CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2592
Detailed information
CancerLivER ID2592
Biomarker ITGA6, SPP1
Biomarker Name/Symbol (given in Publication)ITGA6 and SPP1
BiomoleculeRNAs
SubjectHuman
Degree of ValidityPotential progostic marker for Extrahepatic recurrence in HCC; but not validated on indpendent dataset
Experimental ConditionHCC with EHR (Extrahepatic recurrence) v/s HCC without EHR.
Cancer typeHepatocellular carcinoma
RegulationUpregulated in HCC with EHR than HCC without EHR and non-cancerous liver tissue ( also higher expression in HCC without EHR than non-cancerous liver tissue)
Level of significance P< 0.05
SourceTissue
PMID17016605
Type of BiomarkerPrognostic
PathwayCell adhesion
Cohort76 HCC samples : 35 HCC for recurrence (5 had extrahepatic metastases at surgery, and 5 had EHR after curative surgery. These 10 patients were classified as the EHR group. The remaining 25 patients, who had no EHR during the follow-up period, were classified as the non-EHR group).
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHCC with EHR (Extrahepatic recurrence) v/s HCC without EHR.
Year of Publication2006
Clinical trialNO
Clinical trial (NCT Number)NA

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