CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2554
Detailed information
CancerLivER ID2554
Biomarker sterol-C5-desaturase, Peroxisomal phytanoyl-CoA alpha-hydroxylase, Homo sapiens clone 23915, Osteopontin 5/6 0, Full-length cDNA clone ZD66D02, Senescence-associated epithelial membrane protein(SEMP1), Human DNA topoisomerase II (top2) mRNA, Homo sapiens lysosomal membrane glycoprotein-2 (LAMP2), Hu
Biomarker Name/Symbol (given in Publication)sterol-C5-desaturase, Peroxisomal phytanoyl-CoA alpha-hydroxylase, Homo sapiens clone 23915, Osteopontin, Full-length cDNA clone ZD66D02, Senescence-associated epithelial membrane protein(SEMP1), Human DNA topoisomerase II (top2) mRNA, Homo sapiens lysosomal membrane glycoprotein-2 (LAMP2), Human farnesyl pyrophosphate synthetase mRNA, Human syndecan mRNA, Human prealbumin mRNA, Cystathionine beta-synthase subunit (CBS), Paraoxonase 2 (PON2), Human prealbumin mRNA, Chondroitin/dermatan sulfate proteoglycan(PG40) core protein, Human chondroitin/dermatan sulfate proteoglycan (PG40) core protein mRNA, Human cytochrome P-450 1 functional form mRNA, Human cytochrome P-450 1 mRNA, Cytochrome b5, Human B61 mRNA, Human sterol 27-hydroxylase (CYP27) mRNA, Glycine decarboxylase, Human sterol carrier protein X/sterol carrier protein 2 mRNA, Dihydrodiol dehydrogenase, Dihydrodiol dehydrogenase, Guanine nucleotide exchange factor p532, Fumarase precursor (FH), Human mRNA for fibronectin (FN precursor), Human kidney mRNA for catalase, Inter-alpha-trypsin inhibitor complex, second protein, Osteopontin, H.sapiens mRNA for mitochondrial phosphate carrier protein, Propionyl-CoA carboxylase a subunit, L-arginine:glycine amidinotransferase, Translational inhibitor protein p14.5, Complement factor H, Human mRNA for complement factor H, Phenylalkylamine binding protein
BiomoleculeRNAs
SubjectHuman
Degree of ValidityPotential diagnostic marker for HCC; but not validated on independent dataset
Experimental ConditionTumor v/s normal
Cancer typeHepatocellular carcinoma
RegulationUpregulated in HCC than non-tumor
Level of significance NA
SourceTissue
PMID12136251
Type of BiomarkerDiagnostic
PathwayCell growth and differentiation, metastasis, the function of the immune system, apoptosis, and remodeling of the cytoskeleton.
CohortCancerous liver tissue from 11 patients diagnosed with primary hepatocellular carcinoma and one with hepatic schistosomiasis were excised from patients and Liver tissues of two healthy individuals
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseLiver cancer
Year of Publication2002
Clinical trialNO
Clinical trial (NCT Number)NA

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