| Detailed information |
|---|
| CancerLivER ID | 2364 |
| Biomarker | UBE4B |
| Biomarker Name/Symbol (given in Publication) | UBE4B |
| Biomolecule | RNAs |
| Subject | Human cell line |
| Degree of Validity | UBE4B could represent a candidate drug-resistant gene; but not validated on human patient cohort |
| Experimental Condition | IFN-α treatment tolerant v/s non tolerant cells |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Downregulated in IFN-alpha drug-tolerant cells |
| Level of significance | FDR <0.5%. |
| Source | Cell line |
| PMID | 15709204 |
| Type of Biomarker | Potential Predictive * |
| Pathway | Catalyzes ubiquitin chain assembly and protein degradation |
| Cohort | Human HCC cell lines (HKCI-1, HKCI-2, HKCI-3, HKCI-4, HKCI-C1, HKCI-C2, and HKCI-C3) |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | IFN-α treatment tolerant v/s non tolerant cells of HCV associated HCC |
| Year of Publication | 2005 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |