CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2158
Detailed information
CancerLivER ID2158
Biomarker hnRNP K
Biomarker Name/Symbol (given in Publication)hnRNP K
BiomoleculeProtein
SubjectHuman
Degree of ValidityPotential tissue biomarker, either alone or in combination with serum AFP, for detection of early HCC; but not validated on independent datset
Experimental ConditionEarly HCC vs Late HCC
Cancer typeHepatocellular carcinoma
RegulationUpregulated in HCC
Level of significance p < 0.01
SourceSerum
PMID22760167
Type of BiomarkerDiagnostic
PathwayPlay a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences.
Cohort15 early HCC and 25 late HCC tissue samples
Sensitivity66.67%
Specificity84%
AccuracyNA
AUCNA
DiseaseHuman HCC
Year of Publication2012
Clinical trialNO
Clinical trial (NCT Number)NA

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