Detailed information |
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CancerLivER ID | 2029 |
Biomarker | ATF3-008 |
Biomarker Name/Symbol (given in Publication) | ATF3-008 |
Biomolecule | LncRNA |
Subject | Human |
Degree of Validity | Potential diagnostic and prognostic biomarker for ICC metastasis and validated on independent dataset |
Experimental Condition | ICC v/s Normal; significantly downregulated in ICC with tumor metastasis |
Cancer type | Cholangiocarcinoma |
Regulation | Downregulated in ICC (with log fold change of more than 2) |
Level of significance | p < 0.05 |
Source | Tissue |
PMID | 28401021 |
Type of Biomarker | Diagnostic and Prognostic |
Pathway | ERBB, JAK/STAT, MAPK, VEGF and WNT signaling pathways |
Cohort | 4 paired cancerous and adjacent non-cancerous tissues in training and 32 of ICC patients and 4 of normal subjects for validation |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | Intrahepatic cholangiocarcinoma |
Year of Publication | 2017 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |