CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2553
Detailed information
CancerLivER ID2553
Biomarker Keratin type I cytoskeletal 10, Catalase, Aldehyde dehydrogenase (mitochondrial), GlutathioneS-transferase A1, Antioxidant protein 2, Isocitrate dehydrogenase [NADP] (cytoplasmic), Formiminotransferase-cyclodeaminase, Carbonic anhydrase I, Fructose bisphosphate aldolase B, Arginase 1, Fructose-1, 6-
Biomarker Name/Symbol (given in Publication)Keratin type I cytoskeletal 10, Catalase, Aldehyde dehydrogenase (mitochondrial), GlutathioneS-transferase A1, Antioxidant protein 2, Isocitrate dehydrogenase [NADP] (cytoplasmic), Formiminotransferase-cyclodeaminase, Carbonic anhydrase I, Fructose bisphosphate aldolase B, Arginase 1, Fructose-1, 6-bisphosphatase, C-1-tetrahydrofolate synthase (cytoplasmic), Electron transfer flavoprotein alpha-subunit (mitochondrial), Alcohol dehydrogenase [NADP1], Acyl-CoA dehydrogenase (mitochondrial), Fumarylacetoacetase, Glycerol-3-phosphate dehydrogenase[NAD1] (cytoplasmic), Adenosylhomocysteinase, Acetyl-CoA acetyltransferase (mitochondrial), Flavin reductase, Enoyl-CoA hydratase (mitochondrial), 4-Hydroxyphenylpyruvatedioxygenase, Acyl-CoA dehydrogenase (mitochondrial), Ketohexokinase, Glycine amidinotransferase (mitochondrial), S-adenosylmethionine synthase, Delta 3,5-delta2, 4-dienoyl-CoAisomerase (mitochondrial), Aminocyclase-1, Glycine N-methyltransferase, Beta-ureidopropionase, Betaine-homocysteineS-methyl-transferase, Homogentisate 1,2-dioxygenase, Elongation factor Tu (mitochondrial), Senescence marker protein-30, Phosphatidylethanolamine-binding protein, Nonspecific lipid-transfer protein (mitochondrial), Serotransferrin precursor, Pyridoxine 5-phosphate oxidase, Unnamed protein product, MAWD binding protein
BiomoleculeProtein
SubjectHuman
Degree of ValidityPotential diagnostic marker for HCC; but not validated on independent dataset
Experimental ConditionHCC v/s non-tumor
Cancer typeHepatocellular carcinoma
RegulationDownregulated in poorly-differentiated HCC (with 2 fold change)
Level of significance p < 0.05
SourceTissue
PMID15852300
Type of BiomarkerDiagnostic
Pathwaycytoskeltal related pathways, metabolic pathways, detoxification, Transport and binding protein
CohortPaired HCC and non-tumorous from 7 HCC patients
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHBV-associated HCC
Year of Publication2005
Clinical trialNO
Clinical trial (NCT Number)NA

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