CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2539
Detailed information
CancerLivER ID2539
Biomarker NRCAM, CD24, CTHRC1, ROBO1, CENPM, FOXQ1, CDCA7L, MYBL2, PAFAH1B3, STK39, SPINK1, AKR1B10, SLC6A8, SOX4,
Biomarker Name/Symbol (given in Publication)NRCAM, CD24, CTHRC1, ROBO1, CENPM, FOXQ1, CDCA7-L, MYBL2, PAFAH1B3, STK39, SPINK1, AKR1B10, SLC6A8 and SOX4
BiomoleculeRNAs
SubjectHuman
Degree of ValidityPotential pathological staging marker of HCC and upregulated in T3 than T1 and adjacent non-tumor (with 6 fold change); but not validated on independent dataset
Experimental ConditionIntrahepatic metastasis v/s primary HCC and normal
Cancer typeHepatocellular carcinoma
RegulationUpregulated in T3 than T1 and adjacent non-tumor (with 6 fold change)
Level of significance p < 0.05
SourceTissue
PMID18504433
Type of BiomarkerPrognostic
PathwayAdhesion molecules and Transcription factor
CohortTraining dataset: 4 primary HCC (T1), 6 intrahepatic metastatic HCC (T3) and 2 normal liver samples (HNL); validation dataset : T3 tumors (n=24) /higher than adjacent normal tissues (n=61, adjacent-average) and T1 tumors (n=15).
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseIntrahepatic metastasis v/s primary HCC and normal
Year of Publication2008
Clinical trialNO
Clinical trial (NCT Number)NA

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