CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2187
Detailed information
CancerLivER ID2187
Biomarker miR-106b-3p, miR-1246
Biomarker Name/Symbol (given in Publication)miR-106b-3p + miR-1246
BiomoleculemiRNA
SubjectHuman
Degree of ValidityPotential diagnostic marker for HCC and validated on independent dataset
Experimental ConditionHCC v/s Cirrhosis
Cancer typeHepatocellular carcinoma
RegulationUpregulated in HCC
Level of significance p < 0.001
SourcePlasma
PMID29632649
Type of BiomarkerDiagnostic
Pathwaycancer- associated processes
Cohort62 clinically diagnosed HCC patients, 41 patients with liver cirrhosis and 25 healthy controls (not affected by liver diseases or any neoplastic disorder) from various Institutions, between April 2012 and November 2015.
Sensitivity87.5
Specificity91.7
Accuracy89.3
AUC0.98
DiseaseHuman HCC, Cirrhosis
Year of Publication2018
Clinical trialNO
Clinical trial (NCT Number)NA

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