CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2573
Detailed information
CancerLivER ID2573
Biomarker BMP4, FLNB, GNG11, GFR, and PTPRK
Biomarker Name/Symbol (given in Publication)BMP4, FLNB, GNG11, GFR, and PTPRK
BiomoleculeRNAs
SubjectHuman
Degree of ValidityPotential diagnostic marker for HBV-HCCs patients with LC (liver cirrhosis); but not validated on independent datase
Experimental ConditionHBV-HCCs patients with LC (liver cirrhosis) vs without LC (liver cirrhosis)
Cancer typeHepatocellular carcinoma
RegulationUpregulated in HBV-HCCs from patients with LC
Level of significance P< 0.05
SourceTissue
PMID12771952
Type of BiomarkerDiagnostic
Pathwaysignal transduction
Cohort45 hepatocellular carcinoma (HCC) samples, we evaluated gene expression in hepatitis B virus-positive and hepatitis C virus-positive HCCs (HBV- and HCV-HCCs) for an association with liver cirrhosis (LC). 14 HBV- and 31 HCV-HCC patients among 14 HBV- HCC patients, eight had pathological LC, and the r
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
Disease(HBV- and HCV-HCCs), HBV-HCCs associated with LC and those not associated with LC.
Year of Publication2003
Clinical trialNO
Clinical trial (NCT Number)NA

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