CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2270
Detailed information
CancerLivER ID2270
Biomarker IFP53/Tryptophanyl-Trna synthetase
Biomarker Name/Symbol (given in Publication)IFP53/Tryptophanyl-Trna synthetase
BiomoleculeProtein
SubjectHuman
Degree of ValiditySignificantly associated with early intrahepatic recurrence of HCC and validated on independent dataset
Experimental ConditionEarly recurrence v/s No recurrence HCC
Cancer typeHepatocellular carcinoma
RegulationDownregulated in recurrence HCC than non-recurrence HCC (with fold change 0.27)
Level of significance p < 0.05
SourceTissue
PMID17391314
Type of BiomarkerPrognostic
PathwayDNA/RNA synthesis
CohortTraining dataset: 12 early recurrence and 15 no recurrence patients; validation dataset :6 early recurrence and 7 no recurrence patients
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseEarly recurrence v/s No recurrence HCC
Year of Publication2007
Clinical trialNO
Clinical trial (NCT Number)NA

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