| Detailed information |
|---|
| CancerLivER ID | 2561 |
| Biomarker | HSP70 |
| Biomarker Name/Symbol (given in Publication) | heat-shock protein 70 (HSP70). |
| Biomolecule | Protein |
| Subject | Human |
| Degree of Validity | HSP70 could be a sensitive marker for the differential diagnosis of early HCC from precancerous lesion or noncancerous liver and validated on independent dataset |
| Experimental Condition | nodule-in-nodule-type HCCs and corresponding noncancerous liver tissues |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Upregulated in early HCC components |
| Level of significance | p< .001 |
| Source | Tissue |
| PMID | 12500205 |
| Type of Biomarker | Diagnostic and prognostic |
| Pathway | Chaperone |
| Cohort | 7 pairs of nodule-in-nodule-type HCCs (progressed HCC within early HCC) represents the transition from early to progressed HCC ) and corresponding noncancerous liver tissues. Serologically, 1 case was positive for hepatitis-B-surface-antigen, 5 cases were hepatitis C virus (HCV)-positive, and 1 was |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | nodule-in-nodule-type HCCs and corresponding noncancerous liver tissues |
| Year of Publication | 2003 |
| Clinical trial | YES |
| NCT No# (Clinical trial) | NCT00769535 |