Detailed information |
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CancerLivER ID | 2317 |
Biomarker | NDRG2 |
Biomarker Name/Symbol (given in Publication) | NDRG2 |
Biomolecule | Protein and RNAs |
Subject | Human |
Degree of Validity | Potential biomarker for HCC prognosis and diagnosis; NDRG2 might be a novel candidate suppressor of tumor metastasis in HCC; but not validated on independent dataset |
Experimental Condition | HCC v/s cirrhosis/healthy/non-tumor HCC; associated with recurrence and tumor grade |
Cancer type | Hepatocellular carcinoma |
Regulation | Downregulated in HCC than non-tumor |
Level of significance | p < 0.05 |
Source | Tissue |
PMID | 18519680 |
Type of Biomarker | Diagnostic and Prognostic |
Pathway | dendritic cell and neuron differentiation |
Cohort | 57 tumor and 41 nontumor liver tissues of HCC patients; iver cancer cell lines, PLC/PRF/5 and SK-Hep-1, |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | HCC v/s non-tumor HCC |
Year of Publication | 2008 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |