CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2251
Detailed information
CancerLivER ID2251
Biomarker CXCL10
Biomarker Name/Symbol (given in Publication)IFN-gamma inducible protein of 10 kDa or CXCL10
BiomoleculeRNAs
SubjectHuman
Degree of ValidityDifferentially expressed gene
Experimental ConditionHCC v/s CHC and normal
Cancer typeHepatocellular carcinoma
RegulationUpregulated in HCC than CHC and normal (with nearly 13 fold change)
Level of significance p < 0.01
SourceTissue
PMID11401510
Type of BiomarkerDiagnostic
PathwayImmune associated pathways: IFN-inducible genes
CohortTraining dataset: Samples separately obtained from the tumor (diagnosed as well differentiated HCC) and noncancerous liver (diagnosed as chronic active hepatitis); Validation Dataset: 4 HCC tissues from 4 patients, noncancerous background liver tissues from the same patients, and 3 unrelated normal
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHCC and CHC (Chronic hepatitis C)
Year of Publication2001
Clinical trialNO
Clinical trial (NCT Number)NA

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