Detailed information |
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CancerLivER ID | 2246 |
Biomarker | HLA-C |
Biomarker Name/Symbol (given in Publication) | MHC class I C or HLA-C |
Biomolecule | RNAs |
Subject | Human |
Degree of Validity | Differentially expressed gene |
Experimental Condition | HCC and CHC v/s normal |
Cancer type | Hepatocellular carcinoma |
Regulation | Upregulated in HCC and CHC v/s normal (with 67 fold change) |
Level of significance | p < 0.01 |
Source | Tissue |
PMID | 11401510 |
Type of Biomarker | Diagnostic |
Pathway | Immune associated pathways: antigen presentation and processing |
Cohort | Training dataset:Samples separately obtained from the tumor (diagnosed as well differentiated HCC) and noncancerous liver (diagnosed as chronic active hepatitis); Validation Dataset: 4 HCC tissues from 4 patients, noncancerous background liver tissues from the same patients, and 3 unrelated normal l |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | HCC and CHC (Chronic hepatitis C) |
Year of Publication | 2001 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |