = fluorescent amino acid residue located in the side chain of lysine | TAT | Palmitic acid; pFL - a hydrophobic peptide fragment (FPWWWPFL) rich in tryptophan (W) | Anticancer | Analogue of N-terminal fragment of the VDAC1 protein | A-375 | Skin Cancer | MTT assay | IC50 = 5.5 ± 1.1 μM | 24-h | Skin | None | ||
| 34309373 | 2021 | pFL-N-Ter-TAT | 32 | Linear | L | Dansylglycine = fluorescent amino acid residue located in the side chain of lysine | TAT | pFL = hydrophobic peptide fragment (FPWWWPFL) | Anticancer | Analogue of N-terminal fragment of the VDAC1 protein | A-375 | Skin Cancer | MTT assay | IC50 = 11.1 ± 0.1 μM | 24-h | Skin | None | ||
| 34073203 | 2021 | Ranatuerin-2 | 31 | Linear | L | None | Free | Free | Anticancer | Rana catesbeiana | LoVo | Colon Cancer | MTT assay | IC50 = 128 µM | 24-h | Colon | None | ||
| 34073203 | 2021 | Ranatuerin-2 | 31 | Linear | L | None | Free | Free | Anticancer | Rana catesbeiana | HeLa | Cervical Cancer | MTT assay | IC50 > 128 µM | 24-h | Cervix | None | ||
| 34073203 | 2021 | Ranatuerin-2 | 31 | Linear | L | None | Free | Free | Anticancer | Rana catesbeiana | MCF-7 | Breast Cancer | MTT assay | IC50 > 128 µM | 24-h | Breast | None | ||
| 34073203 | 2021 | Ranatuerin-2 | 31 | Linear | L | None | Free | Free | Anticancer | Rana catesbeiana | A-549 | Lung Cancer | MTT assay | IC50 > 128 µM | 24-h | Lung | None | ||
| 34073203 | 2021 | Brevinin-2DYb | 33 | Linear | L | None | Free | Free | Anticancer | Rana dybowskii | LoVo | Colon Cancer | MTT assay | IC50 = 35.05 µM | 24-h | Colon | None | ||
| 34073203 | 2021 | Brevinin-2DYb | 33 | Linear | L | None | Free | Free | Anticancer | Rana dybowskii | HeLa | Cervical Cancer | MTT assay | IC50 = 23.26 µM | 24-h | Cervix | None | ||
| 34073203 | 2021 | Brevinin-2DYb | 33 | Linear | L | None | Free | Free | Anticancer | Rana dybowskii | MCF-7 | Breast Cancer | MTT assay | IC50 = 37.84 µM | 24-h | Breast | None | ||
| 34073203 | 2021 | Brevinin-2DYb | 33 | Linear | L | None | Free | Free | Anticancer | Rana dybowskii | A-549 | Lung Cancer | MTT assay | IC50 = 24.01 µM | 24-h | Lung | None | ||
| 34073203 | 2021 | Odorranain-C1 | 33 | Linear | L | None | Free | Free | Anticancer | Odorrana grahami | LoVo | Colon Cancer | MTT assay | IC50 = 55.22 µM | 24-h | Colon | None | ||
| 34073203 | 2021 | Odorranain-C1 | 33 | Linear | L | None | Free | Free | Anticancer | Odorrana grahami | HeLa | Cervical Cancer | MTT assay | IC50 = 52.83 µM | 24-h | Cervix | None | ||
| 34073203 | 2021 | Odorranain-C1 | 33 | Linear | L | None | Free | Free | Anticancer | Odorrana grahami | MCF-7 | Breast Cancer | MTT assay | IC50 = 41.21 µM | 24-h | Breast | None | ||
| 34073203 | 2021 | Odorranain-C1 | 33 | Linear | L | None | Free | Free | Anticancer | Odorrana grahami | A-549 | Lung Cancer | MTT assay | IC50 = 27.31 µM | 24-h | Lung | None | ||
| 34073203 | 2021 | Ranatuerin-2Lb | 32 | Linear | L | None | Free | Free | Anticancer | Rana luteiventris | LoVo | Colon Cancer | MTT assay | IC50 = 59.78 µM | 24-h | Colon | None | ||
| 34073203 | 2021 | Ranatuerin-2Lb | 32 | Linear | L | None | Free | Free | Anticancer | Rana luteiventris | MCF-7 | Breast Cancer | MTT assay | IC50 = 45.25 µM | 24-h | Breast | None | ||
| 34073203 | 2021 | Ranatuerin-2Lb | 32 | Linear | L | None | Free | Free | Anticancer | Rana luteiventris | HeLa | Cervical Cancer | MTT assay | IC50 = 37.23 µM | 24-h | Cervix | None | ||
| 34073203 | 2021 | Ranatuerin-2Lb | 32 | Linear | L | None | Free | Free | Anticancer | Rana luteiventris | A-549 | Lung Cancer | MTT assay | IC50 = 15.32 µM | 24-h | Lung | None | ||
| 34073203 | 2021 | Brevinin-2DYd | 33 | Linear | L | None | Free | Free | Anticancer | Rana dybowskii | LoVo | Colon Cancer | MTT assay | IC50 = 8.05 µg/ml | 24-h | Colon | None | ||
| 34073203 | 2021 | Brevinin-2DYd | 33 | Linear | L | None | Free | Free | Anticancer | Rana dybowskii | HeLa | Cervical Cancer | MTT assay | IC50 = 19.69 µg/ml | 24-h | Cervix | None | ||
| 34073203 | 2021 | Brevinin-2DYd | 33 | Linear | L | None | Free | Free | Anticancer | Rana dybowskii | MCF-7 | Breast Cancer | MTT assay | IC50 = 25.74 µg/ml | 24-h | Breast | None | ||
| 34073203 | 2021 | Brevinin-2DYd | 33 | Linear | L | None | Free | Free | Anticancer | Rana dybowskii | A-549 | Lung Cancer | MTT assay | IC50 = 2.975 µg/ml | 24-h | Lung | None | ||
| 33029595 | 2020 | 4-arm branched peptide | 36 | Linear | L | thermal oxidation between the thiol group of cysteine residue in the two 2-arm branched | Free | Free | Antimicrobial | Synthetic | PC-3 | Prostate Cancer | MTT assay | Cell Viability (%) ~ 49.0 ± 0.8 at 30 µg/mL | 48-h | Prostate | None | ||
| 33029595 | 2020 | 4-arm branched peptide | 36 | Linear | L | thermal oxidation between the thiol group of cysteine residue in the two 2-arm branched | Free | Free | Antimicrobial | Synthetic | Bcap-37 | Breast Cancer | MTT assay | Cell Viability (%) ~ 51.4 ± 4.2 at 30 µg/mL | 48-h | Breast | None | ||
| 33029595 | 2020 | 4-arm branched peptide | 36 | Linear | L | thermal oxidation between the thiol group of cysteine residue in the two 2-arm branched | Free | Free | Antimicrobial | Synthetic | SK-HEP-1 | Liver Cancer | MTT assay | Cell Viability (%) ~ 31.7 ± 5.1 at 30 µg/mL | 48-h | Liver | None | ||
| 33029595 | 2020 | 4-arm branched peptide | 36 | Linear | L | thermal oxidation between the thiol group of cysteine residue in the two 2-arm branched | Free | Free | Antimicrobial | Synthetic | HCT-116 | Colon Cancer | MTT assay | Cell Viability (%) ~ 67.6 ± 5.8 at 30 µg/mL | 48-h | Colon | None | ||
| 31940927 | 2020 | Turgencin A | 36 | Cyclic(C8-C33,C12-C29,C17-C26) | L | None | Amidation | Free | Antimicrobial and Anticancer | Synoicum turgens | A-2058 | Skin Cancer | Cell Viability assay | IC50 1.4 µM | 72-h | Skin | None | ||
| 31940927 | 2020 | Turgencin B | 35 | Cyclic(C7-C31,C11-C27,C16-C24) | L | None | Amidation | Free | Antimicrobial and Anticancer | Synoicum turgens | A-2058 | Skin Cancer | Cell Viability assay | IC50 4.1 µM | 72-h | Skin | None | ||
| 33237335 | 2020 | MzDef | 34 | Linear | L | None | Free | Free | Antimicrobial and Anticancer | Zea mays L. | HCT-116 | Colon Cancer | MTT assay | IC50 = 29.85 µg/mL | 24-h | Colon | None | ||
| 33237335 | 2020 | MzDef | 34 | Linear | L | None | Free | Free | Antimicrobial and Anticancer | Zea mays L. | MCF-7 | Breast Cancer | MTT assay | IC50 = 14.85 µg/mL | 24-h | Breast | None | ||
| 33237335 | 2020 | MzDef | 34 | Linear | L | None | Free | Free | Antimicrobial and Anticancer | Zea mays L. | HepG-2 | Liver Cancer | MTT assay | IC50 ~ 22 µg/mL | 24-h | Liver | None | ||
| 30461197 | 2019 | Dermaseptin-PS1 | 31 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa sauvagei | U251-MG | Brain Tumor | LDH leakage assay | 20% LDH release at 10⁻⁴ M | 24-h | Brain | None | ||
| 30461197 | 2019 | Dermaseptin-PS1 | 31 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa sauvagei | U251-MG | Brain Tumor | MTT assay | 5.419 μmol/L | 24-h | Brain | None | ||
| 31234333 | 2019 | LFB | 33 | Linear | L | None | Free | Free | Antimicrobial | Limnonectes fujianensi | HCT-116 | Colon Cancer | MTT assay | IC50 = 2.02 µM | 24-h | Colon | None | ||
| 31234333 | 2019 | LFB | 33 | Linear | L | None | Free | Free | Antimicrobial | Limnonectes fujianensi | U251-MG | Brain Tumor | MTT assay | IC50 = 2.32 µM | 24-h | Brain | None | ||
| 31234333 | 2019 | LFB | 33 | Linear | L | None | Free | Free | Antimicrobial | Limnonectes fujianensi | MDA-MB-435S | Breast Cancer | MTT assay | IC50 = 18.99 µM | 24-h | Breast | None | ||
| 31234333 | 2019 | LFB | 33 | Linear | L | None | Free | Free | Antimicrobial | Limnonectes fujianensi | H-460 | Lung Cancer | MTT assay | IC50 = 3.47 µM | 24-h | Lung | None | ||
| 29628917 | 2018 | DLP-PH | 36 | Linear | L | None | Free | Free | Antimicrobial | Phyllomedusa hypochondrialis | PC-3 | Prostate Cancer | MTT assay | IC50 = 32.25 μg/mL | 24-h | Prostate | None | ||
| 29628917 | 2018 | DLP-PH | 36 | Linear | L | None | Free | Free | Antimicrobial | Phyllomedusa hypochondrialis | H-157 | Lung Cancer | MTT assay | IC50 = 15.41 μg/mL | 24-h | Lung | None | ||
| 30481557 | 2018 | PACAP38 | 38 | Linear | L | None | Amidation | Free | Antimicrobial and Anticancer | Clarias gariepinus | H-460 | Lung Cancer | Crystal Violet assay | IC50=14.97± 1.16 µM | 48-h | Lung | None | ||
| 30483133 | 2018 | myristoyl-CM4 | 36 | Linear | L | None | Amidation | N-myristoylation | Antimicrobial | Bombyx mori | MCF-7 | Breast cancer | MTT assay | IC50 = 6 μM | 24-h | Breast | None | ||
| 30483133 | 2018 | myristoyl-CM4 | 36 | Linear | L | None | Amidation | N-myristoylation | Antimicrobial | Bombyx mori | MDA-MB-231 | Breast cancer | MTT assay | IC50 = 4 μM | 24-h | Breast | None | ||
| 30483133 | 2018 | myristoyl-CM4 | 36 | Linear | L | None | Amidation | N-myristoylation | Antimicrobial | Bombyx mori | MX-1 | Breast cancer | MTT assay | IC50 = 3 μM | 24-h | Breast | None | ||
| 29875773 | 2018 | R11-NLS-pep8 | 38 | Linear | Mix | None | Free | Acetylation | Anticancer | NKp44 derived synthetic peptide | MDA-MD-231 | Breast Cancer | PrestoBlue assay | ED50 = 5.6 μM | 24-h | Breast | None | ||
| 29875773 | 2018 | R11-NLS-pep8 | 38 | Linear | Mix | None | Free | Acetylation | Anticancer | NKp44 derived synthetic peptide | HepG-2 | Liver Cancer | PrestoBlue assay | ED50 = 5.9 μM | 24-h | Liver | None | ||
| 29875773 | 2018 | R11-NLS-pep8 | 38 | Linear | Mix | None | Free | Acetylation | Anticancer | NKp44 derived synthetic peptide | PANC-1 | Pancreatic Cancer | PrestoBlue assay | ED50 = 7.8 μM | 24-h | Pancreas | None | ||
| 29875773 | 2018 | R11-NLS-pep8 | 38 | Linear | Mix | None | Free | Acetylation | Anticancer | NKp44 derived synthetic peptide | B-16 | Skin Cancer | PrestoBlue assay | ED50 = 7.1 μM | 24-h | Skin | None | ||
| 29054798 | 2018 | Nisin Z | 34 | Linear | L | None | Free | Free | Antimicrobial and Anticancer | Lactococcus lactis | A-375 | Skin Cancer | LDH leakage assay | 60% LDH release at 60 µM | 24-h | Skin | None | ||
| 29054798 | 2018 | Nisin Z | 34 | Linear | L | None | Free | Free | Antimicrobial and Anticancer | Lactococcus lactis | A-375 | Skin Cancer | MTT assay | IC50 = 188.5 ± 8.7 µM | 24-h | Skin | None | ||
| 28867631 | 2017 | Nisin Z | 34 | Cyclic | L | None | Cyclized | Cyclized | Antimicrobial | Lactococcus lactis | SW-480 | Colon Cancer | MTT assay | 79.22% cytotoxicity at 1000 μg/mL | 24-h | Colon | None | ||
| 28347740 | 2017 | ABP-dHC-Cecropin A-K(24) | 37 | Linear | L | None | Free | Free | Host Defence Peptide | Synthetic | THP-1 | Leukemia Cancer | MTT assay | IC50 = 196.1 μM | 24-h | Blood | None | ||
| 28347740 | 2017 | ABP-dHC-Cecropin A-K(24) | 37 | Linear | L | None | Free | Free | Host Defence Peptide | Synthetic | U-937 | Leukemia Cancer | MTT assay | IC50 = 223.9 μM | 24-h | Blood | None | ||
| 28347740 | 2017 | ABP-dHC-Cecropin A-K(24) | 37 | Linear | L | None | Free | Free | Host Defence Peptide | Synthetic | K-562 | Leukemia Cancer | MTT assay | IC50 = 184.9 μM | 24-h | Blood | None | ||
| 28347740 | 2017 | ABP-dHC-Cecropin A | 37 | Linear | L | None | Free | Free | Host Defence Peptide | Synthetic | THP-1 | Leukemia Cancer | MTT assay | IC50 = 228.5 μM | 24-h | Blood | None | ||
| 28347740 | 2017 | ABP-dHC-Cecropin A | 37 | Linear | L | None | Free | Free | Host Defence Peptide | Synthetic | U-937 | Leukemia Cancer | MTT assay | IC50 = 303.2 μM | 24-h | Blood | None | ||
| 28347740 | 2017 | ABP-dHC-Cecropin A | 37 | Linear | L | None | Free | Free | Host Defence Peptide | Synthetic | K-562 | Leukemia Cancer | MTT assay | IC50 = 349.5 μM | 24-h | Blood | None | ||
| 28157321 | 2017 | MccJ25-18-4 | 31 | Linear | Mix | x = Norleucine | Free | Free | Antimicrobial | Synthetic | MDA-MB-435-MDR | Breast Cancer | MTT assay | IC50 = 25.0 ± 0.5 μM | 48-h | Breast | None | ||
| 28157321 | 2017 | MccJ25-18-4 | 31 | Linear | Mix | x = Norleucine | Free | Free | Antimicrobial | Synthetic | MDA-MB-435 | Breast Cancer | MTT assay | IC50 = 20.0 ± 0.5 μM | 48-h | Breast | None | ||
| 28157321 | 2017 | MccJ25-18-4 | 31 | Linear | Mix | x = Norleucine | Free | Free | Antimicrobial | Synthetic | MCF-7 | Breast Cancer | MTT assay | IC50 = 14.2 ± 1.5 μM | 48-h | Breast | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | PC-3 | Prostate Cancer | LDH leakage assay | 100% cytotoxicity at 2.5 μM | 3-h | Prostate | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | LNCaP | Prostate Cancer | Crystal Violet assay | GI50 = 2.65 ± 1.09 μM | 24-h | Prostate | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | PC-3 | Prostate Cancer | Crystal Violet assay | GI50 = 2.17 ± 0.48 μM | 24-h | Prostate | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | DU-145 | Prostate Cancer | Crystal Violet assay | GI50 = 0.71 ± 0.55 μM | 24-h | Prostate | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | A-375 | Skin Cancer | Crystal Violet assay | GI50 > 10 μM | 24-h | Skin | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | SK-Mel-28 | Skin Cancer | Crystal Violet assay | GI50 > 10 μM | 24-h | Skin | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | HT-144 | Skin Cancer | Crystal Violet assay | GI50 = 5.08 ± 0.72 μM | 24-h | Skin | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | MIA PaCa-2 | Pancreatic Cancer | Crystal Violet assay | GI50 = 7.91 ± 1.40 μM | 24-h | Pancreas | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | BxPC-3 | Pancreatic Cancer | Crystal Violet assay | GI50 = 2.31 ± 0.41 μM | 24-h | Pancreas | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | PANC-1 | Pancreatic Cancer | Crystal Violet assay | GI50 > 10 μM | 24-h | Pancreas | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | MDA-MB-453 | Breast Cancer | Crystal Violet assay | GI50 > 10 μM | 24-h | Breast | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | BT-474 | Breast Cancer | Crystal Violet assay | GI50 > 10 μM | 24-h | Breast | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | MDA-MB-231 | Breast Cancer | Crystal Violet assay | GI50 > 10 μM | 24-h | Breast | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | U-373-MG | Brain Tumor | Crystal Violet assay | GI50 > 10 μM | 24-h | Brain | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | U-138-MG | Brain Tumor | Crystal Violet assay | GI50 > 10 μM | 24-h | Brain | None | ||
| 28797092 | 2017 | Dermaseptin - B2 | 33 | Linear | L | None | Amidation | Free | Antimicrobial | Phyllomedusa bicolor | U-87-MG | Brain Tumor | Crystal Violet assay | GI50 > 10 μM | 24-h | Brain | None | ||
| 26831010 | 2016 | CTX-23 | 36 | Linear | L | None | Free | Free | Anticancer | Synthetic | U-251 | Brain Tumor | MTT assay | Graph Figure 2 | 48-h | Brain | None | ||
| 26831010 | 2016 | CA4 | 35 | Linear | L | None | Free | Free | Anticancer | Synthetic | U-251 | Brain Tumor | MTT assay | Graph Figure 2 | 48-h | Brain | None | ||
| 27187467 | 2016 | dermaseptin-PD-2 | 33 | Linear | L | None | Free | Free | Antimicrobial | phyllomedusine leaf frogs,Pachymedusa dacnicolor | U251-MG | Brain Tumor | MTT assay | IC50 = 13.43 μM | 24-h | Brain | None | ||
| 27187467 | 2016 | dermaseptin-PD-2 | 33 | Linear | L | None | Free | Free | Antimicrobial | phyllomedusine leaf frogs,Pachymedusa dacnicolor | PC-3 | Prostate Cancer | MTT assay | IC50 = 3.17 μM | 24-h | Prostate | None | ||
| 27187467 | 2016 | dermaseptin-PD-2 | 33 | Linear | L | None | Free | Free | Antimicrobial | phyllomedusine leaf frogs,Pachymedusa dacnicolor | H-157 | Lung Cancer | MTT assay | IC50 = 6.43 μM | 24-h | Lung | None | ||
| 27187467 | 2016 | dermaseptin-PD-1 | 31 | Linear | L | None | Free | Free | Antimicrobial | phyllomedusine leaf frogs,Pachymedusa dacnicolor | U251-MG | Brain Tumor | MTT assay | IC50 = 15.08 μM | 24-h | Brain | None | ||
| 25821084 | 2015 | Ep-AMP1 | 35 | Cyclic | L | None | Cyclized | Cyclized | Antibacterial and Anticancer | Echinopsis pachanoi | U-937/GTB | Lymphoma cancer | Fluorometric microculture cytotoxicity assay | IC50 > 100 µM | Not Available | Blood | None | ||
| 26703631 | 2015 | Pardaxin | 33 | Linear | L | None | Free | Free | Antimicrobial | Pardachirus marmoratus | OSCC-SCC-4 | Oral cancer | MTT assay | Cell Viability <20% at 20μg/mL | 24-h | Not Available | None | ||
| 26064310 | 2015 | DC1 | 32 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | DU-145 | Liver Cancer | CCK-8 assay | IC50 = 3.32 μM | 72-h | Liver | None | ||
| 26064310 | 2015 | DC1 | 32 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | PC-3 | Prostate Cancer | CCK-8 assay | IC50 = 2.24 μM | 72-h | Prostate | None | ||
| 26064310 | 2015 | DC1 | 32 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | LNCaP | Prostate Cancer | CCK-8 assay | IC50 = 5.03 μM | 72-h | Prostate | None | ||
| 26064310 | 2015 | DC2 | 31 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | DU-145 | Liver Cancer | CCK-8 assay | IC50 = 3.11 μM | 72-h | Liver | None | ||
| 26064310 | 2015 | DC2 | 31 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | PC-3 | Prostate Cancer | CCK-8 assay | IC50 = 2.65 μM | 72-h | Prostate | None | ||
| 26064310 | 2015 | DC2 | 31 | Cyclic | L | None | Cyclized | Cyclized | Anticancer | Hedyotis diffusa | LNCaP | Prostate Cancer | CCK-8 assay | IC50 = 4.31 μM | 72-h | Prostate | None | ||
| 24661024 | 2014 | Cecropin A | 37 | Linear | L | None | Free | Free | Antimicrobial | Isolated from the giant silk moth Hyalophora cecropia | SCC25 | Skin Cancer | Cell Viability assay | 107.0 ± 5.0% cell growth inhibition at 1 µM | 24-h | Skin | None | ||
| 24661024 | 2014 | Cecropin A | 37 | Linear | L | None | Free | Free | Antimicrobial | Isolated from the giant silk moth Hyalophora cecropia | SCC25 | Skin Cancer | Cell Viability assay | 0.6 ± 0.6% cell growth inhibition at 10 µM | 48-h | Skin | None | ||
| 24661024 | 2014 | Cecropin A | 37 | Linear | L | None | Free | Free | Antimicrobial | Isolated from the giant silk moth Hyalophora cecropia | SCC25 | Skin Cancer | MTT/MTS assay | IC50=2.2 µM | 48-h | Skin | None | ||
| 24661024 | 2014 | Cecropin A | 37 | Linear | L | None | Free | Free | Antimicrobial | Isolated from the giant silk moth Hyalophora cecropia | SCC12 | Skin Cancer | MTT/MTS assay | IC50=1 µM | 48-h | Skin | None | ||
| 24587350 | 2014 | LL 37 | 37 | Linear | L | None | Free | Free | Antimicrobial | Also known human cathelicidin | OVRCAR-3 | Ovarian Cancer | MTT/MTS assay | LC50= 24 at 100 µM | 72-h | Ovary | None | ||
| 24587350 | 2014 | LL 37 | 37 | Linear | L | None | Free | Free | Antimicrobial | Also known human cathelicidin | LNCaP | Prostate cancer | MTT/MTS assay | LC50= 27 at 100 µM | 72-h | Prostate | None | ||
| 24587350 | 2014 | LL 37 | 37 | Linear | L | None | Free | Free | Antimicrobial | Also known human cathelicidin | MCF-7 | Breast Cancer | MTT/MTS assay | LC50= 21 at 100 µM | 72-h | Breast | None | ||
| 15496597 | 2004 | CB | 36 | Linear | L | None | Free | Free | Antibacterial | Synthetic | Ags | Gastric Cancer | Not Available | Not Available | Not Available | Stomach | None | ||
| 21351323 | 2011 | EGFR-lytic | 32 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | MDA-MB-231 | Breast Cancer | ELISA | IC50 =0.46 µM | 15-Min | Breast | None | ||
| 21351323 | 2011 | EGFR-lytic | 32 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | MDA-MB-231 | Breast Cancer | ELISA | IC50 =0.12 µM | 60-Min | Breast | None | ||
| 17561225, 18957441 | 2007 | Phylloseptin-L1 | 32 | Not Available | L | None | Free | Free | Anticancer | Hylomantis lemur (Hylidae: Phyllomedusinae | Not Available | Colorectal Cancer | Not Available | Not Available | Not Available | Not Available | None | ||
| 17561225, 18957441 | 2007 | Phylloseptin | 32 | Not Available | L | None | Free | Free | Anticancer | Hylomantis lemur (Hylidae: Phyllomedusinae | Not Available | Colorectal Cancer | Not Available | Not Available | Not Available | Not Available | None | ||
| 7628632, 18957441 | 1995 | hBD-1 | 36 | Not Available | L | None | Free | Free | Antibacterial | keratinocytes; skin; platelets;Homo sapiens | Not Available | Fibrosarcoma | Not Available | Not Available | Not Available | Fibrous connective tissue | None | ||
| 18191970, 18957441 | 2008 | Vibi H | 31 | Not Available | L | None | Free | Free | Anticancer | Alpine violetViola biflora | Not Available | Lung Cancer | Not Available | Not Available | Not Available | Not Available | None | ||
| 7916722, 18957441 | 1993 | Cecropin 2 | 39 | Not Available | L | None | Free | Free | Antibacterial | The Medfly, Ceratitis capitata; also housefly, Musca domestica | Not Available | Leukemia Cancer | Not Available | Not Available | Not Available | Not Available | None | ||
| 18191970, 18957441 | 2008 | Vibi G | 31 | Not Available | L | None | Free | Free | Anticancer | Alpine violetViola biflora | Not Available | Skin Cancer | Not Available | Not Available | Not Available | Not Available | None | ||
| 20575512, 18957441 | 2010 | Psyle E | 31 | Not Available | L | None | Free | Free | Antibacterial | Psychotria leptothyrsa | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21723349, 18957441 | 2011 | Viphi G | 31 | Not Available | L | None | Free | Free | Antibacterial | Viola philippica | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21723349, 18957441 | 2011 | Viphi F | 31 | Not Available | L | None | Free | Free | Antibacterial | Viola philippica | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21723349, 18957441 | 2011 | Viphi F | 31 | Not Available | L | None | Free | Free | Antibacterial | Viola philippica | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 21723349, 18957441 | 2011 | Viphi E | 31 | Not Available | L | None | Free | Free | Antibacterial | Viola philippica | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| 22467870, 18957441 | 2012 | Chassatide C2 | 32 | Not Available | L | None | Free | Free | Antibacterial | Chassalia chartacea | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | None | ||
| None | 2009 | Sema3A(aa363-377) -nLytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | SU.86.86 | Pancreatic Cancer | WST-1 assay | IC50= 7.9 µM | 48-h | Pancreatic | WO_2010_064207_A2 | ||
| None | 2009 | Sema3A(aa363-377) -nLytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | Pane- 1 | Breast Cancer | WST-1 assay | IC50= 13.1 µM | 48-h | Breast | WO_2010_064207_A2 | ||
| None | 2009 | Sema3A(aa363-377) -nLytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | CFPAC-I | Pancreatic Cancer | WST-1 assay | IC50= 10.6 µM | 48-h | Pancreatic | WO_2010_064207_A2 | ||
| None | 2009 | Sema3A(aa363-377) -nLytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | BxPC-3 | Pancreatic Cancer | WST-1 assay | IC50= 12.5 µM | 48-h | Pancreatic | WO_2010_064207_A2 | ||
| None | 2009 | EB(H2R)-lytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | LNCaP | Prostate Cancer | WST-1 assay | IC50= 4.8 µM | Not Available | Prostate | US_8436137_B2 | ||
| None | 2009 | EB(H2R)-lytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | SU.86.86 | Pancreatic Cancer | WST-1 assay | IC50= 7.4 µM | Not Available | Pancreatic | US_8436137_B2 | ||
| None | 2009 | EB(H2R)-lytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | BxPC-3 | Pancreatic Cancer | WST-1 assay | IC50= 6.6 µM | Not Available | Pancreatic | US_8436137_B2 | ||
| None | 2009 | EB(H2R)-lytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | U-251 | Brain Tumor | WST-1 assay | IC50= 8.4 µM | Not Available | Brain | US_8436137_B2 | ||
| None | 2009 | EB(H2R)-lytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | BT-20 | Breast Cancer | WST-1 assay | IC50= 1.9 µM | Not Available | Breast | US_8436137_B2 | ||
| None | 2009 | EB(H2R)-lytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | H-322 | Lung Cancer | WST-1 assay | IC50= 3.2 µM | Not Available | Lung | US_8436137_B2 | ||
| None | 2009 | EB-Lytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | LNCaP | Prostate Cancer | WST-1 assay | IC50= 10 µM | Not Available | Prostate | US_8436137_B2 | ||
| None | 2009 | EB-Lytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | SU.86.86 | Pancreatic Cancer | WST-1 assay | IC50= 12 µM | Not Available | Pancreatic | US_8436137_B2 | ||
| None | 2009 | EB-Lytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | BxPC-3 | Pancreatic Cancer | WST-1 assay | IC50= 12 µM | Not Available | Pancreatic | US_8436137_B2 | ||
| None | 2009 | EB-Lytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | U-251 | Brain Tumor | WST-1 assay | IC50= 12 µM | Not Available | Brain | US_8436137_B2 | ||
| None | 2009 | EB-Lytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | BT-20 | Breast Cancer | WST-1 assay | IC50= 6.5 µM | Not Available | Breast | US_8436137_B2 | ||
| None | 2009 | EB-Lytic | 32 | Linear | Mix | None | Free | Free | Anticancer | Synthetic Peptide | H-322 | Lung Cancer | WST-1 assay | IC50= 6.8 µM | Not Available | Lung | US_8436137_B2 | ||
| 16568093 | 2006 | r8-BadBH3 | 35 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | IMR5 | Tumor | MTT/MTS assay | 50% apoptosis at 50 µM | 8-h | Not Available | None | ||
| 16568093 | 2006 | r8-BadBH3 | 35 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | IMR5 | Tumor | MTT/MTS assay | 20% apoptosis at 20 µM | 8-h | Not Available | None | ||
| 16568093 | 2006 | r8-BadBH3 | 35 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | IMR5 | Tumor | MTT/MTS assay | 15% apoptosis at 10 µM | 8-h | Not Available | None | ||
| 16568093 | 2006 | r8-BadBH3 | 35 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | NGP | Tumor | MTT/MTS assay | 30% apoptosis at 50 µM | 8-h | Not Available | None | ||
| 16568093 | 2006 | r8-BadBH3 | 35 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | NGP | Tumor | MTT/MTS assay | >50% apoptosis at 20 µM | 8-h | Not Available | None | ||
| 16568093 | 2006 | r8-BadBH3 | 35 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | NGP | Tumor | MTT/MTS assay | 20% apoptosis at 10 µM | 8-h | Not Available | None | ||
| 16568093 | 2006 | r8-BadBH3 | 35 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | NB69 | Brain Tumor | MTT/MTS assay | 80% apoptosis at 50 µM | 8-h | Brain | None | ||
| 16568093 | 2006 | r8-BadBH3 | 35 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | NB69 | Brain Tumor | MTT/MTS assay | 80% apoptosis at 20 µM | 8-h | Brain | None | ||
| 16568093 | 2006 | r8-BadBH3 | 35 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | NB69 | Brain Tumor | MTT/MTS assay | 30% apoptosis at 10 µM | 8-h | Brain | None | ||
| 16568093 | 2006 | r8-BadBH3 | 35 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | SK-N-AS | Brain Tumor | MTT/MTS assay | 30% apoptosis at 50 µM | 8-h | Brain | None | ||
| 16568093 | 2006 | r8-BadBH3 | 35 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | SK-N-AS | Brain Tumor | MTT/MTS assay | 10% apoptosis at 20 µM | 8-h | Brain | None | ||
| 16568093 | 2006 | r8-BadBH3 | 35 | Linear | Mix | None | Free | Free | Antitumor | Synthetic Peptide | SK-N-AS | Brain Tumor | MTT/MTS assay | 0% apoptosis at 10 µM | 8-h | Brain | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | MOLT-4 | Leukemia Cancer | MTT/MTS assay | ED50 =0.29 µM | 24-h | Blood | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | PTC | Colon Cancer | MTT/MTS assay | ED50 >10 µM | 24-h | Colon | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | MiaPaCa.2 | Pancreatic Cancer | MTT/MTS assay | ED50 =0.210 µM | 24-h | Pancreatic | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | KB | Oral Cancer | MTT/MTS assay | ED50 =2.1 µM | 24-h | Oral mucosa | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | MOLT-4 | Leukemia Cancer | MTT/MTS assay | 94.5 % inhibition of cell proliferation at 10 µM | 24-h | Blood | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | MOLT-4 | Leukemia Cancer | MTT/MTS assay | 54.3 % inhibition of cell proliferation at 1 µM | 24-h | Blood | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | MOLT-4 | Leukemia Cancer | MTT/MTS assay | 34.7 % inhibition of cell proliferation at 100 nM | 72-h | Blood | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | MOLT-4 | Leukemia Cancer | MTT/MTS assay | 18.7 % inhibition of cell proliferation at 10 nM | 24-h | Blood | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | MOLT-4 | Leukemia Cancer | MTT/MTS assay | 10.4 % inhibition of cell proliferation at 1 nM | 24-h | Blood | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | PTC | Colon Cancer | MTT/MTS assay | 27.9 % inhibition of cell proliferation at 10 µM | 24-h | Colon | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | PTC | Colon Cancer | MTT/MTS assay | 21.7 % inhibition of cell proliferation at 1 µM | 24-h | Colon | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | PTC | Colon Cancer | MTT/MTS assay | 16.8 % inhibition of cell proliferation at 100 nM | 72-h | Colon | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | PTC | Colon Cancer | MTT/MTS assay | 14.2 % inhibition of cell proliferation at 10 nM | 24-h | Colon | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | PTC | Colon Cancer | MTT/MTS assay | 16.5 % inhibition of cell proliferation at 1 nM | 24-h | Colon | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | MiaPaCa.2 | Pancreatic Cancer | MTT/MTS assay | 84.5 % inhibition of cell proliferation at 10 µM | 24-h | Pancreatic | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | MiaPaCa.2 | Pancreatic Cancer | MTT/MTS assay | 59.6 % inhibition of cell proliferation at 1 µM | 24-h | Pancreatic | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | MiaPaCa.2 | Pancreatic Cancer | MTT/MTS assay | 48.2 % inhibition of cell proliferation at 100 nM | 72-h | Pancreatic | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | MiaPaCa.2 | Pancreatic Cancer | MTT/MTS assay | 37.8 % inhibition of cell proliferation at 10 nM | 24-h | Pancreatic | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | MiaPaCa.2 | Pancreatic Cancer | MTT/MTS assay | 24.2 % inhibition of cell proliferation at 1 nM | 24-h | Pancreatic | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | KB | Oral Cancer | MTT/MTS assay | 98.3 % inhibition of cell proliferation at 10 µM | 24-h | Oral mucosa | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | KB | Oral Cancer | MTT/MTS assay | 43.1 % inhibition of cell proliferation at 1 µM | 24-h | Oral mucosa | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | KB | Oral Cancer | MTT/MTS assay | 30.7 % inhibition of cell proliferation at 100 nM | 72-h | Oral mucosa | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | KB | Oral Cancer | MTT/MTS assay | 18.2 % inhibition of cell proliferation at 10 nM | 24-h | Oral mucosa | None | ||
| 17559067 | 2007 | Peptide 5 | 40 | Linear | Mix | Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen | Amidation | Free | Anticancer | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin, substance P a | KB | Oral Cancer | MTT/MTS assay | 10.6 % inhibition of cell proliferation at 1 nM | 24-h | Oral mucosa | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 10 % Cytotoxicity at 3.125 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 5 % Cytotoxicity at 6.25 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 25 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 15 % Cytotoxicity at 12.5 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 50 mg/L | 24-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 38 % Cytotoxicity at 3.125 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 39 % Cytotoxicity at 12.5 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 28 % Cytotoxicity at 6.25 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 95 % Cytotoxicity at 25 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 30 % Cytotoxicity at 3.125 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 97 % Cytotoxicity at 50 mg/L | 12-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 30 % Cytotoxicity at 6.25 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 30 % Cytotoxicity at 12.5 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 25 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 90 % Cytotoxicity at 50 mg/L | 6-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 35 % Cytotoxicity at 3.125 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 35 % Cytotoxicity at 6.25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 40 % Cytotoxicity at 12.5 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 82 % Cytotoxicity at 25 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HT-1080 | Fibrosarcoma | MTT/MTS assay | 88 % Cytotoxicity at 50 mg/L | 3-h | Fibrous connective tissue | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 5 % Cytotoxicity at 3.125 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 12 % Cytotoxicity at 6.25 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 15 % Cytotoxicity at 12.5 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 80 % Cytotoxicity at 25 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 90 % Cytotoxicity at 50 mg/L | 24-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 10 % Cytotoxicity at 3.125 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 5 % Cytotoxicity at 6.25 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 4 % Cytotoxicity at 12.5 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 68 % Cytotoxicity at 25 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 78 % Cytotoxicity at 50 mg/L | 12-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 4 % Cytotoxicity at 3.125 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 70 % Cytotoxicity at 25 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 75 % Cytotoxicity at 50 mg/L | 6-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 4 % Cytotoxicity at 12.5 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 44 % Cytotoxicity at 25 mg/L | 3-h | Cervix | None | ||
| 23598079 | 2013 | Pardaxin-1 | 33 | Linear | L | None | Free | Free | Antimicrobial | Epinephelus nebulosus | HeLa | Cervical Cancer | MTT/MTS assay | 62 % Cytotoxicity at 50 mg/L | 3-h | Cervix | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | COLO-587 | Human epithelial Cancer | WST-1 assay | IC50=6.4 µM | 72-h | Pancreatic | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | LNCaP | Prostate Cancer | WST-1 assay | IC50= 6.2 µM | 72-h | Prostate | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | HuCCT-1 | Human epithelial Cancer | WST-1 assay | IC50= 8.3 µM | 72-h | Bileduct | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | U-251 | Brain Tumor | WST-1 assay | IC50=7.0 µM | 72-h | Brain | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | SN-19 | Brain Tumor | WST-1 assay | IC50= 7.8 µM | 72-h | Brain | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | SF-295 | Brain Tumor | WST-1 assay | IC50= 6.3 µM | 72-h | Brain | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | ZR75-1 | Breast Cancer | WST-1 assay | IC50= 9.3 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | BT-20 | Breast Cancer | WST-1 assay | IC50= 4.8 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | MDA-MB-231 | Breast Cancer | WST-1 assay | IC50= 7.8 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | SK-BR-3 | Breast Cancer | WST-1 assay | IC50= 6.5 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | T-47D | Breast Cancer | WST-1 assay | IC50= 4.0 µM | 72-h | Breast | None | ||
| 21849092 | 2011 | Transferrin receptor (TfR)-lytic hybrid peptide | 32 | Linear | Mix | None | Free | Free | Anticancer | Transferrin receptor (TfR) | BT-474 | Breast Cancer | WST-1 assay | IC50= 8.8 µM | 72-h | Breast | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | MDA-MB-231 | Breast Cancer | WST-1 assay | IC50=5.7 µMol/L | 24-h | Breast | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | H-322 | Lung Cancer | WST-1 assay | IC50=3.6 µMol/L | 24-h | Lung | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | A-172 | Brain Tumor | WST-1 assay | IC50=6.8 µMol/L | 24-h | Brain | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | T98G | Brain Tumor | WST-1 assay | IC50=18.5 µMol/L | 24-h | Brain | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Bovine lactoferrin (Lf-B) | KB | Oral Cancer | WST-1 assay | IC50=13.2 µMol/L | 24-h | Oral mucosa | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | SU.86.86 | Pancreatic Cancer | WST-1 assay | IC50=7.5 µMol/L | 24-h | Pancreatic | None | ||
| 22084165 | 2011 | IL-4RaÐlytic hybrid peptide | 33 | Linear | Mix | None | Free | Free | Anticancer | Interleukin-4 receptor a (IL-4Ra) chain | BXPC-3 | Pancreatic Cancer | WST-1 assay | IC50=6.8 µMol/L | 24-h | Pancreatic | None | ||
| 23028527 | 2012 | Adenoregulin | 33 | Linear | L | None | Free | Free | Antimicrobial | South American frog Phyllomedusa bicolor | Raji | Lymphoma Cancer | LDH leakage assay | GI50 =2.57±0.75 µM | 24-h | Blood | None | ||
| 23028527 | 2012 | Adenoregulin | 33 | Linear | L | None | Free | Free | Antimicrobial | South American frog Phyllomedusa bicolor | MDA-MB-231 | Breast Cancer | LDH leakage assay | GI50 =8.06±0.50 µM | 24-h | Breast | None | ||
| 23028527 | 2012 | Adenoregulin | 33 | Linear | L | None | Free | Free | Antimicrobial | South American frog Phyllomedusa bicolor | DU-145 | Liver Cancer | LDH leakage assay | GI50 =0.91±0.04 µM | 24-h | Prostate | None | ||
| 23028527 | 2012 | Adenoregulin | 33 | Linear | L | None | Free | Free | Antimicrobial | South American frog Phyllomedusa bicolor | LNCaP | Prostate Cancer | LDH leakage assay | GI50 =0.31±0.15 µM | 24-h | Prostate | None | ||
| 23028527 | 2012 | Adenoregulin | 33 | Linear | L | None | Free | Free | Antimicrobial | South American frog Phyllomedusa bicolor | PC-3 | Prostate Cancer | LDH leakage assay | GI50 =1.24±0.23 µM | 24-h | Prostate | None | ||
| None | 2005 | LSB-37 | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | HeLa | Cervical Cancer | MTT/MTS assay | LD50 =250 µg/ml | 24-h | Cervix | US_06875744_B2 | ||
| None | 2005 | Shiva-11 | 31 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | HeLa | Cervical Cancer | MTT/MTS assay | LD50 =175 µg/ml | 24-h | Cervix | US_06875744_B2 | ||
| None | 2005 | SB-37 AM | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | HeLa | Cervical Cancer | MTT/MTS assay | LD50 =>1000 µg/ml | 24-h | Cervix | US_06875744_B2 | ||
| None | 2005 | SB-37 AC | 38 | Linear | L | None | Free | Free | Anticancer | FLAK peptides | HeLa | Cervical Cancer | MTT/MTS assay | LD50 =150 µg/ml | 24-h | Cervix | US_06875744_B2 | ||
| None | 2005 | LSB-37 | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | PC-3 | Prostate Cancer | MTT/MTS assay | LD50 =370 µg/ml | 24-h | Prostate | US_06875744_B2 | ||
| None | 2005 | Shiva-11 | 31 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | PC-3 | Prostate Cancer | MTT/MTS assay | LD50 =52 µg/ml | 24-h | Prostate | US_06875744_B2 | ||
| None | 2005 | SB-37 AC | 38 | Linear | L | None | Free | Free | Anticancer | FLAK peptides | PC-3 | Prostate Cancer | MTT/MTS assay | Not Available | 24-h | Prostate | US_06875744_B2 | ||
| None | 2005 | SB-37 AM | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | PC-3 | Prostate Cancer | MTT/MTS assay | LD50 =630 µg/ml | 24-h | Prostate | US_06875744_B2 | ||
| None | 2005 | LSB-37 | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | H-1299 | Lung Cancer | MTT/MTS assay | LD50 =120 µg/ml | 24-h | Lung | US_06875744_B2 | ||
| None | 2005 | Shiva-11 | 31 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | H-1299 | Lung Cancer | MTT/MTS assay | LD50 =53 µg/ml | 24-h | Lung | US_06875744_B2 | ||
| None | 2005 | SB-37 AM | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | H-1299 | Lung Cancer | MTT/MTS assay | LD50 =720 µg/ml | 24-h | Lung | US_06875744_B2 | ||
| None | 2005 | SB-37 AC | 38 | Linear | L | None | Free | Free | Anticancer | FLAK peptides | H-1299 | Lung Cancer | MTT/MTS assay | LD50 =220 µg/ml | 24-h | Lung | US_06875744_B2 | ||
| None | 2005 | LSB-37 | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | BMKC | Skin Cancer | MTT/MTS assay | LD50 =170 µg/ml | 24-h | Skin | US_06875744_B2 | ||
| None | 2005 | Shiva-11 | 31 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | BMKC | Skin Cancer | MTT/MTS assay | LD50 =94 µg/ml | 24-h | Skin | US_06875744_B2 | ||
| None | 2005 | SB-37 AC | 38 | Linear | L | None | Free | Free | Anticancer | FLAK peptides | BMKC | Skin Cancer | MTT/MTS assay | LD50 =120 µg/ml | 24-h | Skin | US_06875744_B2 | ||
| None | 2005 | SB-37 AM | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | BMKC | Skin Cancer | MTT/MTS assay | LD50 =>1000 µg/ml | 24-h | Skin | US_06875744_B2 | ||
| None | 2005 | LSB-37 | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | BMKC | Skin Cancer | MTT/MTS assay | LD50 =170 µg/ml | 24-h | Skin | US_06875744_B2 | ||
| None | 2005 | Shiva-11 | 31 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | BMKC | Skin Cancer | MTT/MTS assay | LD50 =94 µg/ml | 24-h | Skin | US_06875744_B2 | ||
| None | 2005 | SB-37 AM | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | BMKC | Skin Cancer | MTT/MTS assay | LD50 =>1000 µg/ml | 24-h | Skin | US_06875744_B2 | ||
| None | 2005 | SB-37 AC | 38 | Linear | L | None | Free | Free | Anticancer | FLAK peptides | BMKC | Skin Cancer | MTT/MTS assay | LD50 =120 µg/ml | 24-h | Skin | US_06875744_B2 | ||
| None | 2005 | LSB-37 | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | SW-480 | Colon Cancer | MTT/MTS assay | LD50 =240 µg/ml | 24-h | Colon | US_06875744_B2 | ||
| None | 2005 | Shiva-11 | 31 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | SW-480 | Colon Cancer | MTT/MTS assay | LD50 =125 µg/ml | 24-h | Colon | US_06875744_B2 | ||
| None | 2005 | SB-37 AM | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | SW-480 | Colon Cancer | MTT/MTS assay | LD50 =>1000 µg/ml | 24-h | Colon | US_06875744_B2 | ||
| None | 2005 | SB-37 AC | 38 | Linear | L | None | Free | Free | Anticancer | FLAK peptides | SW-480 | Colon Cancer | MTT/MTS assay | LD50 =82 µg/ml | 24-h | Colon | US_06875744_B2 | ||
| None | 2005 | LSB-37 | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | MCF-7 | Breast Cancer | MTT/MTS assay | LD50 =50 µg/ml | 24-h | Breast | US_06875744_B2 | ||
| None | 2005 | Shiva-11 | 31 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | MCF-7 | Breast Cancer | MTT/MTS assay | LD50 =96 µg/ml | 24-h | Breast | US_06875744_B2 | ||
| None | 2005 | SB-37 AM | 38 | Linear | L | None | Amidation | Free | Anticancer | FLAK peptides | MCF-7 | Breast Cancer | MTT/MTS assay | LD50 =540 µg/ml | 24-h | Breast | US_06875744_B2 | ||
| None | 2005 | SB-37 AC | 38 | Linear | L | None | Free | Free | Anticancer | FLAK peptides | MCF-7 | Breast Cancer | MTT/MTS assay | LD50 =175 µg/ml | 24-h | Breast | US_06875744_B2 | ||
| 9614066 | 1998 | DRS S1 | 35 | Linear | L | None | Free | Free | Antimicrobial | Dermaseptins B | MCF-7 | Breast Cancer | Thymidine Incorporation assay | Not Available | 6-h | Breast | None | ||
| 22073006 | 2011 | Pardaxin | 33 | Linear | L | None | Free | Free | Antibacterial | Red Sea Mosessole | HT-1080 | Fibrosarcoma | MTT/MTS assay | IC50=14.52 µg/ml | 24-h | Fibrous connective tissue | None | ||
| 22073006 | 2011 | Pardaxin | 33 | Linear | L | None | Free | Free | Antibacterial | Red Sea Mosessole | HT-1080 | Fibrosarcoma | MTT/MTS assay | IC50=14.51 µg/ml | 12-h | Fibrous connective tissue | None | ||
| 22073006 | 2011 | Pardaxin | 33 | Linear | L | None | Free | Free | Antibacterial | Red Sea Mosessole | HT-1080 | Fibrosarcoma | MTT/MTS assay | IC50=15.40 µg/ml | 6-h | Not Available | None | ||
| 22073006 | 2011 | Pardaxin | 33 | Linear | L | None | Free | Free | Antibacterial | Red Sea Mosessole | HT-1080 | Fibrosarcoma | MTT/MTS assay | IC50=15.74 µg/ml | 3-h | Not Available | None | ||
| 18315881 | 2008 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese oak silk moth | J82 | Bladder Cancer | LDH leakage assay | Cytotoxicity=196.3 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese oak silk moth | 647V | Bladder Cancer | LDH leakage assay | IC50=181.1 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese oak silk moth | RT4 | Bladder Cancer | LDH leakage assay | IC50=240.4 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese oak silk moth | 486P | Bladder Cancer | LDH leakage assay | IC50=232.4 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin A | 37 | Linear | L | None | Amidation | Free | Antimicrobial | Hyalophora Cecropia(silkmoth) | J82 | Bladder Cancer | LDH leakage assay | IC50=319.2 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin A | 37 | Linear | L | None | Amidation | Free | Antimicrobial | Hyalophora Cecropia(silkmoth) | 647V | Bladder Cancer | LDH leakage assay | IC50=200.7 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin A | 37 | Linear | L | None | Amidation | Free | Antimicrobial | Hyalophora Cecropia(silkmoth) | RT4 | Bladder Cancer | LDH leakage assay | IC50=289.3 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin A | 37 | Linear | L | None | Amidation | Free | Antimicrobial | Hyalophora Cecropia(silkmoth) | 486P | Bladder Cancer | LDH leakage assay | IC50=373.3/ µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese oak silk moth | J82 | Bladder Cancer | Cell Viability assay | IC50=77.51 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese oak silk moth | 647V | Bladder Cancer | Cell Viability assay | IC50=61.86 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese oak silk moth | RT4 | Bladder Cancer | Cell Viability assay | IC50=92.9 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese oak silk moth | 486P | Bladder Cancer | Cell Viability assay | IC50=87.47 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin A | 37 | Linear | L | None | Amidation | Free | Antimicrobial | Hyalophora Cecropia(silkmoth) | J82 | Bladder Cancer | Cell Viability assay | IC50=99.01 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin A | 37 | Linear | L | None | Amidation | Free | Antimicrobial | Hyalophora Cecropia(silkmoth) | 647V | Bladder Cancer | Cell Viability assay | IC50=28.74 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin A | 37 | Linear | L | None | Amidation | Free | Antimicrobial | Hyalophora Cecropia(silkmoth) | RT4 | Bladder Cancer | Cell Viability assay | IC50=96.22 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin A | 37 | Linear | L | None | Amidation | Free | Antimicrobial | Hyalophora Cecropia(silkmoth) | 486P | Bladder Cancer | Cell Viability assay | IC50=69.2 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese oak silk moth | J82 | Bladder Cancer | WST-1 assay | IC50=97.93 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese oak silk moth | 647V | Bladder Cancer | WST-1 assay | IC50=115.12 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese oak silk moth | RT4 | Bladder Cancer | WST-1 assay | IC50=184.81 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antimicrobial | Chinese oak silk moth | 486P | Bladder Cancer | WST-1 assay | IC50=161.76 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin A | 37 | Linear | L | None | Amidation | Free | Antimicrobial | Hyalophora Cecropia(silkmoth) | J82 | Bladder Cancer | WST-1 assay | IC50=212.07 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin A | 37 | Linear | L | None | Amidation | Free | Antimicrobial | Hyalophora Cecropia(silkmoth) | 647V | Bladder Cancer | WST-1 assay | IC50=185.39 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin A | 37 | Linear | L | None | Amidation | Free | Antimicrobial | Hyalophora Cecropia(silkmoth) | RT4 | Bladder Cancer | WST-1 assay | IC50=231.26 µg/ml | 48-h | Bladder | None | ||
| 18315881 | 2008 | Cecropin A | 37 | Linear | L | None | Amidation | Free | Antimicrobial | Hyalophora Cecropia(silkmoth) | 486P | Bladder Cancer | WST-1 assay | IC50=251.47 µg/ml | 48-h | Bladder | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | MCF-7R | Breast Cancer | MTT assay | IC50=24.5 | 96-h | Breast | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | A-2780R | Ovarian Cancer | MTT assay | IC50=34.5 | 96-h | Ovary | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | HT-29 | Colon Cancer | MTT assay | IC50=>100 µM | 96-h | Colon | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | MCF-7 | Breast Cancer | MTT assay | IC50=42.5 µM | 96-h | Breast | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | MAC15A | Colon Cancer | MTT assay | IC50=37 µM | 96-h | Colon | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | CHO-KI | Ovarian Cancer | MTT assay | IC50=32 µM | 96-h | Ovary | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | HCLO | Colon Cancer | MTT assay | IC50=33.5 µM | 96-h | Colon | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | A-2780 | Ovarian Cancer | MTT assay | IC50=30.6 µM | 96-h | Ovary | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | WEHI-3B | Leukemia Cancer | MTT assay | IC50=4.4 µM | 96-h | Blood | None | ||
| 7849420 | 1994 | Shiva-1 | 38 | Linear | L | None | Free | Free | Antibacterial | Magainin | DLD-1 | Colon Cancer | MTT assay | IC50=>100 µM | 96-h | Colon | None | ||
| 7849420 | 1994 | Shiva-1 | 38 | Linear | L | None | Free | Free | Antibacterial | Magainin | HRT-18 | Colon Cancer | MTT assay | IC50=49.3 µM | 96-h | Colon | None | ||
| 7849420 | 1994 | Shiva-1 | 38 | Linear | L | None | Free | Free | Antibacterial | Magainin | BTS-30 | Breast Cancer | MTT assay | IC50=56 µM | 96-h | Breast | None | ||
| 7849420 | 1994 | Shiva-1 | 38 | Linear | L | None | Free | Free | Antibacterial | Magainin | K-562 | Leukemia Cancer | MTT assay | IC50=28.7 µM | 96-h | Blood | None | ||
| 7849420 | 1994 | Cecropin P1 | 31 | Linear | L | None | Free | Free | Antibacterial | Small Intestine of Pig | DLD-1 | Colon Cancer | MTT assay | IC50=>100 µM | 96-h | Colon | None | ||
| 7849420 | 1994 | Cecropin P1 | 31 | Linear | L | None | Free | Free | Antibacterial | Small Intestine of Pig | HRT-18 | Colon Cancer | MTT assay | IC50=>100 µM | 96-h | Colon | None | ||
| 7849420 | 1994 | Cecropin P1 | 31 | Linear | L | None | Free | Free | Antibacterial | Small Intestine of Pig | BTS-30 | Breast Cancer | MTT assay | IC50=>100 µM | 96-h | Breast | None | ||
| 7849420 | 1994 | Cecropin P1 | 31 | Linear | L | None | Free | Free | Antibacterial | Small Intestine of Pig | K-562 | Leukemia Cancer | MTT assay | IC50=93 µM | 96-h | Blood | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | DLD-1 | Colon Cancer | MTT assay | IC50=>100 µM | 96-h | Colon | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | HRT-18 | Colon Cancer | MTT assay | IC50=25.5 µM | 96-h | Colon | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | BTS-30 | Breast Cancer | MTT assay | IC50=24.8 µM | 96-h | Breast | None | ||
| 7849420 | 1994 | Cecropin B | 35 | Linear | L | None | Amidation | Free | Antibacterial | Hyalophora Cecropia(silkmoth) | K-562 | Leukemia Cancer | MTT assay | IC50=15.5 µM | 96-h | Blood | None | ||
| None | 2019 | IDP-NLCa02 | 35 | Linear | L | None | Free | Free | Anticancer | Synthetic | RG1 | Glioblastoma | AlamarBlue assay | EC50 ~ 5 μM | 72-96 h | Brain | WO 2019/025432 Al | ||
| None | 2020 | IDP-LLCb02 | 33 | Linear | L | None | Free | Free | Anticancer | Synthetic | NCl-H187 | Lung Cancer | MTT/Alamamar-Blue/Hexosaminidase activity test | EC50 ~ 7.5 μM | 48-72 h | Lung | US20200239547A1 | ||
| None | 2020 | IDP-LLCb02 | 33 | Linear | L | None | Free | Free | Anticancer | Synthetic | NCl-H82 | Lung Cancer | MTT/Alamamar-Blue/Hexosaminidase activity test | EC50 ~ 10 μM | 48-72 h | Lung | US20200239547A1 | ||
| None | 2020 | IDP-LLCb02 | 33 | Linear | L | None | Free | Free | Anticancer | Synthetic | NCl-H510A | Lung Cancer | MTT/Alamamar-Blue/Hexosaminidase activity test | EC50 ~ 15 μM | 48-72 h | Lung | US20200239547A1 | ||
| None | 2022 | Sample Peptide 1 from US011339203B2 | 35 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | CAKI-2 | Renal Cancer | CCK-8 assay | Cell Viability = 48% at 25 μM | 48-h | Kidney | US011339203B2 | ||
| None | 2022 | Sample Peptide 2 from US011339203B2 | 35 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | CAKI-2 | Renal Cancer | CCK-8 assay | Cell Viability = 0.4% at 25 μM | 48-h | Kidney | US011339203B2 | ||
| None | 2022 | Sample Peptide 3 from US011339203B2 | 35 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | CAKI-2 | Renal Cancer | CCK-8 assay | Cell Viability = 45.8% at 25 μM | 48-h | Kidney | US011339203B2 | ||
| None | 2022 | Sample Peptide 4 from US011339203B2 | 35 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | CAKI-2 | Renal Cancer | CCK-8 assay | Cell Viability = 85.6% at 25 μM | 48-h | Kidney | US011339203B2 | ||
| None | 2022 | Sample Peptide 6 from US011339203B2 | 34 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | CAKI-2 | Renal Cancer | CCK-8 assay | Cell Viability = 59.7% at 25 μM | 48-h | Kidney | US011339203B2 | ||
| None | 2022 | Sample Peptide 7 from US011339203B2 | 34 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | CAKI-2 | Renal Cancer | CCK-8 assay | Cell Viability = 66.3% at 25 μM | 48-h | Kidney | US011339203B2 | ||
| None | 2022 | Sample Peptide 2 from US011339203B2 | 35 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | PC-3 | Prostate Cancer | CCK-8 assay | Cell Viability = 2.5% at 25 μM | 48-h | Kidney | US011339203B2 | ||
| None | 2022 | Sample Peptide 2 from US011339203B2 | 35 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | A-2058 | Skin Cancer | CCK-8 assay | Cell Viability = 0.2% at 25 μM | 48-h | Skin | US011339203B2 | ||
| None | 2022 | Sample Peptide 2 from US011339203B2 | 35 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | NCI-H2444 | Lung Cancer | CCK-8 assay | Cell Viability = 0.6% at 25 μM | 48-h | Lung | US011339203B2 | ||
| None | 2022 | Sample Peptide 2 from US011339203B2 | 35 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | A-549 | Lung Cancer | CCK-8 assay | Cell Viability = 1.4% at 25 μM | 48-h | Lung | US011339203B2 | ||
| None | 2023 | Sample Peptide 1 from EP3604345B1 | 33 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | NCI-H2444 | Lung Cancer | CCK-8 / WST-8 | Cell Viability = 6.8% at 25 μM | 48-h | Lung | EP3604345B1;US11352408B2 | ||
| None | 2023 | Sample Peptide 3 from EP3604345B1 | 31 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | NCI-H2444 | Lung Cancer | CCK-8 / WST-8 | Cell Viability = 87.7% at 25 μM | 48-h | Lung | EP3604345B1 | ||
| None | 2023 | Sample Peptide 1 from EP3604345B1 | 33 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | HCC-827 | Lung Cancer | CCK-8 / WST-8 | Cell Viability = 11.8% at 25 μM | 48-h | Lung | EP3604345B1 | ||
| None | 2023 | Sample Peptide 3 from EP3604345B1 | 31 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | HCC-827 | Lung Cancer | CCK-8 / WST-8 | Cell Viability = 120.6% at 25 μM | 48-h | Lung | EP3604345B1 | ||
| None | 2023 | Sample Peptide 4 from EP3604345B1 | 33 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | HCC-827 | Lung Cancer | CCK-8 / WST-8 | Cell Viability = 102.6% at 25 μM | 48-h | Lung | EP3604345B1 | ||
| None | 2023 | Sample Peptide 1 from EP3604345B1 | 33 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | NCI-H446 | Lung Cancer | CCK-8 / WST-8 | Cell Viability = 0.5% at 25 μM | 48-h | Lung | EP3604345B1 | ||
| None | 2023 | Sample Peptide 3 from EP3604345B1 | 31 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | NCI-H446 | Lung Cancer | CCK-8 / WST-8 | Cell Viability = 56.7% at 25 μM | 48-h | Lung | EP3604345B1 | ||
| None | 2023 | Sample Peptide 1 from EP3604345B1 | 33 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | A-2058 | Skin Cancer | CCK-8 / WST-8 | Cell Viability = 6.7% at 25 μM | 48-h | Skin | EP3604345B1 | ||
| None | 2023 | Sample Peptide 3 from EP3604345B1 | 31 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | A-2058 | Skin Cancer | CCK-8 / WST-8 | Cell Viability = 87.5% at 25 μM | 48-h | Skin | EP3604345B1 | ||
| None | 2023 | Sample Peptide 1 from EP3604345B1 | 33 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | MDA-MB-231 | Breast Cancer | CCK-8 / WST-8 | Cell Viability = 62.3% at 25 μM | 48-h | Breast | EP3604345B1 | ||
| None | 2023 | Sample Peptide 3 from EP3604345B1 | 31 | Linear | L | None | Amidation | Free | Anticancer | Synthetic | MDA-MB-231 | Breast Cancer | CCK-8 / WST-8 | Cell Viability = 81.7% at 25 μM | 48-h | Breast | EP3604345B1 |