CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2212
Detailed information
CancerLivER ID2212
Biomarker KDM6B
Biomarker Name/Symbol (given in Publication)KDM6B
BiomoleculeProtein
SubjectHuman
Degree of ValidityDiagnostic or therapeutic biomarkers associated with HCC and validated on independent dataset
Experimental ConditionHBV-associated HCC v/s healthy/non-tumor/cirrhosis
Cancer typeHepatocellular carcinoma
RegulationDownregulated in HCC
Level of significance p < 0.0001
SourceTissue
PMID28947976
Type of BiomarkerDiagnostic
PathwayErbB, VEGF and MAPK signaling pathways
CohortGSE25097 dataset contain 557 samples, including 6 healthy livers, 40 cirrhotic tissue samples, 243 adjacent non-tumor samples, and 268 early-to-advanced stage HCC samples; GSE6764 dataset contains a total of 75 tissue samples, including 10 healthy liver samples, 13 cirrhosis samples, 17 dysplastic
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHuman HCC
Year of Publication2017
Clinical trialNO
Clinical trial (NCT Number)NA

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