| Detailed information |
|---|
| CancerLivER ID | 2298 |
| Biomarker | MMP9 |
| Biomarker Name/Symbol (given in Publication) | MMP9 |
| Biomolecule | RNAs |
| Subject | Human |
| Degree of Validity | Potential diagnostic marker for HBV associated HCC; but not validated on independent dataset |
| Experimental Condition | HBV associated HCC v/s normal and HCV associated HCC |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Upregulated in HBV associated HCC (v/s normal samples with fold change 7.43) and (v/s HCV associated HCC with ratio of 3.74) |
| Level of significance | p < 0.05 |
| Source | Tissue |
| PMID | 18932288 |
| Type of Biomarker | Diagnostic |
| Pathway | metastasis-related genes |
| Cohort | 32 pairs of specimens (tumorous and surrounding non-tumorous liver tissues): 15 lymph node negative and 17 lymph node positive cases or HBV- associated HCC group in which HBV was positive in 17 patients, and HCV-associated HCC group in which HCV was positive in 15 patients |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | HBV associated HCC v/s normal and HCV associated HCC |
| Year of Publication | 2008 |
| Clinical trial | YES |
| NCT No# (Clinical trial) | NCT03131778,NCT03841201,NCT03753659 |