CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2109
Detailed information
CancerLivER ID2109
Biomarker DHCR24 Auto-antibody
Biomarker Name/Symbol (given in Publication)DHCR24 Auto-antibody
BiomoleculeProtein
SubjectHuman
Degree of ValidityA potential noninvasive biomarker for HCV-related liver disease and may facilitate the diagnosis of PIVKA-II and AFP-negative HCC and validated on independent dataset
Experimental ConditionNormal vs Chronic heaptitis (CHV)
Cancer typeChronic hepatitis C
RegulationUpregulated in CHC (Chronic Hepatitis C) v/s healthy
Level of significance p < 0.0001
SourceSerum
PMID26288822
Type of BiomarkerPrognostic
PathwayMultiple pathway (chronic inflammation, cirrhosis, cell death, and proliferation)
Cohort395 HCV-positive patients, including 133 chronic hepatitis (CHC), 85 liver cirrhosis (LCC), and 177 HCC (HCC-C) patients; 232 hepatitis B virus (HBV)-positive patients, including 103 chronic hepatitis (CHB), 56 liver cirrhosis (LCB), and 73 HCC (HCC-B) patients; and 24 healthy controls
Sensitivity70.06
Specificity100
AccuracyNA
AUC0.98
DiseaseHuman HCV,CHC, LCC HCC-B, HCC-C, CHB
Year of Publication2015
Clinical trialNO
Clinical trial (NCT Number)NA

         Raghava's group    CancerCSP    CancerSPP    CancerPDF    CancerTSP    CancerLSP    HCCPred   

Scroll to Top