CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2163
Detailed information
CancerLivER ID2163
Biomarker miR-525-3p
Biomarker Name/Symbol (given in Publication)miR-525-3p
BiomoleculemiRNA
SubjectHuman
Degree of ValidityPredictor of poor prognosis and validated on independent dataset
Experimental ConditionHCC v/s other liver disease (cirrhosis/dysplasia); predict survival and recurrence of patients
Cancer typeHepatocellular carcinoma
RegulationUpregulated in HCC
Level of significance p < 0.01
SourceTissue
PMID22429613
Type of BiomarkerPrognostic
PathwayTGF-b and WNT signals
CohortThe training cohort: 60 patients serologically positive for HCV infection: (i) 10 end-stage cirrhosis (ii) 10 cirrhosis associated with HCC samples at a distance of at least 3 cm; (iii) 5 low-grade dysplastic nodules; (iv) 5 high-grade dysplastic nodules; (v) 10 early HCCs and (vi) 20 progressed HCC
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHuman HCC
Year of Publication2012
Clinical trialNO
Clinical trial (NCT Number)NA

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