Detailed information |
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CancerLivER ID | 2568 |
Biomarker | VIM or Vimentin |
Biomarker Name/Symbol (given in Publication) | VIM or Vimentin |
Biomolecule | RNAs |
Subject | Human |
Degree of Validity | Potential prognostic marker for HCC metastasis; but not validated on independent dataset |
Experimental Condition | Primary v/s metastasis; significantly associated with HCC metastasis |
Cancer type | Hepatocellular carcinoma |
Regulation | Upegulated in HCC |
Level of significance | p< 0.01 |
Source | Tissue |
PMID | 14647434 |
Type of Biomarker | Prognostic |
Pathway | Adhesion, cell motility and invasiveness, ECM signaling,classical complement activation pathway |
Cohort | 200 primary HCCs and 60 pairs of primary and matched metastatic HCC samples ((including 31 intrahepatic and 29 extrahepatic metastases). |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | HCC |
Year of Publication | 2003 |
Clinical trial | YES |
NCT No# (Clinical trial) | NCT00987766 |