CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2298
Detailed information
CancerLivER ID2298
Biomarker MMP9
Biomarker Name/Symbol (given in Publication)MMP9
BiomoleculeRNAs
SubjectHuman
Degree of ValidityPotential diagnostic marker for HBV associated HCC; but not validated on independent dataset
Experimental ConditionHBV associated HCC v/s normal and HCV associated HCC
Cancer typeHepatocellular carcinoma
RegulationUpregulated in HBV associated HCC (v/s normal samples with fold change 7.43) and (v/s HCV associated HCC with ratio of 3.74)
Level of significance p < 0.05
SourceTissue
PMID18932288
Type of BiomarkerDiagnostic
Pathwaymetastasis-related genes
Cohort32 pairs of specimens (tumorous and surrounding non-tumorous liver tissues): 15 lymph node negative and 17 lymph node positive cases or HBV- associated HCC group in which HBV was positive in 17 patients, and HCV-associated HCC group in which HCV was positive in 15 patients
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHBV associated HCC v/s normal and HCV associated HCC
Year of Publication2008
Clinical trialYES
NCT No# (Clinical trial) NCT03131778,NCT03841201,NCT03753659

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