Detailed information |
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CancerLivER ID | 2579 |
Biomarker | HSPA1B |
Biomarker Name/Symbol (given in Publication) | HSPA1B |
Biomolecule | RNAs |
Subject | Human |
Degree of Validity | Potential diagnostic marker for HBV-HCCs patients with LC (liver cirrhosis); but not validated on independent datase |
Experimental Condition | HBV-HCCs patients with LC (liver cirrhosis) vs without LC (liver cirrhosis) |
Cancer type | Hepatocellular carcinoma |
Regulation | Downregulated in HBV-HCCs from patients with LC than HBV-HCCs without LC |
Level of significance | P< 0.05 |
Source | Tissue |
PMID | 12771952 |
Type of Biomarker | Diagnostic |
Pathway | cell-growth |
Cohort | 45 hepatocellular carcinoma (HCC) samples, we evaluated gene expression in hepatitis B virus-positive and hepatitis C virus-positive HCCs (HBV- and HCV-HCCs) for an association with liver cirrhosis (LC). 14 HBV- and 31 HCV-HCC patients among 14 HBV- HCC patients, eight had pathological LC, and the r |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | (HBV- and HCV-HCCs), HBV-HCCs associated with LC and those not associated with LC. |
Year of Publication | 2003 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |