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| ID | PMID | YEAR | Sequence | Name | Length | Linear/Cyclic | Chirality | Chem-MOD | C-ter MOD | N-ter MOD | Nature | Origin | Cell Line | Cancer Type | Assay | Activity | Testing Time | Tissue Affected | Patents |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 37104235 | 2023 | LHRH-BinBC | 195 | Linear | L | None | Free | Fused a luteinizing hormone-releasing hormone (LHRH) peptide | Mosquitocidal, Anticancer | Synthetic | MCF-7 | Breast Cancer | LDH leakage assay | 40% LDH efflux at 16 µM | 48-h | Breast | None | ||
| 37104235 | 2023 | LHRH-BinBC | 195 | Linear | L | None | Free | Fused a luteinizing hormone-releasing hormone (LHRH) peptide | Mosquitocidal, Anticancer | Synthetic | MCF-7 | Breast Cancer | MTT assay | IC50 = 10.96 μM | 48-h | Breast | None | ||
| 33044599 | 2020 | Latcripin-7A | 164 | Linear | L | None | Free | Free | Anticancer | Lentinula edodes | MDA-MB-231 | Breast Cancer | CCK-8 assay | IC50 = 122 μg/mL | 48-h | Breast | None | ||
| 33044599 | 2020 | Latcripin-7A | 164 | Linear | L | None | Free | Free | Anticancer | Lentinula edodes | MCF-7 | Breast Cancer | CCK-8 assay | IC50 = 91 μg/mL | 48-h | Breast | None | ||
| 32069989 | 2020 | Colicin N | 321 | Linear | L | None | Free | Free | Antimicrobial | NA | NCI-H23 | Lung Cancer | MTT assay | Dose dependent % cell viability resuctuction at 1-15 µM | 24-h | Lung | None | ||
| 32069989 | 2020 | Colicin N | 321 | Linear | L | None | Free | Free | Antimicrobial | NA | H-292 | Lung Cancer | MTT assay | Dose dependent % cell viability resuctuction at 1-15 µM | 24-h | Lung | None | ||
| 32069989 | 2020 | Colicin N | 321 | Linear | L | None | Free | Free | Antimicrobial | NA | H-460 | Lung Cancer | MTT assay | Dose dependent % cell viability resuctuction at 1-15 µM | 24-h | Lung | None | ||
| 30013033 | 2018 | Ec-LDP-hBD1 | 198 | Linear | L | None | Free | Free | Antitumor | Synthetic | PG-BE1 | Lung Cancer | CCK-8 assay | IC50 = 31.3 μM | 24-h | Lung | None | ||
| 30013033 | 2018 | Ec-LDP-hBD1 | 198 | Linear | L | None | Free | Free | Antitumor | Synthetic | H-460 | Lung Cancer | CCK-8 assay | IC50 = 5.19 μM | 24-h | Lung | None | ||
| 30013033 | 2018 | Ec-LDP-hBD1 | 198 | Linear | L | None | Free | Free | Antitumor | Synthetic | A-549 | Lung Cancer | CCK-8 assay | IC50 = 11.9 μM | 24-h | Lung | None | ||
| 30013033 | 2018 | Ec-LDP-hBD1 | 198 | Linear | L | None | Free | Free | Antitumor | Synthetic | A-431 | Skin Cancer | CCK-8 assay | IC50 = 1.8 μM | 24-h | Skin | None | ||
| 26519876 | 2016 | BnSP-6 | 133 | Linear | L | None | Free | Free | Antitumor | B. pauloensis | MDA-MB-231 | Breast Cancer | MTT assay | 45% cell cytotoxicity at 100 μg/mL | 24-h | Breast | None | ||
| 23034893 | 2012 | AAD (or Aa-Pri1) | 145 | Linear | L | None | Free | Free | Antitumor | Purified from Agrocybe aegerita | SH-SY5Y | Brain Tumor | MTT/MTS assay | At 2.5 µM concentration,decrease in cell vibility= 70% | 48-h | Brain | None | ||
| 23034893 | 2012 | AAD (or Aa-Pri1) | 145 | Linear | L | None | Free | Free | Antitumor | Purified from Agrocybe aegerita | HeLa | Cervical Cancer | MTT/MTS assay | At 2.5 µM concentration,decrease in cell vibility= 70% | 48-h | Cervix | None | ||
| 23034893 | 2012 | AAD (or Aa-Pri1) | 145 | Linear | L | None | Free | Free | Antitumor | Purified from Agrocybe aegerita | HepG-2 | Liver Cancer | MTT/MTS assay | At 2.5 µM concentration,decrease in cell vibility= 35% | 48-h | Liver | None | ||
| 22963485 | 2012 | RGD-mda-7 | 207 | Linear | L | None | Free | Free | Anticancer | Derived from wtmda-7/IL-24 by insertion og a glycine residue between Arg(164) and Asp(165). | Ket-3 | Tumor | MTT assay | Apoptotic rate(%)= >50% at concentration of 8 µg/ml | 72-h | Not Available | None | ||
| 22963485 | 2012 | RGD-mda-7 | 207 | Linear | L | None | Free | Free | Anticancer | Derived from wtmda-7/IL-24 by insertion og a glycine residue between Arg(164) and Asp(165). | MCF-7 | Breast Cancer | MTT assay | Apoptotic rate(%)= >70% at concentration of 8 µg/ml | 72-h | Breast | None | ||
| 22963485 | 2012 | wtmda-7/IL-24 | 206 | Linear | L | None | Free | Free | Anticancer | NA | Ket-3 | Tumor | MTT assay | Apoptotic rate(%)= >30% at concentration of 8 µg/ml | 72-h | Not Available | None | ||
| 22963485 | 2012 | wtmda-7/IL-24 | 206 | Linear | L | None | Free | Free | Anticancer | NA | MCF-7 | Breast Cancer | MTT assay | Apoptotic rate(%)= >50% at concentration of 8 µg/ml | 72-h | Breast | None | ||
| 22963485 | 2012 | RGD-mda-7 | 207 | Linear | L | None | Free | Free | Anticancer | Derived from wtmda-7/IL-24 by insertion og a glycine residue between Arg(164) and Asp(165). | Ket-3 | Tumor | MTT/MTS assay | Cell viability(% of control)= 0.5 at concentration 8 µg/ml | 48-h | Not Available | None | ||
| 22963485 | 2012 | RGD-mda-7 | 207 | Linear | L | None | Free | Free | Anticancer | Derived from wtmda-7/IL-24 by insertion og a glycine residue between Arg(164) and Asp(165). | MCF-7 | Breast Cancer | MTT/MTS assay | Cell viability(% of control)=0.5 at concentration 4 µg/ml | 48-h | Breast | None | ||
| 22963485 | 2012 | wtmda-7/IL-24 | 206 | Linear | L | None | Free | Free | Anticancer | NA | Ket-3 | Tumor | MTT/MTS assay | Cell viability(% of control)= 0.5 at concentration 8 µg/ml | 48-h | Not Available | None | ||
| 22963485 | 2012 | wtmda-7/IL-24 | 206 | Linear | L | None | Free | Free | Anticancer | NA | MCF-7 | Breast Cancer | MTT/MTS assay | Cell viability(% of control)=0.5 at concentration 7 µg/ml | 48-h | Breast | None | ||
| 26125720 | 2007 | Endostatin | 172 | Linear | L | None | Free | Free | Antiangiogenic | P. pastoris | MFC | Stomach Cancer | IP injections | Tumor inhibition rate = 72.89% | 14 days | Stomach | None |