CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2362
Detailed information
CancerLivER ID2362
Biomarker ZNF185
Biomarker Name/Symbol (given in Publication)ZNF185
BiomoleculeRNAs
SubjectHuman cell line
Degree of ValidityPotential candidate genes in conferring an anti-apoptotic effect toward IFN-alpha treatment; but not validated on human patient cohort
Experimental ConditionIFN-α treatment tolerant v/s non tolerant cells
Cancer typeHepatocellular carcinoma
RegulationUpregulated in IFN-alpha drug-tolerant cells
Level of significance FDR <0.5%.
SourceCell line
PMID15709204
Type of BiomarkerPotential Predictive *
Pathwaycellular proliferation and differentiation
CohortHuman HCC cell lines (HKCI-1, HKCI-2, HKCI-3, HKCI-4, HKCI-C1, HKCI-C2, and HKCI-C3)
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
Disease IFN-α treatment tolerant v/s non tolerant cells of HCV associated HCC
Year of Publication2005
Clinical trialNO
Clinical trial (NCT Number)NA

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