CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2308
Detailed information
CancerLivER ID2308
Biomarker ASPM
Biomarker Name/Symbol (given in Publication)ASPM
BiomoleculeRNAs
SubjectHuman
Degree of ValidityPotential marker for cirrhosis; but not validated on independent dataset
Experimental Conditiondysplasia v/s early/late HCC and normal
Cancer typeHepatocellular carcinoma
RegulationUpregulated in early/advanced HCC v/s control and dysplasia
Level of significance p < 0.05
SourceTissue
PMID17393520
Type of BiomarkerDiagnostic
Pathwaynormal mitotic spindle function
Cohort75 samples (48 patients): Sixty-five samples were obtained from 38 patients with HCV infection representing 13 samples from cirrhotic tissue, 17 dysplastic nodules, and 35 HCCs; samples of normal tissue obtained from the healthy livers of 10 patients undergoing resection for hepatic hemangioma (1),
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
Diseasedysplasia v/s early/late HCC and normal
Year of Publication2007
Clinical trialNO
Clinical trial (NCT Number)NA

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