CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2302
Detailed information
CancerLivER ID2302
Biomarker CD58
Biomarker Name/Symbol (given in Publication)CD58
BiomoleculeRNAs
SubjectHuman
Degree of ValidityPotential diagnostic marker for HBV associated HCC; but not validated on independent dataset
Experimental ConditionHCV associated HCC v/s normal and HBV associated HCC
Cancer typeHepatocellular carcinoma
RegulationUpregulated in HCV associated HCC (v/s normal samples with fold change 4.68) and (ratio of HBV-HCC v/s HCV-HCC 0.31)
Level of significance p < 0.05
SourceTissue
PMID18932288
Type of BiomarkerDiagnostic
Pathwaycell adhesion
Cohort32 pairs of specimens (tumorous and surrounding non-tumorous liver tissues): 15 lymph node negative and 17 lymph node positive cases or HBV- associated HCC group in which HBV was positive in 17 patients, and HCV-associated HCC group in which HCV was positive in 15 patients
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHCV associated HCC v/s normal and HBV associated HCC
Year of Publication2008
Clinical trialNO
Clinical trial (NCT Number)NA

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