Detailed information |
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CancerLivER ID | 2218 |
Biomarker | MYC |
Biomarker Name/Symbol (given in Publication) | MYC |
Biomolecule | Protein |
Subject | Human |
Degree of Validity | Diagnostic or therapeutic biomarkers associated with HCC and validated on independent dataset |
Experimental Condition | HCV-associated HCC v/s healthy/non-tumor/cirrhosis |
Cancer type | Hepatocellular carcinoma |
Regulation | Downregulated in HCC |
Level of significance | p < 0.0001 |
Source | Tissue |
PMID | 28947976 |
Type of Biomarker | Diagnostic |
Pathway | ErbB, VEGF and MAPK signaling pathways |
Cohort | GSE25097 dataset contain 557 samples, including 6 healthy livers, 40 cirrhotic tissue samples, 243 adjacent non-tumor samples, and 268 early-to-advanced stage HCC samples; GSE6764 dataset contains a total of 75 tissue samples, including 10 healthy liver samples, 13 cirrhosis samples, 17 dysplastic |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | Human HCC |
Year of Publication | 2017 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |