CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2317
Detailed information
CancerLivER ID2317
Biomarker NDRG2
Biomarker Name/Symbol (given in Publication)NDRG2
BiomoleculeProtein and RNAs
SubjectHuman
Degree of ValidityPotential biomarker for HCC prognosis and diagnosis; NDRG2 might be a novel candidate suppressor of tumor metastasis in HCC; but not validated on independent dataset
Experimental ConditionHCC v/s cirrhosis/healthy/non-tumor HCC; associated with recurrence and tumor grade
Cancer typeHepatocellular carcinoma
RegulationDownregulated in HCC than non-tumor
Level of significance p < 0.05
SourceTissue
PMID18519680
Type of BiomarkerDiagnostic and Prognostic
Pathwaydendritic cell and neuron differentiation
Cohort57 tumor and 41 nontumor liver tissues of HCC patients; iver cancer cell lines, PLC/PRF/5 and SK-Hep-1,
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHCC v/s non-tumor HCC
Year of Publication2008
Clinical trialNO
Clinical trial (NCT Number)NA

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