| Detailed information |
|---|
| CancerLivER ID | 2236 |
| Biomarker | MALAT1 |
| Biomarker Name/Symbol (given in Publication) | MALAT1 |
| Biomolecule | LncRNA |
| Subject | Human, Mice and cell lines |
| Degree of Validity | lncRNA MALAT1 acts as a proto-oncogene in HCC; but not validated on independent dataset |
| Experimental Condition | HCC v/s Normal |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Upregulated in HCC with Fold change=3.233 |
| Level of significance | p < 0.05 |
| Source | Tissue |
| PMID | 27993818 |
| Type of Biomarker | Diagnostic |
| Pathway | NA |
| Cohort | Normal liver (n=10) and hepatocellular carcinoma (n=35) samples;5 adjacent inflamed liver parenchyma and 20 tumor liver samples from Mdr2 - mice; Liver progenitor cells from embryonic day 18 fetal livers from TP53-mice were isolated and immortalized with MSCV-based retroviruses expressing MYC-IRES-G |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | Human HCC |
| Year of Publication | 2017 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |