CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2521
Detailed information
CancerLivER ID2521
BiomarkerGain of Chromosome 7
Biomarker Name/Symbol (given in Publication)Gain of Chromosome 7
BiomoleculeCopy Number variation
SubjectHuman
Degree of Validitylow-level gains of chromosome 7 were independent predictors of overall recurrence; but not validated on independent dataset
Experimental ConditionEarly recurrence v/s late recurrence
Cancer typeHepatocellular carcinoma
RegulationChromosome 7 median copy number > 2.2 associated with overall recurrence in HCC (with Hazard ratio 3.4)
Level of significance p < 0.001
SourceTissue
PMID18701503
Type of BiomarkerPrognostic
PathwayNA
CohortTotal 103 tumor samples from 100 patients used in study; Clinical recurrence studied in 82 patients
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseEarly recurrence HCC v/s Late recurrence
Year of Publication2008
Clinical trialNO
Clinical trial (NCT Number)NA

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