| Detailed information |
|---|
| CancerLivER ID | 2172 |
| Biomarker | SOS1 |
| Biomarker Name/Symbol (given in Publication) | SOS1 |
| Biomolecule | RNAs |
| Subject | Human cell lines |
| Degree of Validity | Potential biomarker for hepatocellular carcinoma therapy; but not validated on human patients cohort |
| Experimental Condition | Normal vs hepatoma cells treated with emodin |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Upregulated in hepatoma cell |
| Level of significance | p < 0.0001 |
| Source | Cells |
| PMID | 19895793 |
| Type of Biomarker | Potential Predictive * |
| Pathway | metalloproteinases pathway, anti-tumor pathway of emodin. |
| Cohort | Human hepatoma cell lines (Huh7, Hep3B, and HepG2) were obtained from the Bioresource Collection and Re- search Center (BCRC, Taiwan) |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | Human HCC |
| Year of Publication | 2010 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |