CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2256
Detailed information
CancerLivER ID2256
Biomarker Tropomyosin-beta-chain
Biomarker Name/Symbol (given in Publication)Tropomyosin-beta-chain
BiomoleculeProtein
SubjectHuman
Degree of ValidityPotential diagnostic marker; but not valifdated on independent dataset
Experimental ConditionHCC v/s non-tumor
Cancer typeHepatocellular carcinoma
RegulationDownregulated in HCC than non-tumor
Level of significance p < 0.01
SourceTissue
PMID15221772
Type of BiomarkerDiagnostic
PathwayMuscle contraction and regulate ATPase activity
CohortPaired tumor and non-tumor tissue samples form 20 HCC patients [Four patient's HCCs were well differen-tiated, 15 were moderately differentiated, and the last onewas poorly differentiated. Twelve out of the 20 nontumor-ous tissues indicated cirrhotic liver]
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHCV-associated HCC
Year of Publication2004
Clinical trialNO
Clinical trial (NCT Number)NA

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