| Detailed information |
|---|
| CancerLivER ID | 2055 |
| Biomarker | TRIM32 |
| Biomarker Name/Symbol (given in Publication) | TRIM32 |
| Biomolecule | Protein |
| Subject | Human |
| Degree of Validity | Potential prognostic marker and therapeutic target of HCC and validated on independent dataset |
| Experimental Condition | HCC v/s Normal; significant predictor for the overall survival time of HCC patients and positively correlated with histological grade, tumor sizes of patients |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Upregulated in HCC tumor tissues and HCC cell lines. |
| Level of significance | p < 0.05 |
| Source | Tissue |
| PMID | 27573002 |
| Type of Biomarker | Diagnostic and Prognostic |
| Pathway | Pro-apoptotic pathway, signaling pathways |
| Cohort | 116 paired primary HCC and adjacent non- tumorous tissues (90 males and 26 females, and contained 66 well-differentiated patients (Edmondson's grade I-II), 50 poorly differentiated patients (Edmondson's grade III-IV) and human hepatoma carcinoma cell lines include Huh7, HepG2, Hep3B, human hepatic L |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | Human HCC |
| Year of Publication | 2016 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |