Detailed information |
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CancerLivER ID | 2044 |
Biomarker | lncBRM |
Biomarker Name/Symbol (given in Publication) | lncBRM |
Biomolecule | LncRNA |
Subject | Human |
Degree of Validity | lncBRM and YAP1 signalling may serve as biomarkers for diagnosis and potential drug targets for HCC and validated on different patients cohorts |
Experimental Condition | Liver CSCs (Cancer stem cells) and early and advanced HCC tumours |
Cancer type | Hepatocellular carcinoma |
Regulation | Upregulated in HCC tumours and liver CSCs |
Level of significance | p < 0.001 |
Source | Tissue |
PMID | 27905400 |
Type of Biomarker | Diagnostic and Prognostic |
Pathway | It is required for self-renewal and maintenance of liver CSCs |
Cohort | HCC cell lines Huh7, Hep3B and various patients cohorts of PLC (GSE66529, GSE14520, GSE25097 and GSE54238) |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | Human HCC |
Year of Publication | 2016 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |