| Detailed information |
|---|
| CancerLivER ID | 2520 |
| Biomarker | Gain of Chromosome 7 |
| Biomarker Name/Symbol (given in Publication) | Gain of Chromosome 7 |
| Biomolecule | Copy Number variation |
| Subject | Human |
| Degree of Validity | low-level gains of chromosome 7 were independent predictors of recurrence within 2 years of surgical resection; but not validated on independent dataset |
| Experimental Condition | Early recurrence v/s late recurrence |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Chromosome 7 median copy number > 2.2 associated with early recurrence (within 2 years) in HCC (with Hazard ratio 5.8) |
| Level of significance | p < 0.001 |
| Source | Tissue |
| PMID | 18701503 |
| Type of Biomarker | Prognostic |
| Pathway | NA |
| Cohort | Total 103 tumor samples from 100 patients used in study; Clinical recurrence studied in 82 patients |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | Early recurrence HCC v/s Late recurrence |
| Year of Publication | 2008 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |