| Detailed information |
|---|
| CancerLivER ID | 2167 |
| Biomarker | CORO1C |
| Biomarker Name/Symbol (given in Publication) | Coronin-1C |
| Biomolecule | Protein |
| Subject | Human |
| Degree of Validity | Coronin-1C could be a candidate biomarker to predict HCC invasive behavior and validated on independent dataset |
| Experimental Condition | Agressive or advanced-stage HCC v/s less-aggressive HCC; predict metastatic stage |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Upregulated in liver cancer tissues of HCCLM9-nude mice with spontaneous pulmonary metastasis and higher coronin-1C expression had more advanced stage in patients |
| Level of significance | p < 0.05 |
| Source | Tissue and Cells |
| PMID | 20181269 |
| Type of Biomarker | Prognostic |
| Pathway | Cell chemotaxis, cytokinesis, phagocytosis, locomotion and migration |
| Cohort | Two cloned cell lines: MHCC97L and HCCLM9 cells; mouse model; 115 HCC patients |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | Human HCC |
| Year of Publication | 2010 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |