| Detailed information |
|---|
| CancerLivER ID | 2022 |
| Biomarker | circZFR |
| Biomarker Name/Symbol (given in Publication) | circZFR |
| Biomolecule | circRNAs |
| Subject | Human |
| Degree of Validity | Novel biomarkers and therapeutic targets for HCC and validated on independent dataset |
| Experimental Condition | Liver cancer v/s Normal |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Upregulated in liver cancer (with fold change 13.22) |
| Level of significance | p < 0.001 |
| Source | Tissue |
| PMID | 28727484 |
| Type of Biomarker | Diagnostic |
| Pathway | p53 signaling pathway and pathways involved in angiogenesis and cell cycle. |
| Cohort | Training dataset contain 30 pairs tissues (cancer and adjacent normal) are recruited from China-Japan Union hospital of Jilin University and validation dataset contain 40 paired clinical samples of liver cancer tissues and their paired adjacent normal liver tissues |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | 0.71 |
| Disease | Human liver cancer |
| Year of Publication | 2017 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |