Detailed information |
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CancerLivER ID | 2256 |
Biomarker | Tropomyosin-beta-chain |
Biomarker Name/Symbol (given in Publication) | Tropomyosin-beta-chain |
Biomolecule | Protein |
Subject | Human |
Degree of Validity | Potential diagnostic marker; but not valifdated on independent dataset |
Experimental Condition | HCC v/s non-tumor |
Cancer type | Hepatocellular carcinoma |
Regulation | Downregulated in HCC than non-tumor |
Level of significance | p < 0.01 |
Source | Tissue |
PMID | 15221772 |
Type of Biomarker | Diagnostic |
Pathway | Muscle contraction and regulate ATPase activity |
Cohort | Paired tumor and non-tumor tissue samples form 20 HCC patients [Four patient's HCCs were well differen-tiated, 15 were moderately differentiated, and the last onewas poorly differentiated. Twelve out of the 20 nontumor-ous tissues indicated cirrhotic liver] |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | HCV-associated HCC |
Year of Publication | 2004 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |