Detailed information |
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CancerLivER ID | 2362 |
Biomarker | ZNF185 |
Biomarker Name/Symbol (given in Publication) | ZNF185 |
Biomolecule | RNAs |
Subject | Human cell line |
Degree of Validity | Potential candidate genes in conferring an anti-apoptotic effect toward IFN-alpha treatment; but not validated on human patient cohort |
Experimental Condition | IFN-α treatment tolerant v/s non tolerant cells |
Cancer type | Hepatocellular carcinoma |
Regulation | Upregulated in IFN-alpha drug-tolerant cells |
Level of significance | FDR <0.5%. |
Source | Cell line |
PMID | 15709204 |
Type of Biomarker | Potential Predictive * |
Pathway | cellular proliferation and differentiation |
Cohort | Human HCC cell lines (HKCI-1, HKCI-2, HKCI-3, HKCI-4, HKCI-C1, HKCI-C2, and HKCI-C3) |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | IFN-α treatment tolerant v/s non tolerant cells of HCV associated HCC |
Year of Publication | 2005 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |