Detailed information |
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CancerLivER ID | 2158 |
Biomarker | hnRNP K |
Biomarker Name/Symbol (given in Publication) | hnRNP K |
Biomolecule | Protein |
Subject | Human |
Degree of Validity | Potential tissue biomarker, either alone or in combination with serum AFP, for detection of early HCC; but not validated on independent datset |
Experimental Condition | Early HCC vs Late HCC |
Cancer type | Hepatocellular carcinoma |
Regulation | Upregulated in HCC |
Level of significance | p < 0.01 |
Source | Serum |
PMID | 22760167 |
Type of Biomarker | Diagnostic |
Pathway | Play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. |
Cohort | 15 early HCC and 25 late HCC tissue samples |
Sensitivity | 66.67% |
Specificity | 84% |
Accuracy | NA |
AUC | NA |
Disease | Human HCC |
Year of Publication | 2012 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |