Detailed information |
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CancerLivER ID | 2161 |
Biomarker | miR-518a-3p |
Biomarker Name/Symbol (given in Publication) | miR-518a-3p |
Biomolecule | miRNA |
Subject | Human |
Degree of Validity | Predictor of poor prognosis and validated on independent dataset |
Experimental Condition | HCC v/s other liver disease (cirrhosis/dysplasia); predict survival and recurrence of patients |
Cancer type | Hepatocellular carcinoma |
Regulation | Upregulated in HCC |
Level of significance | p < 0.01 |
Source | Tissue |
PMID | 22429613 |
Type of Biomarker | Prognostic |
Pathway | TGF-b and WNT signals |
Cohort | The training cohort: 60 patients serologically positive for HCV infection: (i) 10 end-stage cirrhosis (ii) 10 cirrhosis associated with HCC samples at a distance of at least 3 cm; (iii) 5 low-grade dysplastic nodules; (iv) 5 high-grade dysplastic nodules; (v) 10 early HCCs and (vi) 20 progressed HCC |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | Human HCC |
Year of Publication | 2012 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |