Detailed information |
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CancerLivER ID | 2016 |
Biomarker | G6PC |
Biomarker Name/Symbol (given in Publication) | G6PC |
Biomolecule | Protein |
Subject | Human Cell lines |
Degree of Validity | Biomarker to distinguish embryonal from fetal components of Hepatoblastoma; but not validated in human subjects |
Experimental Condition | Embryonal v/s fetal HB (Subtypes of Hepatoblastoma) |
Cancer type | Hepatoblastoma |
Regulation | Fetal HBs express G6PC preferentially than embryonal. |
Level of significance | p < 0.0001 |
Source | Tissue |
PMID | 28923827 |
Type of Biomarker | Potential Diagnostic * |
Pathway | increased Notch versus Wnt path- way activation |
Cohort | Four HCC (Huh-1,Hep3B, HLE, and HLF) and four HB (Hep-U2, Huh-6, HepG2, and Hep293TT) cell lines |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | Human Hb (Fetal) |
Year of Publication | 2017 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |